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NCT07110636 · ClinicalTrials.gov registry record · NA
Microbial Cell-free Metagenomic Sequencing for Suspected Infections in Adult Immunocompromised Outpatients
A NA study of Infection and Parasitic Disease, sponsored by Karius.
- Recruiting
- Registry status
- NA
- Development phase
- 2,000
- Enrollment target
- 6
- Study locations
NCT07110636: Recruiting NA study of Infection and Parasitic Disease, sponsored by Karius.
NCT07110636 is a NA study of Infection and Parasitic Disease that is actively recruiting participants, run by Karius. The registered enrollment target is 2,000 participants, above the 678-participant average among 41 other Infection trials with a reported enrollment target (195% higher). The trial reports 6 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07110636, a NA study of Infection and Parasitic Disease, is actively recruiting participants, sponsored by Karius.
- RECRUITING
- Registry status
- NA
- Development phase
- 2,000 participants
- Enrollment target
- 6
- Study locations
Study Summary
This clinical trial is designed to evaluate if adding the Karius Spectrum™ plasma test to usual care diagnostic tests, compared to usual care testing alone, among immunocompromised participants presenting with suspected infection in the outpatient setting leads to faster infection diagnosis and treatment. Participants will give a blood sample one time to be used for the testing. Information about the participant's illness and any treatments within 30 days following enrollment will be recorded.
Primary Outcome
For each cohort, to evaluate whether the addition of Karius Spectrum testing to usual care testing reduces the time to identification of a pathogen-specific etiology, compared to usual care testing alone, in participants with suspected infection in the outpatient setting.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Metagenomic plasma-based test for agnostic pathogen detection
Study Locations (6)
Massachusetts
- Brigham and Women's Hospital - Boston
- Beth Israel Deaconess Medical Center - Boston
California
- University of California San Francisco - San Francisco
Louisiana
- Ochsner Medical Center - New Orleans
Nebraska
- University of Nebraska Medical Center - Omaha
New York
- Montefiore Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 2025-10-27 |
| Est. Completion | 2028-12-31 |
| Phase | NA |
What NCT07110636 shows while recruiting
NCT07110636 is an interventional study that assigns participants to a tested intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus, above the 678-participant average among 41 other Infection trials with a reported enrollment target (195% higher).
The record links to 5 conditions, with Infection appearing as the primary indexed condition, and to 1 intervention - of which Metagenomic plasma-based test for agnostic pathogen detection is the first listed.
NCT07110636 lists 6 locations in 5 states (Massachusetts, California, Louisiana).
Frequently Asked Questions
What is clinical trial NCT07110636 about?
NCT07110636 is a clinical study titled "Microbial Cell-free Metagenomic Sequencing for Suspected Infections in Adult Immunocompromised Outpatients". This clinical trial is designed to evaluate if adding the Karius Spectrum™ plasma test to usual care diagnostic tests, compared to usual care testing alone, among immunocompromised participants presenting with suspected infection in the outpatient setting leads to faster infection diagnosis and trea...
What is the current status of trial NCT07110636?
This trial is currently recruiting. It is a NA study. The enrollment target is 2,000 participants. The study started on 2025-10-27. Estimated completion is 2028-12-31.
What conditions does trial NCT07110636 study?
This clinical trial studies the following conditions: Infection, Parasitic Disease, Infections, Bacterial, Infections, Fungal, Infection Viral.
What interventions are being tested in trial NCT07110636?
The interventions under investigation include: Metagenomic plasma-based test for agnostic pathogen detection (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07110636?
This trial is sponsored by Karius, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07110636 being conducted?
This trial has 6 study locations across California, Louisiana, Massachusetts, Nebraska, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Infection
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07110636's enrollment target sits among peer trials
2,000 5th of 41 higher than 37 of 41 other Infection trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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