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Tooth Loss clinical trials
5 of 12 indexed Tooth Loss trials are currently recruiting.
12 US clinical trials · 5 currently recruiting
Tooth Loss is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is ZimVie, running 2 of these trials.
The research picture
Tooth Loss has 12 registered US clinical trials, 5 of them open to new participants right now, about 42% of the total.
- 5
- recruiting participants now
- 42%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: ZimVie
Active & Recent Trials
12 total, page 1 of 1
5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece.
CeraRoot SL
NCT06287346
A Clinical Study of the TSX Dental Implant System (Xpresso)
ZimVie
NCT06571812
An Observational Study of the T3 Pro Dental Implant System
ZimVie
NCT05498662
Clinical Performance of Nobel N1 System
Louisiana State University Health Sciences Center in New Orleans
NCT07280260
Peri-implant Mucosal Changes Over Time Following Implant Provisional Removal in the Esthetic Zone
Loma Linda University
NCT06783595
Bone Level Tapered Multi-Center Study
Institut Straumann
NCT02569671
Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft
UConn Health
NCT04550689
Undiagnosed Diabetes in a Dental Setting
Columbia University
NCT01711385
Initial Stability of Posterior Maxillary Implants With Bicortical Fixation
University of Minnesota
NCT01237184
Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®
University of Iowa
NCT03659617
Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
University of Iowa
NCT02450383
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
Gustavo Avila-Ortiz DDS, MS, PhD
NCT02980211
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Tooth Loss Trial Landscape
12 indexed Tooth Loss studies · 5 recruiting (42%).
Phase mix: 3 late (III/IV) vs 0 early (I/II).
Top sponsor: ZimVie (2 trials), 9 others listed. 12 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Tooth Loss?
PlainTrial tracks 12 US clinical trials for Tooth Loss, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Tooth Loss?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.