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NCT06207318 · ClinicalTrials.gov registry record · NA

Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery

A NA study of Coronary Artery Disease and Vascularization, sponsored by University of Iowa.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT06207318: Recruiting NA study of Coronary Artery Disease and Vascularization, sponsored by University of Iowa.

NCT06207318 is a NA study of Coronary Artery Disease and Vascularization that is actively recruiting participants, run by University of Iowa. The registered enrollment target is 30 participants, below the 1,287-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06207318, a NA study of Coronary Artery Disease and Vascularization, is actively recruiting participants, sponsored by University of Iowa.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

Heart disease is the leading cause of death globally, accounting for 16% of the world's total deaths. The number of cases is expected to increase as our population ages. Heart disease also results in large economic burden. It costs the United States about $219 billion per year. Some patients have symptoms that aren't helped by drugs or other medical treatments. These patients will need a surgery that is called cardiac artery bypass graft (CABG) surgery. CABG helps to improve chest pain which is one of the most common complaints of heart disease, and has life-prolonging potential. A limitation of CABG is that it results in increased inflammation. These patients also report high levels of anxiety and depression. Depression and anxiety in the several days surrounding surgery are related to several important things. These include worse health outcomes, worse quality of life, increased risk of death, and increased health care cost. Acceptance and Commitment Therapy (ACT) is a kind of therapy. ACT is adaptable, easy to access, and effective in brief formats. ACT has been gaining evidence for its use in many patient samples. Few studies have used ACT with heart disease patients. No known studies currently exist that have used ACT within the few days surrounding CABG surgery. To address this need, the investigators will conduct a two-arm feasibility randomized control trial (RCT). Patients will be randomized to one of two groups. The first group will complete a brief, 2-session telehealth ACT intervention. The second group will be a control group. The control will consist of treatment as usual. The investigators will evaluate the feasibility of this brief ACT intervention delivered in the peri-operative period. The investigators will also examine preliminary efficacy of the ACT intervention. The investigators will examine anxiety, depression, psychological inflexibility, well-being, and cardiovascular health-related quality of life. The investigators will also examine the i

Primary Outcome

The TFA is comprised of seven constructs: affective attitude, burden, ethicality, perceived effectiveness, intervention coherence, self-efficacy, and opportunity costs, and also includes an overall acceptability rating. The TFA can be used to generate a single acceptability score and/or to assess the unique domains of acceptability included in the model. Scale scores range from minimum values of 7, and maximum values of 35, with higher scores indicating higher acceptability.

Interventions

  • BEHAVIORAL Acceptance and commitment therapy

Study Locations (1)

Iowa

  • University of Iowa Hospitals and Clinics - Iowa City

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2024-02-12
Est. Completion 2025-12
Phase NA
University of Iowa

228 total trials

What NCT06207318 shows while recruiting

NCT06207318 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,287-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (98% lower).

The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 1 intervention - of which Acceptance and commitment therapy is the first listed.

NCT06207318 reports a single indexed study location in Iowa.

Frequently Asked Questions

What is clinical trial NCT06207318 about?

NCT06207318 is a clinical study titled "Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery". Heart disease is the leading cause of death globally, accounting for 16% of the world's total deaths. The number of cases is expected to increase as our population ages. Heart disease also results in large economic burden. It costs the United States about $219 billion per year. Some patients have sy...

What is the current status of trial NCT06207318?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2024-02-12. Estimated completion is 2025-12.

What conditions does trial NCT06207318 study?

This clinical trial studies the following conditions: Coronary Artery Disease, Vascularization.

What interventions are being tested in trial NCT06207318?

The interventions under investigation include: Acceptance and commitment therapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT06207318?

This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06207318 being conducted?

This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Coronary Artery Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06207318's enrollment target sits among peer trials

30 198th of 219 higher than 17 of 219 other Coronary Artery Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Coronary Artery Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06207318, the US trial registry maintained by the National Library of Medicine. NCT06207318 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.