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ClinicalTrials.gov 5 recruiting now official registry

Tooth Loss clinical trials

5 of 12 indexed Tooth Loss trials are currently recruiting.

12 US clinical trials · 5 currently recruiting

Tooth Loss is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is ZimVie, running 2 of these trials.

The research picture

Tooth Loss has 12 registered US clinical trials, 5 of them open to new participants right now, about 42% of the total.

5
recruiting participants now
42%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: ZimVie
Phase 43

Active & Recent Trials

12 total, page 1 of 1

RECRUITING 652 participants

5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece.

CeraRoot SL

NCT06287346

RECRUITING 62 participants

A Clinical Study of the TSX Dental Implant System (Xpresso)

ZimVie

NCT06571812

RECRUITING 60 participants

An Observational Study of the T3 Pro Dental Implant System

ZimVie

NCT05498662

RECRUITING Phase 4 50 participants

Clinical Performance of Nobel N1 System

Louisiana State University Health Sciences Center in New Orleans

NCT07280260

RECRUITING 34 participants

Peri-implant Mucosal Changes Over Time Following Implant Provisional Removal in the Esthetic Zone

Loma Linda University

NCT06783595

ACTIVE NOT RECRUITING NA 53 participants

Bone Level Tapered Multi-Center Study

Institut Straumann

NCT02569671

ACTIVE NOT RECRUITING NA 12 participants

Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft

UConn Health

NCT04550689

COMPLETED NA 101 participants

Undiagnosed Diabetes in a Dental Setting

Columbia University

NCT01711385

COMPLETED 45 participants

Initial Stability of Posterior Maxillary Implants With Bicortical Fixation

University of Minnesota

NCT01237184

COMPLETED NA 39 participants

Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®

University of Iowa

NCT03659617

COMPLETED Phase 4 20 participants

Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness

University of Iowa

NCT02450383

COMPLETED Phase 4 17 participants

Treatment of Post-Extraction Dehisced Socket - A Case Series Study

Gustavo Avila-Ortiz DDS, MS, PhD

NCT02980211

Phase Distribution

PhaseTrial count
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Tooth Loss Trial Landscape

12 indexed Tooth Loss studies · 5 recruiting (42%).

Phase mix: 3 late (III/IV) vs 0 early (I/II).

Top sponsor: ZimVie (2 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Tooth Loss?

PlainTrial tracks 12 US clinical trials for Tooth Loss, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Tooth Loss?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.