National Institute on Drug Abuse (NIDA)

335 total trials 14 currently recruiting 292 completed

National Institute on Drug Abuse (NIDA) sponsors 335 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 292 completed. 30 of these trials are in Phase 3-4 (later-stage) and 202 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cocaine-Related Disorders, with 17 trials.

Trial Pipeline

335 total, page 3 of 7

TERMINATED Phase 1

Ph1 Marinol Interaction Study - Part 1 - 1

NCT00438139

COMPLETED NA

The Neural Basis of Cue-Elicited Cigarette Craving and Its Control

NCT01048957

COMPLETED NA

Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia

NCT00218374

COMPLETED Phase 1

Ph1 Marinol Interaction Study - Part 2 - 1

NCT00490269

COMPLETED Phase 2

Evaluating Alternative Aftercare Models for Ex-offenders

NCT01586689

COMPLETED

The Neuropsychiatric Evaluation of HIV-Positive and Negative Drug Using Individuals: Study 215

NCT01034800

COMPLETED

Screening Protocol for the Evaluation of Potential Research Subjects

NCT01036971

COMPLETED

Screening Protocol for the Evaluation of Research Participants

NCT01036217

COMPLETED

Influence of Nicotine on Cognitive Function in Schizophrenic Patients With and Without Comorbid Drug Dependence

NCT01037075

COMPLETED Phase 1

Rivastigmine For Methamphetamine Dependent Individuals

NCT00158210

COMPLETED Phase 2

Efficacy of NicVAX in Smokers Who Want to Quit Smoking

NCT00318383

COMPLETED Phase 1

Antagonist-Elicited Cannabis Withdrawal

NCT01041170

COMPLETED

Study of Smoking Abstinence

NCT01035632

COMPLETED Phase 2

Topiramate for the Treatment of Methamphetamine Dependence - 1

NCT00345371

COMPLETED Phase 1

Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers

NCT01034020

COMPLETED

Neuroimaging Studies of Neurophysiological Phenotypes in Schizophrenia

NCT01036568

COMPLETED NA

Strategies to Help Adult ED Patients Quit Smoking

NCT00297466

COMPLETED Phase 1

Emergency Department Initiated Tobacco Treatment (EDITT)

NCT00252902

COMPLETED

Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms

NCT01603992

COMPLETED Phase 1

Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients

NCT00295308

COMPLETED Phase 2

Effectiveness of Bupropion Combined With Behavioral Therapy for Treating Methamphetamine Dependence - 2

NCT00135785

COMPLETED

Smoking and Alcohol Initiation

NCT00271843

COMPLETED

Effect of Functional Genetic Polymorphisms on Brain Morphology and Function

NCT01035723

COMPLETED

A Survey on Consumer Use of Over-the-Counter (OTC) Nicotine Patches

NCT00134927

COMPLETED

Assessing the Variability Over Time of Tobacco Carcinogen Biomarkers in Smokers - 2

NCT00158145

COMPLETED Phase 2

Effectiveness of Reducing Smoking in Facilitating Smoking Cessation in Adolescents - 2

NCT00158158

COMPLETED Phase 1

Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1

NCT00265265

COMPLETED Phase 4

Impact of Smoking Cessation on Sleep - 5

NCT00132821

COMPLETED Phase 1

Effect of Clonidine on Responses to Imagery Scripts

NCT00318760

COMPLETED Phase 3

Smoking Treatment of Prisoners

NCT00110630

COMPLETED NA

Metabolic Effects of Cocaine

NCT00451230

COMPLETED

Cognitive Task Development and Implementation for Functional MRI Studies

NCT01036685

COMPLETED Phase 3

Drug Use Prevention Among Girls Through a Mother-Daughter Intervention

NCT00310258

COMPLETED Phase 3

Effectiveness of Bupropion for Smokers Recovering From Alcohol Dependence

NCT00304707

COMPLETED Phase 2

Addition of Naltrexone to Methadone Taper

NCT00135759

COMPLETED

Reward Processing in Cocaine Addiction

NCT01036074

COMPLETED

Dopamine Function and Reward Processing In Schizophrenia

NCT01035996

COMPLETED Phase 2

Effectiveness of Selegiline in Treating Marijuana Dependent Individuals - 1

NCT00218517

COMPLETED Phase 2

Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine

NCT00777569

COMPLETED Phase 2

Effectiveness of Bupropion in Treating Marijuana Dependent Individuals

NCT00142870

COMPLETED

fMRI Study of Nicotinic Effect on Neurophysiology of Schizophrenia

NCT01046526

COMPLETED Phase 2

Tramadol to Reduce Opioid Withdrawal Symptoms

NCT00142896

COMPLETED Phase 2

Nicotine Lozenge to Reduce Smokeless Tobacco Use

NCT00218283

TERMINATED Phase 2

Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking

NCT00248118

TERMINATED

Methylphenidate Studies for Drug Abuse Vulnerability Molecular Genentics

NCT00247689

TERMINATED Phase 1

Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals

NCT00218049

COMPLETED Phase 2

Atomoxetine for the Treatment of Cannabis Dependence

NCT00167297

COMPLETED Phase 2

Modafinil for the Treatment of Cocaine Dependence - 1

NCT00100100

COMPLETED Phase 2

Baclofen for the Treatment of Cocaine Dependence - 1

NCT00082485

TERMINATED Phase 2

Abuse Potential of Buprenorphine/Naloxone

NCT00149539

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What the Pipeline for National Institute on Drug Abuse (NIDA) Shows

According to the ClinicalTrials.gov registry, National Institute on Drug Abuse (NIDA) is linked to 335 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 292 are already marked complete, representing roughly 87% of the total.

The phase mix for National Institute on Drug Abuse (NIDA) reports 30 late-stage studies (Phase 3 and Phase 4 combined) and 202 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute on Drug Abuse (NIDA) is Cocaine-Related Disorders with 17 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.