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NCT07442578 · ClinicalTrials.gov registry record · NA
Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial
A NA study of Cardiovascular Diseases and Cardiotoxicity, sponsored by Dana-Farber Cancer Institute.
- Active
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07442578: Active NA study of Cardiovascular Diseases and Cardiotoxicity, sponsored by Dana-Farber Cancer Institute.
NCT07442578 is a NA study of Cardiovascular Diseases and Cardiotoxicity that is active but no longer recruiting, run by Dana-Farber Cancer Institute. The registered enrollment target is 20 participants, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07442578, a NA study of Cardiovascular Diseases and Cardiotoxicity, is active but no longer recruiting, sponsored by Dana-Farber Cancer Institute.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This trial aims to evaluate the impact of exercise intensity on cardiac health in young adult survivors of childhood cancer previously treated with anthracyclines.
Primary Outcome
Average E/e' ratio assessed by echocardiography using Doppler methods per ASE/EACVI guidance. E is the early diastolic transmitral inflow velocity (pulsed-wave Doppler) and e' is early diastolic mitral annular tissue velocity (tissue Doppler); average e' is typically the mean of septal and lateral e'. Reported as change from baseline to post-intervention.
Conditions Studied
Interventions
- BEHAVIORAL HIIT Exercise Program
- BEHAVIORAL MICT Exercise Program
Study Locations (1)
Massachusetts
- Dana-Farber Cancer Institute - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-03-04 |
| Est. Completion | 2028-03-04 |
| Phase | NA |
What the registry record for NCT07442578 still lists
NCT07442578 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower).
The record links to 4 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 2 interventions - of which HIIT Exercise Program is the first listed.
NCT07442578 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07442578 about?
NCT07442578 is a clinical study titled "Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial". This trial aims to evaluate the impact of exercise intensity on cardiac health in young adult survivors of childhood cancer previously treated with anthracyclines.
What is the current status of trial NCT07442578?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-03-04. Estimated completion is 2028-03-04.
What conditions does trial NCT07442578 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Cardiotoxicity, Childhood Cancer Survivors, Anthracycline-induced Cardiotoxicity.
What interventions are being tested in trial NCT07442578?
The interventions under investigation include: HIIT Exercise Program (BEHAVIORAL), MICT Exercise Program (BEHAVIORAL).
Who is sponsoring clinical trial NCT07442578?
This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07442578 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07442578's enrollment target sits among peer trials
20 282nd of 300 higher than 14 of 300 other Cardiovascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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