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Acne clinical trials
Every US clinical trial registered for Acne — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
27 US clinical trials · 6 currently recruiting
The research picture
Acne has 27 registered US clinical trials, 6 of them open to new participants right now — about 22% of the total.
- 6
- recruiting participants now
- 22%
- of trials open to enrollment
- 9
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Galderma R&D
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
NCT06316297
AVAVA MIRIA General Use
AVAVA
NCT06868615
The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis
Integrative Skin Science and Research
NCT05942248
Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne
Sagimet Biosciences
NCT06989840
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
Sanofi Pasteur, a Sanofi Company
NCT07013747
Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production
Austin Institute for Clinical Research
NCT06376110
Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
Candela Corporation
NCT06202274
Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne
University of Pennsylvania
NCT04582383
Experience With Topical Acne Treatment
Wake Forest University Health Sciences
NCT05582434
Clinical End Point Study of Generic Adapalene and Benzoyl Peroxide Gel Versus Epiduo® Forte Gel in Treatment of Acne Vulgaris
Actavis
NCT02651220
Comparison Study of Topical Acne Regimens
MedDerm Associates
NCT00913185
A Clinical Trial to Evaluate the Efficacy of Two Acne Treatments
Galderma R&D
NCT02755545
RCT of an Oral Acne Supplement for Adult Women
Nutraceutical Wellness
NCT06097871
Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris
Galderma R&D
NCT01951417
Exploratory Study to Evaluate the Efficacy and Safety of CD07223 Gel in Subjects With Acne
Galderma R&D
NCT01106807
Joovvin' for Your Skin Health Study
ProofPilot
NCT04471896
Analysis of Adherence & Associated Factors in Teenagers Undergoing Treatment of Acne Vulgaris With Differin® Gel 0.1%
Galderma R&D
NCT00437151
Sleep, Circadian Rhythm & Skin Health
University Hospitals Cleveland Medical Center
NCT02457000
An Exploratory Investigation of a Male Focused Skincare Supplement
Let's Dis
NCT05319847
An Exploratory Investigation of a Novel Skincare Regimen
Trophy Skin
NCT05517720
Study Evaluating the Efficacy and Safety of TheraClearX on Mitigating Mild to Moderate Acne
Ablon Skin Institute Research Center
NCT06043102
Profiling the Skin Microbiome in Response to Altreno in Acne Patients
Beth Israel Deaconess Medical Center
NCT04548349
The Effects of Cetyl Tranexamate Mesylate on the Appearance of Acne-Related Hyperpigmentation
Integrative Skin Science and Research
NCT06080035
Efficacy and Safety of Aczone 7.5% Gel in the Treatment of Truncal Acne Vulgaris
Derm Research, P
NCT02944461
Absorption and Systematic Pharmacokinetics of Topically Applied IDP-120 Gel
Bausch Health Americas
NCT02850003
Comparison of Stacked-Pulses Vs. Double-Pass Treatments of Facial Acne With a 1450 Nm Laser
Skincare Physicians of Chestnut Hill
NCT00306371
Administration of Oral Extended Release Minocycline for Assessment of Skin and Plasma Concentrations of Minocycline
BioPharmX
NCT02695446
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Acne Trial Landscape
ClinicalTrials.gov lists 27 US studies indexed under Acne, and 6 of those are currently open to recruitment — roughly 22% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Acne shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Acne is led by Galderma R&D with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Acne?
PlainTrial tracks 27 US clinical trials for Acne, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Acne?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.