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NCT04551040 · ClinicalTrials.gov registry record · Phase 1
Target Engagement of Terazosin in Healthy Adults
A Phase 1 study of Healthy, sponsored by University of Iowa.
- Active
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT04551040: Active Phase 1 study of Healthy, sponsored by University of Iowa.
NCT04551040 is a Phase 1 study of Healthy that is active but no longer recruiting, run by University of Iowa. The registered enrollment target is 18 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04551040, a Phase 1 study of Healthy, is active but no longer recruiting, sponsored by University of Iowa.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to assess the target engagement of Terazosin (TZ) in a single cohort of 6 healthy adult participants. During the study participants will undergo PET/CT scans, 7-Tesla MRI scans, blood draws, and an optional lumbar puncture (LP.)
Primary Outcome
Use of FDG PET to quantify glycolysis in the brain at baseline prior to initiation of terazosin
Conditions Studied
Interventions
- DRUG Terazosin
Study Locations (1)
Iowa
- University of Iowa Hospitals and Clinics - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2021-03-26 |
| Est. Completion | 2025-06-30 |
| Phase | Phase 1 |
What the registry record for NCT04551040 still lists
NCT04551040 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Terazosin is the first listed.
NCT04551040 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT04551040 about?
NCT04551040 is a clinical study titled "Target Engagement of Terazosin in Healthy Adults". The purpose of the study is to assess the target engagement of Terazosin (TZ) in a single cohort of 6 healthy adult participants. During the study participants will undergo PET/CT scans, 7-Tesla MRI scans, blood draws, and an optional lumbar puncture (LP.)
What is the current status of trial NCT04551040?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2021-03-26. Estimated completion is 2025-06-30.
What conditions does trial NCT04551040 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT04551040?
The interventions under investigation include: Terazosin (DRUG).
Who is sponsoring clinical trial NCT04551040?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04551040 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04551040's enrollment target sits among peer trials
18 904th of 1090 higher than 163 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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