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Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
NCT01193088 · View on ClinicalTrials.gov ↗
Study Summary
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
Conditions Studied
Study Locations (20)
California
- Cedars-Sinai Medical Center — Los Angeles
- Stanford University — Palo Alto
Pennsylvania
- Children's Hospital of Philadelphia — Philadelphia
- University of Pennsylvania — Philadelphia
Colorado
- University of Colorado Hospital — Aurora
Connecticut
- Connecticut Children's Medical Center — Hartford
Florida
- University of Miami — Miami
Iowa
- University of Iowa — Iowa City
Maryland
- Johns Hopkins University — Baltimore
Massachusetts
- Harvard/Massachusetts General Hospital — Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,050 participants |
| Start Date | 2010-05 |
| Est. Completion | 2026-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01193088
The ClinicalTrials.gov registry entry for NCT01193088 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,050 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Iowa, which has 156 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Charcot-Marie-Tooth Disease, Type Ia (Disorder) appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01193088 reports 20 study locations spanning 18 distinct geographic areas — top geographies include California, Pennsylvania, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01193088 about?
NCT01193088 is a clinical study titled "Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2". This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
What is the current status of trial NCT01193088?
This trial is currently recruiting. The enrollment target is 1,050 participants. The study started on 2010-05. Estimated completion is 2026-12.
What conditions does trial NCT01193088 study?
This clinical trial studies the following conditions: Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT01193088?
This trial is sponsored by University of Iowa, which has 156 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01193088 being conducted?
This trial has 20 study locations across California, Colorado, Connecticut, Florida, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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