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NCT02351258 · ClinicalTrials.gov registry record · NA
Community Central Line Infection Prevention Trial
A NA study of Infection, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
- 16
- Study locations
NCT02351258: Completed NA study of Infection, sponsored by Johns Hopkins University.
NCT02351258 is a NA study of Infection that has completed, run by Johns Hopkins University. The registered enrollment target is 16 participants, below the 726-participant average among 41 other Infection trials with a reported enrollment target (98% lower). The trial reports 16 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02351258, a NA study of Infection, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
- 16
- Study locations
Study Summary
The overall goal of this Community Central Line Infection Prevention (CCLIP) trial, supported by grant R01 HS022870 from the Agency for Healthcare Research and Quality, is to determine whether use of a promising new intervention, namely 70% isopropyl alcohol embedded protective caps on central lines, in the home setting is associated with a reduction in ambulatory central line-associated bloodstream infections (CLABSI) in a high-risk population of pediatric hematology/oncology patients. Despite successes in CLABSI reduction efforts for inpatients, it remains unknown what generalizable best practices should be with chronic central lines in the home setting and how effective involving patients and caregivers across multiple institutions in CLABSI reduction efforts will be. This research will involve a cluster-randomized, cross-over design, clinical trial. This proposal will focus on the caregivers integral to ambulatory pediatric central line care: patients and families. The specific aims of the proposed research program are: Specific Aim #1: Evaluate whether use of 70% isopropyl alcohol embedded protective caps on central lines reduces the rate of CLABSI in ambulatory pediatric hematology/oncology patients. Hypothesis: Use of 70% isopropyl alcohol embedded protective caps on central lines will be associated with at least a 25% reduction in the ambulatory CLABSI rate for pediatric hematology/oncology patients. Specific Aim #2: Evaluate whether use of 70% isopropyl alcohol embedded protective caps on central lines reduces the rate of all positive blood cultures in ambulatory pediatric hematology/oncology patients. Hypothesis: Use of 70% isopropyl alcohol embedded protective caps on central lines will be associated with at least a 25% reduction in the positive blood culture rate at home for pediatric hematology/oncology patients. Specific Aim #3: Evaluate whether the use of 70% isopropyl alcohol embedded protective caps on central lines changes the distribution of
Primary Outcome
To obtain rate of ambulatory central line associated blood stream infections in ambulatory patients
Conditions Studied
Interventions
- OTHER Usual Care
- DEVICE 70% Isopropyl alcohol embedded caps
Study Locations (16)
Maryland
- Johns Hopkins Children's Center - Baltimore
- Johns Hopkins University - Baltimore
Ohio
- Akron Children's Hospital - Akron
- Nationwide Children's Hospital - Columbus
Alabama
- Children's Hospital of Alabama - Birmingham
Arkansas
- Arkansas Children's Hospital - Little Rock
Colorado
- Children's Hospital of Colorado - Aurora
Delaware
- Nemours Alfred Dupont Hospital for Children - Wilmington
Florida
- University of Florida Children's Hospital - Gainesville
Kentucky
- Norton Children's Hospital - Louisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2015-11 |
| Est. Completion | 2019-09-09 |
| Phase | NA |
What the finished NCT02351258 record still lists
NCT02351258 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 726-participant average among 41 other Infection trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Infection appearing as the primary indexed condition, and to 2 interventions - of which Usual Care is the first listed.
NCT02351258 lists 16 locations in 14 states (Maryland, Ohio, Alabama).
Frequently Asked Questions
What is clinical trial NCT02351258 about?
NCT02351258 is a clinical study titled "Community Central Line Infection Prevention Trial". The overall goal of this Community Central Line Infection Prevention (CCLIP) trial, supported by grant R01 HS022870 from the Agency for Healthcare Research and Quality, is to determine whether use of a promising new intervention, namely 70% isopropyl alcohol embedded protective caps on central lines...
What is the current status of trial NCT02351258?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2015-11. Estimated completion is 2019-09-09.
What conditions does trial NCT02351258 study?
This clinical trial studies the following conditions: Infection.
What interventions are being tested in trial NCT02351258?
The interventions under investigation include: Usual Care (OTHER), 70% Isopropyl alcohol embedded caps (DEVICE).
Who is sponsoring clinical trial NCT02351258?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02351258 being conducted?
This trial has 16 study locations across Alabama, Arkansas, Colorado, Delaware, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02351258's enrollment target sits among peer trials
16 39th of 41 higher than 3 of 41 other Infection trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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