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NCT06029348 · ClinicalTrials.gov registry record · NA

Cerebrovascular Health and Resilience in Midlife

A NA study of Cardiovascular Diseases and Psychological Stress, sponsored by University of Pittsburgh.

Recruiting
Registry status
NA
Development phase
450
Enrollment target
1
Study location

NCT06029348: Recruiting NA study of Cardiovascular Diseases and Psychological Stress, sponsored by University of Pittsburgh.

NCT06029348 is a NA study of Cardiovascular Diseases and Psychological Stress that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 450 participants, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06029348, a NA study of Cardiovascular Diseases and Psychological Stress, is actively recruiting participants, sponsored by University of Pittsburgh.

RECRUITING
Registry status
NA
Development phase
450 participants
Enrollment target
1
Study location

Study Summary

This study examines cardiovascular responses to a brief psychological challenge under laboratory conditions among adult volunteers. The study volunteers are asked to complete two study sessions. In one session, the volunteers are asked to provide demographic and health-related information via questionnaires and an interview. In that session, volunteers would then be asked to undergo evaluations of their body composition, blood pressure, heart rate, and other signs of cardiovascular function and health. Lastly, volunteers would be asked to take part in a brief and challenging psychological task after a period of rest while cardiovascular activity is measured. In the other session, volunteers are asked to undergo magnetic resonance imaging and to complete neuropsychological tests of memory, attention, and processing speed. In addition to these two sessions, volunteers are asked to complete online questionnaires. The study is designed to examine associations between transient changes in cardiovascular activity induced by the psychological task, measures of overall cardiovascular health, and measures of cerebrovascular health measured by magnetic resonance imaging. Study results are expected to provide new information about the relationships between cardiovascular activity changes to psychological challenges and cardiovascular and cerebrovascular health in adults.

Primary Outcome

The mean SBP from the baseline period will be subtracted from the mean of the task period.

Interventions

  • BEHAVIORAL Paced Auditory Serial Addition Task

Study Locations (1)

Pennsylvania

  • University of Pittsburgh - Pittsburgh

Trial Details

FieldValue
Enrollment Target 450 participants
Start Date 2023-10-17
Est. Completion 2029-06-30
Phase NA
University of Pittsburgh

1,238 total trials

What NCT06029348 shows while recruiting

NCT06029348 is an interventional study that assigns participants to a tested intervention. The registered 450 participants enrollment target is mid-sized for trials with a published cap, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (98% lower).

The record links to 3 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 1 intervention - of which Paced Auditory Serial Addition Task is the first listed.

NCT06029348 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06029348 about?

NCT06029348 is a clinical study titled "Cerebrovascular Health and Resilience in Midlife". This study examines cardiovascular responses to a brief psychological challenge under laboratory conditions among adult volunteers. The study volunteers are asked to complete two study sessions. In one session, the volunteers are asked to provide demographic and health-related information via questi...

What is the current status of trial NCT06029348?

This trial is currently recruiting. It is a NA study. The enrollment target is 450 participants. The study started on 2023-10-17. Estimated completion is 2029-06-30.

What conditions does trial NCT06029348 study?

This clinical trial studies the following conditions: Cardiovascular Diseases, Psychological Stress, Cerebrovascular Disorders.

What interventions are being tested in trial NCT06029348?

The interventions under investigation include: Paced Auditory Serial Addition Task (BEHAVIORAL).

Who is sponsoring clinical trial NCT06029348?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06029348 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiovascular Diseases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06029348's enrollment target sits among peer trials

450 101st of 300 higher than 199 of 300 other Cardiovascular Diseases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06029348, the US trial registry maintained by the National Library of Medicine. NCT06029348 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.