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NCT05828680 · ClinicalTrials.gov registry record
Circadian Rhythm Disruption in the Hospital Intensive Care Environment
A clinical trial of Cardiovascular Diseases and Surgery, sponsored by University of Pennsylvania.
- Active
- Registry status
- 15
- Enrollment target
- 1
- Study location
NCT05828680: Active study of Cardiovascular Diseases and Surgery, sponsored by University of Pennsylvania.
NCT05828680 is a study of Cardiovascular Diseases and Surgery that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 15 participants, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05828680, a study of Cardiovascular Diseases and Surgery, is active but no longer recruiting, sponsored by University of Pennsylvania.
- ACTIVE NOT RECRUITING
- Registry status
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
Abrupt changes to one's lifestyle disrupt biorhythms. Acute effects are well known from jet lag where transmeridian travel leads to insomnia, fatigue, irritability, gastrointestinal symptoms and other complaints. Several studies in the hospital environment reported dampened and misaligned biorhythms, suggesting that the inpatient experience is replete with circadian disruptors. However, comprehensive assessments of how circadian clocks are affected in intensive care and how this predicts post-operative recovery and risk are largely missing.
Primary Outcome
Variance in sleep depth assessed as percent REM sleep of total sleep time (TST)
Conditions Studied
Interventions
- OTHER Observation
Study Locations (1)
Pennsylvania
- Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2023-03-15 |
| Est. Completion | 2028-12 |
What the registry record for NCT05828680 still lists
NCT05828680 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 1 intervention - of which Observation is the first listed.
NCT05828680 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05828680 about?
NCT05828680 is a clinical study titled "Circadian Rhythm Disruption in the Hospital Intensive Care Environment". Abrupt changes to one's lifestyle disrupt biorhythms. Acute effects are well known from jet lag where transmeridian travel leads to insomnia, fatigue, irritability, gastrointestinal symptoms and other complaints. Several studies in the hospital environment reported dampened and misaligned biorhythms...
What is the current status of trial NCT05828680?
This trial is currently active not recruiting. The enrollment target is 15 participants. The study started on 2023-03-15. Estimated completion is 2028-12.
What conditions does trial NCT05828680 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Surgery.
What interventions are being tested in trial NCT05828680?
The interventions under investigation include: Observation (OTHER).
Who is sponsoring clinical trial NCT05828680?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05828680 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05828680's enrollment target sits among peer trials
15 289th of 300 higher than 10 of 300 other Cardiovascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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