Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Microbial Colonization clinical trials
Every US clinical trial registered for Microbial Colonization — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
21 US clinical trials · 10 currently recruiting
The research picture
Microbial Colonization has 21 registered US clinical trials, 10 of them open to new participants right now — about 48% of the total.
- 10
- recruiting participants now
- 48%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 3
- top sponsor: University of Missouri-Columbia
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Personalized Responses to Dietary Composition Trial 3
Zoe Global Limited
NCT04735835
Assessment of the Ocular Microbiome in Health and Disease
Vanderbilt University Medical Center
NCT05414994
Understanding the Burn Wound Microbiome: Comparing Traditional Wound Cultures to Next Generation Sequencing Technology
The University of Texas Medical Branch, Galveston
NCT05275335
Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract
University of California, Irvine
NCT05603650
Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome
Johns Hopkins University
NCT06283355
Administering NMT to Reestablish Infant Nasal Microbiome Diversity Following Intranasal Mupirocin Treatment
Johns Hopkins University
NCT06805994
Gut Microbiota-dependent Health Impacts of Haskap Berries
Montana State University
NCT06546020
Skin Preparation for Elective Foot and Ankle Surgery
University of Missouri-Columbia
NCT05401292
Microbiome Derived Metabolism and Pharmacokinetics
Rutgers, The State University of New Jersey
NCT05065671
Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement
Case Western Reserve University
NCT06149585
NICU Antibiotics and Outcomes Trial
Michael Morowitz
NCT03997266
Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk
University of Alabama at Birmingham
NCT04325308
Frequent Standardized Oral Care to Improve Health Outcomes in Premature Infants in the Neonatal Intensive Care Unit
University of Florida
NCT05167318
An Examination of Infants' Microbiome, Nutrition, and Development Study.
University of California, Davis
NCT03229863
Effects of Pulse Consumption, Gut Microbiome, and Appetite in Healthy Participants
University of Missouri-Columbia
NCT07043712
Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant
Johns Hopkins University
NCT05695196
Pilot Haskap Metabolite Timing Project
Montana State University
NCT06938386
Dairy Fat and Fermentation Study
Tufts University
NCT05840081
Microbial Colonization in Three Dimensional (3D) Printed Orthodontic Clear Aligners
University of Michigan
NCT07143370
Variability in Microbial Response to Dietary Fiber
University of Missouri-Columbia
NCT06023940
Effects of Intravenous (IV) Omadacycline on Gut Microbiome
Wake Forest University Health Sciences
NCT05515562
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Microbial Colonization Trial Landscape
ClinicalTrials.gov lists 21 US studies indexed under Microbial Colonization, and 10 of those are currently open to recruitment — roughly 48% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Microbial Colonization shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Microbial Colonization is led by University of Missouri-Columbia with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 21 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Microbial Colonization?
PlainTrial tracks 21 US clinical trials for Microbial Colonization, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Microbial Colonization?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.