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Estrogen and Microvascular Function
NCT06043310 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this study is to learn how long-term use of estrogen affects blood vessels in healthy adults. Participants will: * give one blood draw of 5 mL * have one Dexa Scan taken to measure adipose and muscle mass * have a camera placed under the tongue to take pictures of blood vessels * have 2 laser Doppler microdialysis catheters placed on the forearm to monitor blood vessels before and after local drug infusion Researchers will compare blood vessel function of those who take estrogen to those who do not.
Conditions Studied
Interventions
- DRUG Acetylcholine
- DRUG Sodium Nitroprusside
- DRUG Nω-nitro-L-arginine methyl ester (L-NAME)
Study Locations (1)
Wisconsin
- Froedtert Hospital — Wauwatosa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2023-10-12 |
| Est. Completion | 2031-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06043310
The ClinicalTrials.gov registry entry for NCT06043310 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical College of Wisconsin, which has 614 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 3 interventions — of which Acetylcholine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06043310 reports 1 study location spanning 1 distinct geographic area — top geographies include Wisconsin. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06043310 about?
NCT06043310 is a clinical study titled "Estrogen and Microvascular Function". The goal of this study is to learn how long-term use of estrogen affects blood vessels in healthy adults. Participants will: * give one blood draw of 5 mL * have one Dexa Scan taken to measure adipose and muscle mass * have a camera placed under the tongue to take pictures of blood vessels * have ...
What is the current status of trial NCT06043310?
This trial is currently active not recruiting. The enrollment target is 45 participants. The study started on 2023-10-12. Estimated completion is 2031-12.
What conditions does trial NCT06043310 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Estrogen, Microvasculature, Oral Contraceptive Use. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06043310?
The interventions under investigation include: Acetylcholine (DRUG), Sodium Nitroprusside (DRUG), Nω-nitro-L-arginine methyl ester (L-NAME) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06043310?
This trial is sponsored by Medical College of Wisconsin, which has 614 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06043310 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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