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NCT02604563 · ClinicalTrials.gov registry record
Aging, Geriatric Syndromes and Clonal Hematopoiesis
A clinical trial of Cardiovascular Diseases and Aged, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- 2,000
- Enrollment target
- 1
- Study location
NCT02604563: Recruiting study of Cardiovascular Diseases and Aged, sponsored by Washington University School of Medicine.
NCT02604563 is a study of Cardiovascular Diseases and Aged that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 2,000 participants, below the 26,968-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02604563, a study of Cardiovascular Diseases and Aged, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- 2,000 participants
- Enrollment target
- 1
- Study location
Study Summary
In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, which entails a comprehensive multi-dimensional assessment of the health of an older adult, including measures of comorbidity, polypharmacy, functional status, cognition, depression, falls, social activities and social support. Given that aging is heterogeneous, geriatric assessment allows greater specificity for aging than chronological age alone.
Primary Outcome
-The investigators will sequence the coding region of some or all of the genes in an individual's blood cells and compare results to their matched mouth cells to define hematopoietic-specific mutations. The number of hematopoietic-specific mutations per individual and the frequency of individuals with mutations will be measured.
Conditions Studied
Interventions
- OTHER Cognitive Assessment
- OTHER Activities of Daily Living Questionnaire
- OTHER Instrumental Activities of Daily Living, subscale of the OARS
- OTHER Karnofsky Self-reported Performance Rating Scale
- OTHER Number of Falls
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 2016-03-10 |
| Est. Completion | 2030-04-30 |
What NCT02604563 shows while recruiting
NCT02604563 is an observational study that tracks outcomes without assigning an intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus, below the 26,968-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (93% lower).
The record links to 4 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 5 interventions - of which Cognitive Assessment is the first listed.
NCT02604563 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT02604563 about?
NCT02604563 is a clinical study titled "Aging, Geriatric Syndromes and Clonal Hematopoiesis". In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, whic...
What is the current status of trial NCT02604563?
This trial is currently recruiting. The enrollment target is 2,000 participants. The study started on 2016-03-10. Estimated completion is 2030-04-30.
What conditions does trial NCT02604563 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Aged, Geriatrics, Geriatric Syndromes.
What interventions are being tested in trial NCT02604563?
The interventions under investigation include: Cognitive Assessment (OTHER), Activities of Daily Living Questionnaire (OTHER), Instrumental Activities of Daily Living, subscale of the OARS (OTHER), Karnofsky Self-reported Performance Rating Scale (OTHER), Number of Falls (OTHER).
Who is sponsoring clinical trial NCT02604563?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02604563 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02604563's enrollment target sits among peer trials
2,000 38th of 300 higher than 260 of 300 other Cardiovascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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