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NCT00005398 · ClinicalTrials.gov registry record

University of North Carolina Alumni Heart Study

A clinical trial of Depression and Cardiovascular Diseases, sponsored by Duke University.

Active
Registry status
6,340
Enrollment target
1
Study location

NCT00005398: Active study of Depression and Cardiovascular Diseases, sponsored by Duke University.

NCT00005398 is a study of Depression and Cardiovascular Diseases that is active but no longer recruiting, run by Duke University. The registered enrollment target is 6,340 participants, above the 777-participant average among 679 other Depression trials with a reported enrollment target (716% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00005398, a study of Depression and Cardiovascular Diseases, is active but no longer recruiting, sponsored by Duke University.

ACTIVE NOT RECRUITING
Registry status
6,340 participants
Enrollment target
1
Study location

Study Summary

To continue surveillance of the participants in the University of North Carolina Alumni Heart Study, which tests the hypothesis that hostility and related psychosocial factors are involved in the pathogenesis of coronary heart disease.

Primary Outcome

This is a descriptive cohort study

Interventions

  • OTHER There is no intervention

Study Locations (1)

North Carolina

  • Duke University, Behavioral Medicine Research Center - Durham

Trial Details

FieldValue
Enrollment Target 6,340 participants
Start Date 1996-05
Est. Completion 2026-05
Duke University

1,725 total trials

What the registry record for NCT00005398 still lists

NCT00005398 is an observational study that tracks outcomes without assigning an intervention. Its 6,340 participants enrollment target places it among the larger protocols in the corpus, above the 777-participant average among 679 other Depression trials with a reported enrollment target (716% higher).

The record links to 4 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which There is no intervention is the first listed.

NCT00005398 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT00005398 about?

NCT00005398 is a clinical study titled "University of North Carolina Alumni Heart Study". To continue surveillance of the participants in the University of North Carolina Alumni Heart Study, which tests the hypothesis that hostility and related psychosocial factors are involved in the pathogenesis of coronary heart disease.

What is the current status of trial NCT00005398?

This trial is currently active not recruiting. The enrollment target is 6,340 participants. The study started on 1996-05. Estimated completion is 2026-05.

What conditions does trial NCT00005398 study?

This clinical trial studies the following conditions: Depression, Cardiovascular Diseases, Heart Diseases, Coronary Disease.

What interventions are being tested in trial NCT00005398?

The interventions under investigation include: There is no intervention (OTHER).

Who is sponsoring clinical trial NCT00005398?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00005398 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Depression

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00005398's enrollment target sits among peer trials

6,340 11th of 679 higher than 669 of 679 other Depression trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00005398, the US trial registry maintained by the National Library of Medicine. NCT00005398 (large enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.