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NCT04673877 · ClinicalTrials.gov registry record · Phase 1

Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration

A Phase 1 study of Infection and Hand Injuries, sponsored by Mayo Clinic.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target
1
Study location

NCT04673877: Completed Phase 1 study of Infection and Hand Injuries, sponsored by Mayo Clinic.

NCT04673877 is a Phase 1 study of Infection and Hand Injuries that has completed, run by Mayo Clinic. The registered enrollment target is 20 participants, below the 726-participant average among 41 other Infection trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04673877, a Phase 1 study of Infection and Hand Injuries, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (upper extremity) is more effective at preventing infection than the current standard dose which is given intravenously (IV).

Primary Outcome

Tissue concentrations of vancomycin in the hand and wrist following Bier Block administration versus systemic IV administration

Interventions

  • DRUG Vancomycin
  • DRUG Systemic IV Vancomycin
  • PROCEDURE Bier Block

Study Locations (1)

Arizona

  • Mayo Clinic in Arizona - Phoenix

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2021-08-26
Est. Completion 2022-08-17
Phase Phase 1
Mayo Clinic

2,844 total trials

What the finished NCT04673877 record still lists

NCT04673877 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 726-participant average among 41 other Infection trials with a reported enrollment target (97% lower).

The record links to 5 conditions, with Infection appearing as the primary indexed condition, and to 3 interventions - of which Vancomycin is the first listed.

NCT04673877 reports a single indexed study location in Arizona.

Frequently Asked Questions

What is clinical trial NCT04673877 about?

NCT04673877 is a clinical study titled "Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration". The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (upper extremity) is more effective at preventing infection than the current standard dose which is given intravenously (IV).

What is the current status of trial NCT04673877?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2021-08-26. Estimated completion is 2022-08-17.

What conditions does trial NCT04673877 study?

This clinical trial studies the following conditions: Infection, Hand Injuries, Hand Arthritis, Hand Injury Wrist, Hand Injuries and Disorders.

What interventions are being tested in trial NCT04673877?

The interventions under investigation include: Vancomycin (DRUG), Systemic IV Vancomycin (DRUG), Bier Block (PROCEDURE).

Who is sponsoring clinical trial NCT04673877?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04673877 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Infection

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04673877's enrollment target sits among peer trials

20 38th of 41 higher than 4 of 41 other Infection trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04673877, the US trial registry maintained by the National Library of Medicine. NCT04673877 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.