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NCT06847256 · ClinicalTrials.gov registry record
Genetic Risk Factor for Heat Stroke
A clinical trial of Dehydration and Carrier State, sponsored by University of Iowa.
- Recruiting
- Registry status
- 200
- Enrollment target
- 1
- Study location
NCT06847256: Recruiting study of Dehydration and Carrier State, sponsored by University of Iowa.
NCT06847256 is a study of Dehydration and Carrier State that is actively recruiting participants, run by University of Iowa. The registered enrollment target is 200 participants, above the 48-participant average among 20 other Dehydration trials with a reported enrollment target (317% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06847256, a study of Dehydration and Carrier State, is actively recruiting participants, sponsored by University of Iowa.
- RECRUITING
- Registry status
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study is to examine the effect of the Cystic Fibrosis (CF) Carrier state on the risk for dehydration and other CF-specific fluid-and-electrolyte disorders in male and female adults. The primary aim of the study is to estimate the risk of electrolyte disorders attributable to the CF carrier state in a genotyped cohort. This will be accomplished with two smaller projects- Aim 1 and Aim 2. Aim 1 will consist of 100 CF Carriers and 100 age- and sex-matched controls. Participants in this aim will be asked to complete a Participant Info and Temperature Survey consisting of questions about race, ethnicity, medical history, and how they experience heat. Aim 2 will consist of a subset of 25 CF Carriers and 25 age- and sex-matched controls from Aim 1. Participants in this aim will be scheduled for a visit to complete a heat challenge. At this visit, they will also complete the Participant Info and Temperature Survey. They will also sit in a sauna at 62 - 63 degrees Celsius for 45 minutes.
Primary Outcome
Individual and composite scores for 5 components of the Temperature Sensitivity Survey (Heat- and Activity-Induced Autonomic Thermoregulation; Heat-Induced Behavioral Thermoregulation; Heat Perception; and Heat- and Activity-Induced Fatigue). For these 5 components, there are a total of 25 questions. All questions are on a 7-point scale, with the highest representing the most sensitive to heat and the lowest being the least sensitive. We will add up the scores for each question to arrive at a co
Conditions Studied
Interventions
- PROCEDURE Heat Challenge
Study Locations (1)
Iowa
- University of Iowa Health Care - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-11-19 |
| Est. Completion | 2026-03 |
What NCT06847256 shows while recruiting
NCT06847256 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 48-participant average among 20 other Dehydration trials with a reported enrollment target (317% higher).
The record links to 3 conditions, with Dehydration appearing as the primary indexed condition, and to 1 intervention - of which Heat Challenge is the first listed.
NCT06847256 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT06847256 about?
NCT06847256 is a clinical study titled "Genetic Risk Factor for Heat Stroke". The goal of this observational study is to examine the effect of the Cystic Fibrosis (CF) Carrier state on the risk for dehydration and other CF-specific fluid-and-electrolyte disorders in male and female adults. The primary aim of the study is to estimate the risk of electrolyte disorders attribut...
What is the current status of trial NCT06847256?
This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2025-11-19. Estimated completion is 2026-03.
What conditions does trial NCT06847256 study?
This clinical trial studies the following conditions: Dehydration, Carrier State, Heat Stroke.
What interventions are being tested in trial NCT06847256?
The interventions under investigation include: Heat Challenge (PROCEDURE).
Who is sponsoring clinical trial NCT06847256?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06847256 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dehydration
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06847256's enrollment target sits among peer trials
200 1st of 20 higher than 20 of 20 other Dehydration trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dehydration trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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