Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05725499 · ClinicalTrials.gov registry record · NA
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
A NA study of Cardiovascular Diseases and Spinal Cord Injuries, sponsored by Kessler Foundation.
- Recruiting
- Registry status
- NA
- Development phase
- 5
- Enrollment target
- 1
- Study location
NCT05725499: Recruiting NA study of Cardiovascular Diseases and Spinal Cord Injuries, sponsored by Kessler Foundation.
NCT05725499 is a NA study of Cardiovascular Diseases and Spinal Cord Injuries that is actively recruiting participants, run by Kessler Foundation. The registered enrollment target is 5 participants, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05725499, a NA study of Cardiovascular Diseases and Spinal Cord Injuries, is actively recruiting participants, sponsored by Kessler Foundation.
- RECRUITING
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
- 1
- Study location
Study Summary
This project will investigate the effect of spinal cord transcutaneous stimulation on blood pressure in individuals with a chronic spinal cord injury who experience blood pressure instability, specifically, orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back to an upright position). The main questions it aims to answer are: 1. What are the various spinal sites and stimulation parameters that normalize and stabilize blood pressure during an orthostatic provocation (70 degrees tilt)? 2. Does training, i.e., exposure to repeated stimulation sessions, have an effect on blood pressure stability? Participants will undergo orthostatic tests (lying on a table that starts out flat, then tilts upward up to 70 degrees), with and without stimulation, and changes in their blood pressure will be evaluated.
Primary Outcome
Identify scTS spinal segments that restore systolic BP within the normotensive range (110-120 mmHg).
Conditions Studied
Interventions
- DEVICE Biostim-5 transcutaneous spinal stimulator
- DIAGNOSTIC_TEST Tilt-table orthostatic stress testing
Study Locations (1)
New Jersey
- Kessler Foundation - West Orange
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2023-02-01 |
| Est. Completion | 2026-08-01 |
| Phase | NA |
What NCT05725499 shows while recruiting
NCT05725499 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower).
The record links to 9 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 2 interventions - of which Biostim-5 transcutaneous spinal stimulator is the first listed.
NCT05725499 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT05725499 about?
NCT05725499 is a clinical study titled "The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)". This project will investigate the effect of spinal cord transcutaneous stimulation on blood pressure in individuals with a chronic spinal cord injury who experience blood pressure instability, specifically, orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back to...
What is the current status of trial NCT05725499?
This trial is currently recruiting. It is a NA study. The enrollment target is 5 participants. The study started on 2023-02-01. Estimated completion is 2026-08-01.
What conditions does trial NCT05725499 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Spinal Cord Injuries, Blood Pressure, Nervous System Diseases, Orthostatic Hypotension.
What interventions are being tested in trial NCT05725499?
The interventions under investigation include: Biostim-5 transcutaneous spinal stimulator (DEVICE), Tilt-table orthostatic stress testing (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05725499?
This trial is sponsored by Kessler Foundation, which has 104 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05725499 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05725499's enrollment target sits among peer trials
5 298th of 300 higher than 1 of 300 other Cardiovascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health
RECRUITING · NA
-
Identifying Strategies to Reduce Cardiovascular Risk Among Mothers of Young Children
RECRUITING · NA
-
Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
RECRUITING · NA
-
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
RECRUITING · NA
-
Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
RECRUITING · NA
-
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI