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NCT06043310 · ClinicalTrials.gov registry record
Estrogen and Microvascular Function
A clinical trial of Cardiovascular Diseases and Estrogen, sponsored by Medical College of Wisconsin.
- Active
- Registry status
- 45
- Enrollment target
- 1
- Study location
NCT06043310: Active study of Cardiovascular Diseases and Estrogen, sponsored by Medical College of Wisconsin.
NCT06043310 is a study of Cardiovascular Diseases and Estrogen that is active but no longer recruiting, run by Medical College of Wisconsin. The registered enrollment target is 45 participants, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06043310, a study of Cardiovascular Diseases and Estrogen, is active but no longer recruiting, sponsored by Medical College of Wisconsin.
- ACTIVE NOT RECRUITING
- Registry status
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to learn how long-term use of estrogen affects blood vessels in healthy adults. Participants will: * give one blood draw of 5 mL * have one Dexa Scan taken to measure adipose and muscle mass * have a camera placed under the tongue to take pictures of blood vessels * have 2 laser Doppler microdialysis catheters placed on the forearm to monitor blood vessels before and after local drug infusion Researchers will compare blood vessel function of those who take estrogen to those who do not.
Primary Outcome
Cutaneous vascular conductance in response to acetylcholine, L-NAME, and sodium nitroprusside infusions will be calculated as percentage of cardiovascular conductance.
Conditions Studied
Interventions
- DRUG Acetylcholine
- DRUG Sodium Nitroprusside
- DRUG Nω-nitro-L-arginine methyl ester (L-NAME)
Study Locations (1)
Wisconsin
- Froedtert Hospital - Wauwatosa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2023-10-12 |
| Est. Completion | 2031-12 |
What the registry record for NCT06043310 still lists
NCT06043310 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower).
The record links to 4 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 3 interventions - of which Acetylcholine is the first listed.
NCT06043310 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT06043310 about?
NCT06043310 is a clinical study titled "Estrogen and Microvascular Function". The goal of this study is to learn how long-term use of estrogen affects blood vessels in healthy adults. Participants will: * give one blood draw of 5 mL * have one Dexa Scan taken to measure adipose and muscle mass * have a camera placed under the tongue to take pictures of blood vessels * have ...
What is the current status of trial NCT06043310?
This trial is currently active not recruiting. The enrollment target is 45 participants. The study started on 2023-10-12. Estimated completion is 2031-12.
What conditions does trial NCT06043310 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Estrogen, Microvasculature, Oral Contraceptive Use.
What interventions are being tested in trial NCT06043310?
The interventions under investigation include: Acetylcholine (DRUG), Sodium Nitroprusside (DRUG), Nω-nitro-L-arginine methyl ester (L-NAME) (DRUG).
Who is sponsoring clinical trial NCT06043310?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06043310 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06043310's enrollment target sits among peer trials
45 243rd of 300 higher than 55 of 300 other Cardiovascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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