Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Tooth Loss: later-stage trial registry
5 of 12 indexed Tooth Loss trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,429 of 28,707 conditions by registered trial count.
12 US clinical trials · 5 currently recruiting · #1,429 of 28,707 conditions by registered trial count
Tooth Loss: 12 US clinical trials tracked, 5 recruiting.
Tooth Loss is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is ZimVie, running 2 of these trials.
Enrollment posture brief
Registry condition tooth-loss
OPEN 5 | RECR 42% | LATE 3 | EARLY 0 | RANK #1429 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adiposity (42% recruiting · 12 trials)
Tooth Loss lists 5 open slots (42% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Tooth Loss on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Tooth Loss is recruiting below its size-band peers.
5 of 12 indexed trials (41.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Tooth Loss research.
ZimVie accounts for 2 of 12 trials (16.7%). 10 distinct sponsors appear on at least one study for this condition label.
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Most Tooth Loss trials plan to enrol fewer than 100 people.
Median target enrolment is 50 among the 12 trials that report a genuine target (sentinel values excluded). 10 of those (83.3%) plan for fewer than 100 participants.
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Tooth Loss splits between interventional and observational designs.
7 interventional and 5 observational studies make up this index (58.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
12 total, page 1 of 1
5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece.
CeraRoot SL
NCT06287346
A Clinical Study of the TSX Dental Implant System (Xpresso)
ZimVie
NCT06571812
An Observational Study of the T3 Pro Dental Implant System
ZimVie
NCT05498662
Clinical Performance of Nobel N1 System
Louisiana State University Health Sciences Center in New Orleans
NCT07280260
Peri-implant Mucosal Changes Over Time Following Implant Provisional Removal in the Esthetic Zone
Loma Linda University
NCT06783595
Bone Level Tapered Multi-Center Study
Institut Straumann
NCT02569671
Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft
UConn Health
NCT04550689
Undiagnosed Diabetes in a Dental Setting
Columbia University
NCT01711385
Initial Stability of Posterior Maxillary Implants With Bicortical Fixation
University of Minnesota
NCT01237184
Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®
University of Iowa
NCT03659617
Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
University of Iowa
NCT02450383
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
Gustavo Avila-Ortiz DDS, MS, PhD
NCT02980211
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Tooth Loss records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Tooth Loss trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Tooth Loss page
12 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Tooth Loss trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- ZimVie sponsors the most Tooth Loss trials on record, review their full trial history before evaluating a specific study. See ZimVie's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Tooth Loss condition card totals 12 registered trials; most-linked intervention Enhanced intervention; top US site state Iowa. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.