Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING NA

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

NCT03674307 · View on ClinicalTrials.gov ↗

Study Summary

The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER waitlist activation is not inferior to regular (i.e., annual) screening for CAD during wait-listing for the prevention of Major Adverse Cardiac Events. Secondary analyses will assess the impact of screening on the rate of transplantation, and the relative cost-effectiveness of screening.

Interventions

  • OTHER No screening
  • OTHER Regular Screening

Study Locations (20)

Ontario

  • St. Joseph's Healthcare — Hamilton
  • Kingston Health Science Centre — Kingston
  • London Health Science Centre — London
  • The Ottawa Hospital Research Institute — Ottawa
  • University Health Network — Toronto
  • St Michael's Hospital — Toronto

Quebec

  • CHU de Quebec-Universite Laval's L'Hotel-Dieu de Quebec — Laval
  • University of Montreal, Maisonneuve-Rosemont Hospital — Montreal
  • McGill University Health Centre — Montreal
  • Universite de Montreal, Hopital Maisonneuve-Rosemont — Montreal

Other

  • Charité Universitätsmedizin — Berlin
  • Sussex Brighton R&D — Brighton
  • King's College Hospital NHS Foundation Trust — Brixton
  • Epsom and St Helier University Hospitals NHS Trust — Carshalton

Arizona

  • University of Arizona — Tucson

District of Columbia

  • The George Washington University — Washington D.C.

Alberta

  • University of Alberta — Edmonton

British Columbia

  • University of British Columbia — Vancouver

Nova Scotia

  • Dalhousie University — Halifax

Trial Details

FieldValue
Enrollment Target 3,306 participants
Start Date 2018-12-01
Est. Completion 2025-12-31
Phase NA

Sponsor

University of British Columbia

8 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03674307

The ClinicalTrials.gov registry entry for NCT03674307 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,306 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of British Columbia, which has 8 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 2 interventions — of which No screening is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03674307 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Ontario, Quebec, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03674307 about?

NCT03674307 is a clinical study titled "Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates". The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER waitlist activation is not inferior to regular (i.e., annual) screening for...

What is the current status of trial NCT03674307?

This trial is currently recruiting. It is a NA study. The enrollment target is 3,306 participants. The study started on 2018-12-01. Estimated completion is 2025-12-31.

What conditions does trial NCT03674307 study?

This clinical trial studies the following conditions: Cardiovascular Diseases, End Stage Renal Disease, Kidney Transplantation, Dialysis Related Complication. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03674307?

The interventions under investigation include: No screening (OTHER), Regular Screening (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03674307?

This trial is sponsored by University of British Columbia, which has 8 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03674307 being conducted?

This trial has 20 study locations across Arizona, District of Columbia, Alberta, British Columbia, Nova Scotia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial