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NCT04500041 · ClinicalTrials.gov registry record · NA
Casting vs Bracing for Idiopathic Early-Onset Scoliosis
A NA study of Scoliosis Idiopathic and Early-Onset Scoliosis Deformity of Spine, sponsored by University of Iowa.
- Active
- Registry status
- NA
- Development phase
- 71
- Enrollment target
- 20
- Study locations
NCT04500041: Active NA study of Scoliosis Idiopathic and Early-Onset Scoliosis Deformity of Spine, sponsored by University of Iowa.
NCT04500041 is a NA study of Scoliosis Idiopathic and Early-Onset Scoliosis Deformity of Spine that is active but no longer recruiting, run by University of Iowa. The registered enrollment target is 71 participants, below the 290-participant average among 5 other Scoliosis Idiopathic trials with a reported enrollment target (76% lower). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04500041, a NA study of Scoliosis Idiopathic and Early-Onset Scoliosis Deformity of Spine, is active but no longer recruiting, sponsored by University of Iowa.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 71 participants
- Enrollment target
- 20
- Study locations
Study Summary
Comparison of casting and bracing for the treatment of idiopathic early onset scoliosis
Primary Outcome
Resolution - curve improvement to \<15 degrees (as measured on 2 consecutive radiographs) Failure 1. Initial Cobb 20-50° (inclusive): curve progression of ≥20° resulting in a curve ≥50° 2. Initial Cobb \>50°: curve progression of ≥20° Palliation - 2 years of treatment without resolution or failure
Conditions Studied
Interventions
- PROCEDURE Casting
- DEVICE Bracing
Study Locations (20)
Illinois
- Lurie Children's Hospital of Chicago - Chicago
- Shriners Hospitals for Children - Chicago - Chicago
Missouri
- Children's Mercy Kansas City - Kansas City
- St. Louis Children's Hospital/Washington University - St Louis
North Carolina
- University of North Carolina Chapel Hill - Chapel Hill
- Duke University Medical Center - Durham
Oregon
- Doernbecher Children's Hospital / OHSU - Portland
- Shriners Hospitals for Children - Portland - Portland
Pennsylvania
- Children's Hospital of Pennsylvania - Philadelphia
- Shriners Hospitals for Children - Philadelphia - Philadelphia
Arkansas
- Arkansas Children's Hospital - Little Rock
Colorado
- Children's Hospital Colorado - Aurora
Delaware
- Nemours/Alfred I. duPont Hospital for Children - Wilmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 71 participants |
| Start Date | 2021-02-09 |
| Est. Completion | 2026-09-30 |
| Phase | NA |
What the registry record for NCT04500041 still lists
NCT04500041 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 71 participants, a relatively small participant target, below the 290-participant average among 5 other Scoliosis Idiopathic trials with a reported enrollment target (76% lower).
The record links to 2 conditions, with Scoliosis Idiopathic appearing as the primary indexed condition, and to 2 interventions - of which Casting is the first listed.
NCT04500041 names 20 study sites across 15 states, led by Illinois, Missouri, North Carolina.
Frequently Asked Questions
What is clinical trial NCT04500041 about?
NCT04500041 is a clinical study titled "Casting vs Bracing for Idiopathic Early-Onset Scoliosis". Comparison of casting and bracing for the treatment of idiopathic early onset scoliosis
What is the current status of trial NCT04500041?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 71 participants. The study started on 2021-02-09. Estimated completion is 2026-09-30.
What conditions does trial NCT04500041 study?
This clinical trial studies the following conditions: Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine.
What interventions are being tested in trial NCT04500041?
The interventions under investigation include: Casting (PROCEDURE), Bracing (DEVICE).
Who is sponsoring clinical trial NCT04500041?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04500041 being conducted?
This trial has 20 study locations across Arkansas, Colorado, Delaware, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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