Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 4

Pharmacokinetics of Transdermal Metronidazole

NCT05929794 · View on ClinicalTrials.gov ↗

Study Summary

This is a crossover pharmacokinetic clinical study in healthy volunteers to compare metronidazole delivery through skin when a gel or cream metronidazole product is applied to skin treated with a micropatch.

Conditions Studied

Interventions

  • DRUG Metronidazole 0.75% Topical Gel
  • DRUG Metronidazole 0.75% Topical Cream
  • DIAGNOSTIC_TEST Transdermal water loss measurement
  • DIAGNOSTIC_TEST Electrical Resistance
  • DIAGNOSTIC_TEST Skin color measurement

Study Locations (1)

Iowa

  • University of Iowa — Iowa City

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2024-02-26
Est. Completion 2026-12
Phase Phase 4

Sponsor

University of Iowa

156 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05929794

The ClinicalTrials.gov registry entry for NCT05929794 describes a study currently listed as active not recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Iowa, which has 156 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 5 interventions — of which Metronidazole 0.75% Topical Gel is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05929794 reports 1 study location spanning 1 distinct geographic area — top geographies include Iowa. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05929794 about?

NCT05929794 is a clinical study titled "Pharmacokinetics of Transdermal Metronidazole". This is a crossover pharmacokinetic clinical study in healthy volunteers to compare metronidazole delivery through skin when a gel or cream metronidazole product is applied to skin treated with a micropatch.

What is the current status of trial NCT05929794?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2024-02-26. Estimated completion is 2026-12.

What conditions does trial NCT05929794 study?

This clinical trial studies the following conditions: Healthy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05929794?

The interventions under investigation include: Metronidazole 0.75% Topical Gel (DRUG), Metronidazole 0.75% Topical Cream (DRUG), Transdermal water loss measurement (DIAGNOSTIC_TEST), Electrical Resistance (DIAGNOSTIC_TEST), Skin color measurement (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05929794?

This trial is sponsored by University of Iowa, which has 156 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05929794 being conducted?

This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial