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NCT06064695 · ClinicalTrials.gov registry record · NA

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Myasthenia Gravis

A NA study of Generalized Myasthenia Gravis, sponsored by University of Missouri-Columbia.

Recruiting
Registry status
NA
Development phase
16
Enrollment target
2
Study locations

NCT06064695 is a NA study of Generalized Myasthenia Gravis that is actively recruiting participants, run by University of Missouri-Columbia. The registered enrollment target is 16 participants, below the 131-participant average among 26 other Generalized Myasthenia Gravis trials with a reported enrollment target (88% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06064695, a NA study of Generalized Myasthenia Gravis, is actively recruiting participants, sponsored by University of Missouri-Columbia.

RECRUITING
Registry status
NA
Development phase
16 participants
Enrollment target
2
Study locations

Study Summary

During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on neuromuscular junction (NMJ) transmission and fatigability in adults with Generalized Myasthenia Gravis (gMG). The investigators will also test whether a relationship exists between NMJ transmission dysfunction and fatigability in gMG, which has long been presumed but never directly assessed. Participants will undergo clinical and electrophysiologic testing before and after the WB-EMS Exercise intervention. The WB-EMS Exercise intervention will be delivered 2 times per week for 4 weeks. Long-term follow up is optional. The hypotheses are (a) that the WB-EMS exercise will improve fatigability and NMJ transmission, and (b) that NMJ transmission dysfunction is related to fatigability.

Conditions Studied

Generalized Myasthenia Gravis

Interventions

  • DEVICE Whole-body Electrical Muscle Stimulation Exercise

Study Locations (2)

Kansas

  • University of Kansas Clinical Research Center - Fairway

Missouri

  • NextGen Precision Health Building, Clinical and Translational Science Unit - Columbia

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2023-07-12
Est. Completion 2025-08
Phase NA

Sponsor

University of Missouri-Columbia

291 total trials

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What the Registry Record Tells You About NCT06064695

The ClinicalTrials.gov registry entry for NCT06064695 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 131-participant average among 26 other Generalized Myasthenia Gravis trials with a reported enrollment target (88% lower). The listed sponsor is University of Missouri-Columbia, which has 291 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Generalized Myasthenia Gravis appearing as the primary indexed condition, and to 1 intervention - of which Whole-body Electrical Muscle Stimulation Exercise is the first listed.

NCT06064695 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Kansas, Missouri.

Frequently Asked Questions

What is clinical trial NCT06064695 about?

NCT06064695 is a clinical study titled "Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Myasthenia Gravis". During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on neuromuscular junction (NMJ) transmission and fatigability in adults with Generalized Myasthenia Gravis (gMG). The investigators will also test whether a rela...

What is the current status of trial NCT06064695?

This trial is currently recruiting. It is a NA study. The enrollment target is 16 participants. The study started on 2023-07-12. Estimated completion is 2025-08.

What conditions does trial NCT06064695 study?

This clinical trial studies the following conditions: Generalized Myasthenia Gravis.

What interventions are being tested in trial NCT06064695?

The interventions under investigation include: Whole-body Electrical Muscle Stimulation Exercise (DEVICE).

Who is sponsoring clinical trial NCT06064695?

This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06064695 being conducted?

This trial has 2 study locations across Kansas, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.