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The Oxford Risk Factors And Non-Invasive Imaging Study
NCT05169333 · View on ClinicalTrials.gov ↗
Study Summary
ORFAN is a prospective, multi-centre, multi-ethnic cohort observational study collecting CT scans, biological material and outcomes data, to develop and validate novel biomarkers of cardiometabolic and other disease risk.
Conditions Studied
Study Locations (20)
Other
- Flinders University — Adelaide
- The University of Sydney — Sydney
- University Hospitals Leuven — Leuven
- Fudan University — Shanghai
- TEDA International Cardiovascular Hospital — Tianjin
- Almaviva Sante - Clinique Axium — Aix-en-Provence
- Friedrich-Alexander-Universitat Erlangen-Nurmberg — Erlangen
- University Hospital Ulm — Ulm
- Lefkos Stavros Clinic — Athens
- MTA-SE Cardiovascular Imaging Research Group — Budapest
- Centro Cardiologico Monzino IRCCS, University of Milan — Milan
- Oita University — Ōita
- Amsterdam Universitair Medische Centra — Amsterdam
- Zuyderland Medical Centre — Sittard
- University of Medicine and Pharmacy of Targu Mures — Târgu Mureş
- Seoul National University — Seoul
- Cleveland Clinic Abu Dhabi — Abu Dhabi
Maryland
- NIH National Heart, Lunch, and Blood Institute — Bethesda
Minnesota
- Mayo Clinic — Rochester
Ohio
- Cleveland Clinic Heart and Vascular Institute — Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250,000 participants |
| Start Date | 2016-02-23 |
| Est. Completion | 2030-02 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05169333
The ClinicalTrials.gov registry entry for NCT05169333 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 250,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Oxford, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05169333 reports 20 study locations spanning 4 distinct geographic areas — top geographies include Other, Maryland, Minnesota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05169333 about?
NCT05169333 is a clinical study titled "The Oxford Risk Factors And Non-Invasive Imaging Study". ORFAN is a prospective, multi-centre, multi-ethnic cohort observational study collecting CT scans, biological material and outcomes data, to develop and validate novel biomarkers of cardiometabolic and other disease risk.
What is the current status of trial NCT05169333?
This trial is currently recruiting. The enrollment target is 250,000 participants. The study started on 2016-02-23. Estimated completion is 2030-02.
What conditions does trial NCT05169333 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Cardiovascular Risk Factors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT05169333?
This trial is sponsored by University of Oxford, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05169333 being conducted?
This trial has 20 study locations across Maryland, Minnesota, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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