University of Iowa

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Iowa sits in the top decile of US sponsors by registered trial count (#143 of 15,742 sponsors by registered trial count).

228 total trials 28 currently recruiting 156 completed early-phase tilt top decile by trial count

University of Iowa: 228 sponsored US clinical trials, 28 recruiting.

University of Iowa sponsors 228 registered US clinical trials on ClinicalTrials.gov, 28 of them currently recruiting, and 156 completed. 23 of these trials are in Phase 3-4 (later-stage) and 49 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 6 trials.

Top-decile sponsor footprint

University of Iowa ranks in the top decile of sponsors by registered trial count (#143 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 51/100

156 of 184 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (84.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

228 total, page 2 of 5

TERMINATED NA

Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation

NCT05330702

COMPLETED NA

Feasibility, Acceptability, and Preliminary Efficacy of a Remotely-delivered Health Coaching Intervention for Cancer Survivors

NCT07026214

COMPLETED NA

Comparing Relative Strengths of Statistical Associations Between Psychological Traits and Vaccination-Related Outcomes I

NCT07172074

COMPLETED NA

Restoring Glycocalyx Thickness in Older Adults to Improve Vascular Function

NCT06071728

COMPLETED NA

Cerebellar tDCS and Balance Training in PwMS

NCT04391023

COMPLETED NA

Feasibility, Acceptability, and Efficacy of the Sleep Move Stand Study

NCT05498415

TERMINATED Phase 1

A Safety Study Adding Niraparib and Dostarlimab to Radiation Therapy for Rectal Cancers

NCT04926324

COMPLETED NA

Use of Two Dissolvable Therapeutics Under Removable Partial Dentures

NCT05441527

COMPLETED NA

Transcranial Direct Current Stimulation (tDCS) for Post COVID-19 Fatigue

NCT04876417

COMPLETED NA

OPTIMAL in NH Residents With Dementia

NCT05255068

COMPLETED NA

Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics

NCT05209360

COMPLETED NA

The Oral Microbiome in OSCC

NCT04925700

COMPLETED NA

MomMoodBooster VA Program

NCT05196152

COMPLETED Phase 4

Cool vs Room-temperature Artificial Tears

NCT05832996

COMPLETED NA

iWalk Hands Free Crutch

NCT04978363

COMPLETED

Mobile-health Approach to Gather Clinical Information From Patients Following Hospital Discharge

NCT04709939

TERMINATED NA

Effectiveness of GentleWave on the Healing of Apical Periodontitis: A Prospective Cohort Study

NCT04966169

COMPLETED Early Phase 1

Sympathetic Regulation of Large Artery Stiffness in Humans With ISH

NCT04423627

COMPLETED NA

Iterative Design of Custom Dynamic Orthoses

NCT04800510

COMPLETED NA

Visualizing Dermal Micropores With OCT

NCT04867733

COMPLETED NA

Effects of Malleo-Lok Stiffness on Lower Limb Mechanics

NCT04806100

COMPLETED

Symptom-Based Markers for COVID-19 Transmission

NCT04665245

TERMINATED Phase 1

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

NCT04108481

COMPLETED NA

4 mA tDCS, Estrogen, and Leg Muscle Fatigability

NCT04471805

COMPLETED NA

Medication Empowerment and Deprescription for Safety (MEDS) Study

NCT04612166

COMPLETED NA

INcreasing Steps in PREgnancy Study

NCT05455008

COMPLETED NA

Efficacy of Brief Acceptance and Commitment Therapy (ACT) for Perinatal Anxiety

NCT03837392

COMPLETED Phase 4

Covid-19 Associated Coagulopathy

NCT04360824

COMPLETED NA

Acceptance and Commitment Therapy Delivered by Automated Software Messaging

NCT04329897

COMPLETED NA

The Impact of CRRT Modality on Filter Life

NCT04762524

COMPLETED Phase 4

Nasal Decolonization for Orthopedic Trauma Patients

NCT04146116

COMPLETED NA

Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress

NCT04562896

COMPLETED NA

Cerebral Blood Flow and tDCS

NCT04033133

COMPLETED NA

tDCS and Glucose Uptake in Leg Muscles

NCT04016844

TERMINATED

SCANREP: Reliability of 3D Lower Limb Scanning

NCT04032041

COMPLETED

Iowa Cochlear Implant Clinical Research Center Study of SSD Using Med-El Cochlear Implants

NCT03929809

COMPLETED NA

Residential MapTrek- Increasing Physical Activity Among Older Adults in a Residential-Living

NCT04041869

COMPLETED NA

Inorganic Nitrate and OSA

NCT03930563

COMPLETED NA

Increasing Steps Per Day in Rural Veterans

NCT03930238

COMPLETED NA

Impact of Transcranial Direct Current Stimulation Intensity on Leg Muscle Fatigability in Healthy Adults

NCT04321304

COMPLETED Phase 4

Effect of Exercise on Indocyanine Green (ICG) Lymphography Imaging

NCT03584633

COMPLETED NA

tDCS to Lower Neuropathic Pain and Fatigue in People With Multiple Sclerosis

NCT03870048

COMPLETED NA

Listening Visits for Emotionally Distressed Mothers of Hospitalized Newborns

NCT03704948

COMPLETED NA

Pilot Testing for Midline Measuring Device

NCT04883060

COMPLETED NA

Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®

NCT03659617

COMPLETED NA

Hyperglycemia, Exercise, and Endothelial Function

NCT03651713

COMPLETED NA

Micropore Closure Kinetics at Various Body Sites

NCT03657277

COMPLETED Early Phase 1

Angiotensin II and Chronic Inflammation in Persistent Microvascular Dysfunction Following Preeclampsia

NCT03482440

COMPLETED NA

Precision-Based Approach to Matching Evidence-Based Interventions to Students With Externalizing Behaviors

NCT05752942

COMPLETED NA

Antegrade Versus Retrograde IV for Blood Draws

NCT03533777

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Phase Distribution

PhaseTrial count
Phase 1 22
Phase 2 27
Phase 3 4
Phase 4 19

What is open in the University of Iowa pipeline

28 recruiting of 228 indexed (12% open); 156 completed (68%).

Phase mix: 23 late (III/IV) vs 49 early (I/II) (early-phase heavy).

Top condition: Healthy (6 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Iowa: open-pipeline peers nationwide

Peers matched on 228 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

University of Iowa sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400 10%12%14%16%18%20% Total trials Recruiting share University of IowaGeorgetown UniversityUniversity Hospitals Cleveland Medical CenterBrown UniversityHenry Ford Health SystemDaiichi SankyoAugusta UniversityNational Institute of Mental Health (NIMH)Friends Research Institute
University of Iowa sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Iowa sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 228 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this University of Iowa page

228 registered trials is a research-attention snapshot, not an endorsement of University of Iowa or any single study.

  • 28 of University of Iowa's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition University of Iowa studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Iowa pipeline card: 228 registered trials from official public datasets.Report a data error.