University of Iowa

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Iowa sits in the top decile of US sponsors by registered trial count (#143 of 15,742 sponsors by registered trial count).

228 total trials 28 currently recruiting 156 completed early-phase tilt top decile by trial count

University of Iowa: 228 sponsored US clinical trials, 28 recruiting.

University of Iowa sponsors 228 registered US clinical trials on ClinicalTrials.gov, 28 of them currently recruiting, and 156 completed. 23 of these trials are in Phase 3-4 (later-stage) and 49 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 6 trials.

Top-decile sponsor footprint

University of Iowa ranks in the top decile of sponsors by registered trial count (#143 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 51/100

156 of 184 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (84.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

228 total, page 1 of 5

RECRUITING

Genetic Risk Factor for Heat Stroke

NCT06847256

RECRUITING NA

Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity

NCT07244809

RECRUITING NA

Robotic-Assisted Versus Manual Electrode Array Insertion

NCT06951594

RECRUITING NA

Effect of Custom Dynamic Orthoses on Forefoot Loading

NCT06710119

RECRUITING Phase 2

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

NCT06405607

RECRUITING NA

E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app

NCT07032350

RECRUITING

PERceptions of Diltiazem Versus ADEnosine for Treatment of Supraventricular Tachycardia in the Emergency Department

NCT07086560

RECRUITING

Aquagenic Wrinkling Prediction

NCT06831110

RECRUITING NA

Outcomes of Limited Postoperative Restrictions Following Sling Placement: A Randomized Controlled Trial

NCT06840093

RECRUITING Phase 2

IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia

NCT06559969

RECRUITING NA

Cognitive Control to Boost Physical Activity Adherence

NCT06338774

RECRUITING NA

The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses

NCT06127316

RECRUITING Early Phase 1

Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

NCT06489249

RECRUITING Early Phase 1

Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation

NCT06499844

RECRUITING Phase 2

177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry

NCT06395402

RECRUITING NA

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

NCT06127264

RECRUITING NA

Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery

NCT06207318

RECRUITING Early Phase 1

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

NCT05461092

RECRUITING Phase 1

Omega-3 Fatty Acid Lipidomics in Diabetes Peripheral Neuropathy

NCT05169060

RECRUITING

Language Outcomes, Mechanisms, and Trajectories in Adults With and Without Developmental Language Disorder

NCT06898671

RECRUITING Phase 2

Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

NCT05239546

RECRUITING

COVID-19 Coagulopathy Extension Study

NCT05334615

RECRUITING

CT-Based Changes in Bone and Marrow Among Patients on Oral Steroids

NCT04518722

RECRUITING Phase 2

MMP-9 Inhibition for Recalcitrant Wet AMD

NCT04504123

RECRUITING

Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease

NCT05707663

RECRUITING NA

Carbon Dioxide (CO2) Chemosensitivity and SUDEP

NCT04134754

RECRUITING NA

The Effects of AFO Heel Height and Stiffness on Gait

NCT04800484

RECRUITING

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

NCT01193088

ACTIVE NOT RECRUITING NA

Pharmacist Intervention to Improve Smoking Cessation

NCT06943287

ACTIVE NOT RECRUITING Phase 4

Pharmacokinetics of Transdermal Metronidazole

NCT05929794

ACTIVE NOT RECRUITING NA

Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD

NCT04861571

ACTIVE NOT RECRUITING NA

Birth to Three - Cavity Free

NCT05756413

ACTIVE NOT RECRUITING NA

Activity and Cancer Survivorship Exercise Pilot

NCT07283029

ACTIVE NOT RECRUITING

Neuroendocrine Tumors - Patient Reported Outcomes

NCT05064150

ACTIVE NOT RECRUITING

Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT

NCT05287204

ACTIVE NOT RECRUITING NA

Telerehabilitation After Shoulder Arthroplasty

NCT05499728

ACTIVE NOT RECRUITING Phase 1

Target Engagement of Terazosin in Healthy Adults

NCT04551040

ACTIVE NOT RECRUITING NA

Cerebellar TDCS for SRPCS Treatment

NCT04760899

ACTIVE NOT RECRUITING NA

Casting vs Bracing for Idiopathic Early-Onset Scoliosis

NCT04500041

ACTIVE NOT RECRUITING NA

Cystoealstometer (Bladder Monitor Device)-Home Use

NCT05232253

ACTIVE NOT RECRUITING Early Phase 1

Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)

NCT04634227

ACTIVE NOT RECRUITING

Effects of Transitional Circulation in ELBW Infants

NCT02016599

NOT YET RECRUITING NA

Dimensional Changes: Randomized Clinical Trial

NCT05684068

NOT YET RECRUITING Early Phase 1

Effect of Terazosin on ATP Levels in People With Amyotrophic Lateral Sclerosis

NCT07224269

COMPLETED NA

Evaluation of a Habit-based Work-up to Support Medication Adherence

NCT06230978

COMPLETED NA

A Pharmacist Intervention to Improve Mother and Child Health

NCT06073054

TERMINATED NA

Wearable Bioimpedance Analyzer for Tracking Body Composition Changes

NCT05986617

COMPLETED NA

Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics

NCT05456295

TERMINATED Phase 4

Pregabalin for Central Sensitization in TKA

NCT05460871

COMPLETED

Reducing ESKAPE Transmission in the Operating Room

NCT06274918

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Phase Distribution

PhaseTrial count
Phase 1 22
Phase 2 27
Phase 3 4
Phase 4 19

What is open in the University of Iowa pipeline

28 recruiting of 228 indexed (12% open); 156 completed (68%).

Phase mix: 23 late (III/IV) vs 49 early (I/II) (early-phase heavy).

Top condition: Healthy (6 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Iowa: open-pipeline peers nationwide

Peers matched on 228 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

University of Iowa sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400 10%12%14%16%18%20% Total trials Recruiting share University of IowaGeorgetown UniversityUniversity Hospitals Cleveland Medical CenterBrown UniversityHenry Ford Health SystemDaiichi SankyoAugusta UniversityNational Institute of Mental Health (NIMH)Friends Research Institute
University of Iowa sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Iowa sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 228 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this University of Iowa page

228 registered trials is a research-attention snapshot, not an endorsement of University of Iowa or any single study.

  • 28 of University of Iowa's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition University of Iowa studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Iowa pipeline card: 228 registered trials from official public datasets.Report a data error.