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NCT06066710 · ClinicalTrials.gov registry record · Early Phase 1

Propranolol in Primary Progressive Aphasia

A Early Phase 1 study of Aphasia, Primary Progressive, sponsored by University of Missouri-Columbia.

Recruiting
Registry status
Early Phase 1
Development phase
30
Enrollment target
1
Study location

NCT06066710: Recruiting Early Phase 1 study of Aphasia, Primary Progressive, sponsored by University of Missouri-Columbia.

NCT06066710 is a Early Phase 1 study of Aphasia, Primary Progressive that is actively recruiting participants, run by University of Missouri-Columbia. The registered enrollment target is 30 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (43% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06066710, a Early Phase 1 study of Aphasia, Primary Progressive, is actively recruiting participants, sponsored by University of Missouri-Columbia.

RECRUITING
Registry status
Early Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to find out how the language of people with Primary Progressive Aphasia is affected by Propranolol. Propranolol is not FDA approved for the treatment of Primary Progressive Aphasia. Propranolol is FDA approved for the treatment of heart conditions such as blood pressure. This research is being done because there are currently no drug treatment options for language impairments and anxiety often experienced by people with Primary Progressive Aphasia.

Interventions

  • DRUG Placebo
  • DRUG Propranolol
  • DEVICE Magnetic Resonance Imaging (MRI)

Study Locations (1)

Missouri

  • University of Missouri-Columbia - Columbia

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-01-13
Est. Completion 2027-12
Phase Early Phase 1
University of Missouri-Columbia

291 total trials

What NCT06066710 shows while recruiting

NCT06066710 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (43% lower).

The record links to 1 condition, with Aphasia, Primary Progressive appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT06066710 reports a single indexed study location in Missouri.

Frequently Asked Questions

What is clinical trial NCT06066710 about?

NCT06066710 is a clinical study titled "Propranolol in Primary Progressive Aphasia". The purpose of this study is to find out how the language of people with Primary Progressive Aphasia is affected by Propranolol. Propranolol is not FDA approved for the treatment of Primary Progressive Aphasia. Propranolol is FDA approved for the treatment of heart conditions such as blood pressure....

What is the current status of trial NCT06066710?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 30 participants. The study started on 2025-01-13. Estimated completion is 2027-12.

What conditions does trial NCT06066710 study?

This clinical trial studies the following conditions: Aphasia, Primary Progressive.

What interventions are being tested in trial NCT06066710?

The interventions under investigation include: Placebo (DRUG), Propranolol (DRUG), Magnetic Resonance Imaging (MRI) (DEVICE).

Who is sponsoring clinical trial NCT06066710?

This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06066710 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Aphasia, Primary Progressive

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06066710's enrollment target sits among peer trials

30 807th of 2000 higher than 1,075 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06066710, the US trial registry maintained by the National Library of Medicine. NCT06066710 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.