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NCT04841447 · ClinicalTrials.gov registry record
Membrane Target Detection for Leukemia Treatment
A clinical trial of Hematological Malignancy, sponsored by University of Missouri-Columbia.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT04841447: Recruiting study of Hematological Malignancy, sponsored by University of Missouri-Columbia.
NCT04841447 is a study of Hematological Malignancy that is actively recruiting participants, run by University of Missouri-Columbia. The registered enrollment target is 50 participants, below the 116-participant average among 9 other Hematological Malignancy trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04841447, a study of Hematological Malignancy, is actively recruiting participants, sponsored by University of Missouri-Columbia.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Acute myeloid leukemia (AML) accounts for more than 40% of leukemia mortality in the United States. Each year around ten thousand people die from the disease, most within a few years of diagnosis. Despite advances in our understanding of the disease, few improvements in the therapy of AML have been made. Collecting specimens from the blood and bone marrow will increase understanding of the effect of Dipeptidyl Peptidase-4 (DPP-4) Inhibitors on human AML-SCP to develop individualized therapies. We also found DPP4 is highly expressed in other hematological malignancies in our mouse model, thus we would like to use human samples to investigate the role of DPP4 in hematological malignancy development and the mechanism underlying, especially to deeply understand the role of DDP4 in leukemia.
Primary Outcome
DPP4 inhibitors measured in blood samples will be used in vitro and in vivo a pre-clinical model.
Conditions Studied
Interventions
- OTHER Study sample collection
Study Locations (1)
Missouri
- University of Missouri - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2020-03-20 |
| Est. Completion | 2027-03-20 |
What NCT04841447 shows while recruiting
NCT04841447 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 116-participant average among 9 other Hematological Malignancy trials with a reported enrollment target (57% lower).
The record links to 1 condition, with Hematological Malignancy appearing as the primary indexed condition, and to 1 intervention - of which Study sample collection is the first listed.
NCT04841447 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT04841447 about?
NCT04841447 is a clinical study titled "Membrane Target Detection for Leukemia Treatment". Acute myeloid leukemia (AML) accounts for more than 40% of leukemia mortality in the United States. Each year around ten thousand people die from the disease, most within a few years of diagnosis. Despite advances in our understanding of the disease, few improvements in the therapy of AML have been ...
What is the current status of trial NCT04841447?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2020-03-20. Estimated completion is 2027-03-20.
What conditions does trial NCT04841447 study?
This clinical trial studies the following conditions: Hematological Malignancy.
What interventions are being tested in trial NCT04841447?
The interventions under investigation include: Study sample collection (OTHER).
Who is sponsoring clinical trial NCT04841447?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04841447 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04841447's enrollment target sits among peer trials
50 6th of 9 higher than 4 of 9 other Hematological Malignancy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hematological Malignancy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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