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ClinicalTrials.gov 6 recruiting now full pipeline

Acne: full-pipeline trial registry

6 of 27 indexed Acne trials are currently recruiting.

Corpus placement: #598 of 28,707 conditions by registered trial count.

27 US clinical trials · 6 currently recruiting · #598 of 28,707 conditions by registered trial count

Acne: 27 US clinical trials tracked, 6 recruiting.

Acne is the subject of 27 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Galderma R&D, running 4 of these trials.

Enrollment posture brief

Registry condition acne

OPEN 6 | RECR 22% | LATE 9 | EARLY 6 | RANK #598 | SPON 4

Nearest open-share peer: Acute Otitis Media (22% recruiting · 9 trials)

Alopecia Areata55.6%Acute Ischemic Stroke44.4%Anatomic Stage IIIC Breast C33.3%Adenocarcinoma25.9%Acne (this)22%
Open-enrollment share among volume-matched conditions near Acne

Acne lists 6 open slots (22% of 27 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acne on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acne is recruiting below its size-band peers.

    6 of 27 indexed trials (22.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Acne trials is spread across many organizations.

    Galderma R&D accounts for 4 of 27 trials (14.8%). 22 distinct sponsors appear on at least one study for this condition label.

  3. Typical Acne enrolment sits around 72 participants.

    Median target enrolment is 72 among the 27 trials that report a genuine target (sentinel values excluded). 16 of those (59.3%) plan for fewer than 100 participants.

  4. Acne research is mostly interventional.

    25 interventional and 2 observational studies make up this index (92.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 21Phase 31Phase 48

Open and recent trials

27 total, page 1 of 1

RECRUITING Phase 1 260 participants

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Sanofi Pasteur, a Sanofi Company

NCT06316297

RECRUITING NA 200 participants

AVAVA MIRIA General Use

AVAVA

NCT06868615

RECRUITING NA 150 participants

The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis

Integrative Skin Science and Research

NCT05942248

RECRUITING Phase 1 128 participants

Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne

Sagimet Biosciences

NCT06989840

RECRUITING Phase 1 120 participants

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne

Sanofi Pasteur, a Sanofi Company

NCT07013747

RECRUITING NA 10 participants

Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production

Austin Institute for Clinical Research

NCT06376110

ACTIVE NOT RECRUITING NA 500 participants

Clinical Study to Evaluate the Safety and Efficacy of Candela Technology

Candela Corporation

NCT06202274

ACTIVE NOT RECRUITING Phase 4 350 participants

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne

University of Pennsylvania

NCT04582383

ACTIVE NOT RECRUITING Early Phase 1 72 participants

Experience With Topical Acne Treatment

Wake Forest University Health Sciences

NCT05582434

COMPLETED Phase 3 1,001 participants

Clinical End Point Study of Generic Adapalene and Benzoyl Peroxide Gel Versus Epiduo® Forte Gel in Treatment of Acne Vulgaris

Actavis

NCT02651220

COMPLETED Phase 4 128 participants

Comparison Study of Topical Acne Regimens

MedDerm Associates

NCT00913185

COMPLETED Phase 4 127 participants

A Clinical Trial to Evaluate the Efficacy of Two Acne Treatments

Galderma R&D

NCT02755545

COMPLETED NA 102 participants

RCT of an Oral Acne Supplement for Adult Women

Nutraceutical Wellness

NCT06097871

COMPLETED Phase 4 81 participants

Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris

Galderma R&D

NCT01951417

COMPLETED Phase 2 73 participants

Exploratory Study to Evaluate the Efficacy and Safety of CD07223 Gel in Subjects With Acne

Galderma R&D

NCT01106807

COMPLETED NA 63 participants

Joovvin' for Your Skin Health Study

ProofPilot

NCT04471896

COMPLETED Phase 4 61 participants

Analysis of Adherence & Associated Factors in Teenagers Undergoing Treatment of Acne Vulgaris With Differin® Gel 0.1%

Galderma R&D

NCT00437151

COMPLETED 59 participants

Sleep, Circadian Rhythm & Skin Health

University Hospitals Cleveland Medical Center

NCT02457000

COMPLETED NA 38 participants

An Exploratory Investigation of a Male Focused Skincare Supplement

Let's Dis

NCT05319847

COMPLETED NA 38 participants

An Exploratory Investigation of a Novel Skincare Regimen

Trophy Skin

NCT05517720

COMPLETED NA 30 participants

Study Evaluating the Efficacy and Safety of TheraClearX on Mitigating Mild to Moderate Acne

Ablon Skin Institute Research Center

NCT06043102

COMPLETED Phase 4 25 participants

Profiling the Skin Microbiome in Response to Altreno in Acne Patients

Beth Israel Deaconess Medical Center

NCT04548349

COMPLETED NA 22 participants

The Effects of Cetyl Tranexamate Mesylate on the Appearance of Acne-Related Hyperpigmentation

Integrative Skin Science and Research

NCT06080035

COMPLETED Phase 4 20 participants

Efficacy and Safety of Aczone 7.5% Gel in the Treatment of Truncal Acne Vulgaris

Derm Research, P

NCT02944461

COMPLETED Phase 1 20 participants

Absorption and Systematic Pharmacokinetics of Topically Applied IDP-120 Gel

Bausch Health Americas

NCT02850003

COMPLETED 15 participants

Comparison of Stacked-Pulses Vs. Double-Pass Treatments of Facial Acne With a 1450 Nm Laser

Skincare Physicians of Chestnut Hill

NCT00306371

COMPLETED Phase 4 12 participants

Administration of Oral Extended Release Minocycline for Assessment of Skin and Plasma Concentrations of Minocycline

BioPharmX

NCT02695446

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 1
Phase 3 1
Phase 4 8

Named interventions

Most-linked intervention names on Acne records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Acne mRNA vaccine Biological
2 trials
Placebo Other
2 trials
Joovv Mini Device
1 trials
Skin Nutraceutical Supplement Dietary supplement
1 trials
Foam Wash Other
1 trials
Moisturizer SPF 30 Other
1 trials
Adapalene/BPO Gel Drug
1 trials
Adapalene and Benzoyl Peroxide Gel Drug
1 trials

US sites by state

Facility locations filed on Acne trials. A trial with sites in several states counts in each.

California 11 trials
Texas 6 trials
Florida 6 trials
North Carolina 5 trials
Massachusetts 5 trials
Arizona 3 trials
Pennsylvania 2 trials
Ohio 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acne page

27 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acne condition card totals 27 registered trials; most-linked intervention Acne mRNA vaccine; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.