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NCT05656183 · ClinicalTrials.gov registry record · NA

CardioSeq: Impact of WGS in Individuals With CVD

A NA study of Cardiovascular Diseases, sponsored by Illumina.

Active
Registry status
NA
Development phase
1,500
Enrollment target
1
Study location

NCT05656183: Active NA study of Cardiovascular Diseases, sponsored by Illumina.

NCT05656183 is a NA study of Cardiovascular Diseases that is active but no longer recruiting, run by Illumina. The registered enrollment target is 1,500 participants, below the 26,969-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05656183, a NA study of Cardiovascular Diseases, is active but no longer recruiting, sponsored by Illumina.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
1,500 participants
Enrollment target
1
Study location

Study Summary

This is a prospective, single-center, open-label study to investigate the diagnostic efficacy of the TruGenome CVD test and its impact on clinical management compared to usual care in individuals with cardiovascular disease. Diagnostic yield and changes of management (CoM) will be assessed both within the WGS group and compared to a contemporaneous, matched (2:1) usual care (UC) group sourced from EHR records.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST TruGenome Cardiovascular Disease test

Study Locations (1)

Michigan

  • Henry Ford Health System - Detroit

Trial Details

FieldValue
Enrollment Target 1,500 participants
Start Date 2023-01-06
Est. Completion 2025-06
Phase NA
Illumina

11 total trials

What the registry record for NCT05656183 still lists

NCT05656183 is an interventional study that assigns participants to a tested intervention. Its 1,500 participants enrollment target places it among the larger protocols in the corpus, below the 26,969-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (94% lower).

The record links to 1 condition, with Cardiovascular Diseases appearing as the primary indexed condition, and to 1 intervention - of which TruGenome Cardiovascular Disease test is the first listed.

NCT05656183 reports a single indexed study location in Michigan.

Frequently Asked Questions

What is clinical trial NCT05656183 about?

NCT05656183 is a clinical study titled "CardioSeq: Impact of WGS in Individuals With CVD". This is a prospective, single-center, open-label study to investigate the diagnostic efficacy of the TruGenome CVD test and its impact on clinical management compared to usual care in individuals with cardiovascular disease. Diagnostic yield and changes of management (CoM) will be assessed both with...

What is the current status of trial NCT05656183?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 1,500 participants. The study started on 2023-01-06. Estimated completion is 2025-06.

What conditions does trial NCT05656183 study?

This clinical trial studies the following conditions: Cardiovascular Diseases.

What interventions are being tested in trial NCT05656183?

The interventions under investigation include: TruGenome Cardiovascular Disease test (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT05656183?

This trial is sponsored by Illumina, which has 11 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05656183 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiovascular Diseases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05656183's enrollment target sits among peer trials

1,500 44th of 300 higher than 257 of 300 other Cardiovascular Diseases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05656183, the US trial registry maintained by the National Library of Medicine. NCT05656183 (large enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.