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NCT05684068 · ClinicalTrials.gov registry record · NA
Dimensional Changes: Randomized Clinical Trial
A NA study, sponsored by University of Iowa.
- Not yet
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT05684068: Clinical Trial NA study, sponsored by University of Iowa.
NCT05684068 is a NA study that has not yet begun recruiting, run by University of Iowa. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05684068, a NA study, has not yet begun recruiting, sponsored by University of Iowa.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to evaluate the dimensional changes in the short and long-term in patients with thin gum tissues who have gum grafts placed on either denuded bone or gum grafts placed on a bone with some tissues remaining. The main question this study aims to answer is: \- Does the placement of free-epithelized gingival grafts (gum grafts) on full thickness bed preparation (having all of the tissue removed from the bone) lead to similar clinical, digital, and patient-related outcomes and measurements over a period of 12 months versus split thickness bed preparation (where a small layer of tissue is left over the bone) in patients with thin gum tissue phenotypes (gum tissue is generally less than 1.5 millimeters) who are in need of soft tissue augmentation procedures? Participants will be asked to attend 8 visits, which include: (i) screening visit, (ii) prophylaxis visit, (iii) random assignment to Group A or Group B along with surgery and digital data collection, (iv) 2-week post-operative visit, (v) 6-week post-operative visit, (vi) 3-month follow-up visit, (vii) 6-month follow-up visit, (viii) 12-month follow-up visit. Also, Group A will have a free epithelialized gingival/mucosal graft (gum graft) placed on full thickness periosteal bed preparation where all of the tissue was removed (test group). Group B will have a free epithelialized gingival/mucosal graft (gum graft) on split thickness periosteal bed preparation where only a portion of the tissue was removed (control group). Researchers will compare Group A and Group B to see if there is a difference in clinical, digital, and patient-related outcomes and measurements over a period of 12 months.
Primary Outcome
Tissue changes will be assessed in millimeters and percentage.
Interventions
- PROCEDURE Gum Graft Placed on Denuded Bone
- PROCEDURE Gum Graft Placed on Split Thickness Periosteal Bed Preparation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2028-08 |
| Est. Completion | 2031-03 |
| Phase | NA |
What is known before NCT05684068 opens enrollment
NCT05684068 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Gum Graft Placed on Denuded Bone is the first listed.
NCT05684068 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05684068 about?
NCT05684068 is a clinical study titled "Dimensional Changes: Randomized Clinical Trial". The goal of this clinical trial is to evaluate the dimensional changes in the short and long-term in patients with thin gum tissues who have gum grafts placed on either denuded bone or gum grafts placed on a bone with some tissues remaining. The main question this study aims to answer is: \- Does ...
What is the current status of trial NCT05684068?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2028-08. Estimated completion is 2031-03.
What interventions are being tested in trial NCT05684068?
The interventions under investigation include: Gum Graft Placed on Denuded Bone (PROCEDURE), Gum Graft Placed on Split Thickness Periosteal Bed Preparation (PROCEDURE).
Who is sponsoring clinical trial NCT05684068?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05684068's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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