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NCT01193088 · ClinicalTrials.gov registry record
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
A clinical trial of Charcot-Marie-Tooth Disease, Type Ia (Disorder) and HMSN, sponsored by University of Iowa.
- Recruiting
- Registry status
- 1,050
- Enrollment target
- 20
- Study locations
NCT01193088: Recruiting study of Charcot-Marie-Tooth Disease, Type Ia (Disorder) and HMSN, sponsored by University of Iowa.
NCT01193088 is a study of Charcot-Marie-Tooth Disease, Type Ia (Disorder) and HMSN that is actively recruiting participants, run by University of Iowa. The registered enrollment target is 1,050 participants. The trial reports 20 study locations across 18 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01193088, a study of Charcot-Marie-Tooth Disease, Type Ia (Disorder) and HMSN, is actively recruiting participants, sponsored by University of Iowa.
- RECRUITING
- Registry status
- 1,050 participants
- Enrollment target
- 20
- Study locations
Study Summary
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
Primary Outcome
While the same genetic change - an extra copy of PMP22 - causes CMT1A by definition, it is unclear why some people have more severe symptoms and some have less severe. We are looking for genetic modifiers - changes in the DNA that may be causing the differences in symptoms.
Conditions Studied
Study Locations (20)
California
- Cedars-Sinai Medical Center - Los Angeles
- Stanford University - Palo Alto
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
- University of Pennsylvania - Philadelphia
Colorado
- University of Colorado Hospital - Aurora
Connecticut
- Connecticut Children's Medical Center - Hartford
Florida
- University of Miami - Miami
Iowa
- University of Iowa - Iowa City
Maryland
- Johns Hopkins University - Baltimore
Massachusetts
- Harvard/Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,050 participants |
| Start Date | 2010-05 |
| Est. Completion | 2026-12 |
What NCT01193088 shows while recruiting
NCT01193088 is an observational study that tracks outcomes without assigning an intervention. Its 1,050 participants enrollment target places it among the larger protocols in the corpus.
The record links to 2 conditions, with Charcot-Marie-Tooth Disease, Type Ia (Disorder) appearing as the primary indexed condition, and to 0 interventions.
NCT01193088 names 20 study sites across 18 states, led by California, Pennsylvania, Colorado.
Frequently Asked Questions
What is clinical trial NCT01193088 about?
NCT01193088 is a clinical study titled "Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2". This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
What is the current status of trial NCT01193088?
This trial is currently recruiting. The enrollment target is 1,050 participants. The study started on 2010-05. Estimated completion is 2026-12.
What conditions does trial NCT01193088 study?
This clinical trial studies the following conditions: Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN.
Who is sponsoring clinical trial NCT01193088?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01193088 being conducted?
This trial has 20 study locations across California, Colorado, Connecticut, Florida, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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