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NCT02299921 · ClinicalTrials.gov registry record
Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure
A clinical trial of Alcohol Abuse and Infection, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT02299921: Recruiting study of Alcohol Abuse and Infection, sponsored by University of Colorado, Denver.
NCT02299921 is a study of Alcohol Abuse and Infection that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 300 participants, below the 707-participant average among 46 other Alcohol Abuse trials with a reported enrollment target (58% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02299921, a study of Alcohol Abuse and Infection, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
This study plans to learn more about people who are sick in the hospital with a lung infection, or respiratory failure. Respiratory failure, or severe lung failure, is a life-threatening disease. When it happens, the lungs have trouble carrying out their normal function of getting oxygen into the blood, and removing carbon dioxide from the body. Investigators are conducting this study to see what drinking too much alcohol, using tobacco products, or using drugs (both legal and illegal) may do to lung infections and respiratory failure. Subjects are asked to be in this research study because they are thought to have a lung infection and may also have respiratory failure. Alcohol, tobacco, and drug use have been linked to lung infections, respiratory failure, and even death, but the reasons for this aren't known. People who use unhealthy amounts of alcohol, tobacco, and or drugs may be more at risk for lung infections, and for severe complications due to lung infection. Subject participation is important whether or not you use alcohol and or drugs.
Primary Outcome
Among medical ICU (MICU) patients who remain in ICU greater than or equal to 48 hours: Prevalence of alcohol use disorders (AUDs), drug use disorders (DUDs), their combination (both), or no AUD/DUDs. Absolute value, and change over 7 days, in serum/urine/exhaled breath condensate/hair cortisol, corticotropin releasing hormone (CRH), adenovirus proteinase (AVP), and adrenocorticotropic hormone (ACTH), stratified by AUD/DUD/both/neither. 3 Month and 6 Month follow up were added to this outcome mea
Conditions Studied
Interventions
- OTHER Characterize alcohol and drug use
Study Locations (1)
Colorado
- University of Colorado Hospital - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2014-11 |
| Est. Completion | 2029-04-30 |
What NCT02299921 shows while recruiting
NCT02299921 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 707-participant average among 46 other Alcohol Abuse trials with a reported enrollment target (58% lower).
The record links to 4 conditions, with Alcohol Abuse appearing as the primary indexed condition, and to 1 intervention - of which Characterize alcohol and drug use is the first listed.
NCT02299921 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT02299921 about?
NCT02299921 is a clinical study titled "Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure". This study plans to learn more about people who are sick in the hospital with a lung infection, or respiratory failure. Respiratory failure, or severe lung failure, is a life-threatening disease. When it happens, the lungs have trouble carrying out their normal function of getting oxygen into the bl...
What is the current status of trial NCT02299921?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2014-11. Estimated completion is 2029-04-30.
What conditions does trial NCT02299921 study?
This clinical trial studies the following conditions: Alcohol Abuse, Infection, Lung Injury, Drugs of Abuse.
What interventions are being tested in trial NCT02299921?
The interventions under investigation include: Characterize alcohol and drug use (OTHER).
Who is sponsoring clinical trial NCT02299921?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02299921 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Abuse
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02299921's enrollment target sits among peer trials
300 17th of 46 higher than 30 of 46 other Alcohol Abuse trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Abuse trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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