National Institute on Drug Abuse (NIDA)

335 total trials 14 currently recruiting 292 completed

National Institute on Drug Abuse (NIDA) sponsors 335 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 292 completed. 30 of these trials are in Phase 3-4 (later-stage) and 202 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cocaine-Related Disorders, with 17 trials.

Trial Pipeline

335 total, page 2 of 7

COMPLETED

Understanding Drug Abuse Treatment Outcomes

NCT01678833

COMPLETED

Health Outcomes by Neighborhood - Baltimore

NCT01571752

COMPLETED

Individual Differences in Reward and Impulse Control

NCT01621607

TERMINATED Early Phase 1

Pexacerfont for Stress-induced Food Craving

NCT01656577

COMPLETED

Stem Cell Study of Genetics and Drug Addiction

NCT01534624

TERMINATED Phase 1

Pioglitazone to Treat Opioid Withdrawal Symptoms

NCT01517165

COMPLETED Phase 1

Phase 1 Naltrexone-Bupropion-Methamphetamine Interaction Study

NCT01359930

COMPLETED

Brain Functions Underlying Visuospatial Attention Deficits in Schizophrenia

NCT01399437

COMPLETED

Brain Circuits in Schizophrenia and Smoking

NCT01369966

COMPLETED

Neutral Correlates of Risk-taking in Adolescents Exposed to Drugs Prenatally

NCT01365988

COMPLETED

Characterization of Phenotypic and Genotypic Regressors for Imaging

NCT01148381

COMPLETED

Nicotinic Modulation of the Default Network of Resting Brain Function

NCT01240616

COMPLETED Early Phase 1

Automated Prize-based Contingency Management to Increase Counseling Attendance in Opiate-Replacement-Therapy Patients

NCT01229163

COMPLETED

Effects of Antipsychotics on Eating and Food Craving in People With Schizophrenia

NCT01222793

COMPLETED

Assessment of Cannabis Craving in Schizophrenia Using Virtual Reality

NCT01212081

TERMINATED Phase 1

Interactions Between Intravenous (IV) Cocaine and Lofexidine

NCT01148992

COMPLETED

The Effects of Expectation on Natural and Drug -Induced Rewards

NCT01036230

COMPLETED

Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic Polymorphisms

NCT01505725

COMPLETED Phase 1

Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis

NCT01071616

COMPLETED Phase 1

Assessing Top Down and Bottom Up Attention Mechanisms in Smokers Using Nicotine Nasal Spray

NCT01136642

COMPLETED Phase 1

Phase 1 Study to Evaluate RDC-0313 Coadministered With Buprenorphine to Opioid-Experienced Healthy Adults

NCT01046539

COMPLETED

Measuring Distress Tolerance With Functional MRI

NCT01038232

COMPLETED

Prenatal Drug Exposure: Effects on the Adolescent Brain and Behavior Development

NCT01020669

COMPLETED

Risk Perception in Drug-Dependent Adults With and Without Schizophrenia

NCT01031563

COMPLETED

Assessment of Craving in Nicotine-Dependent Patients With Schizophrenia Using Virtual Reality

NCT01031433

COMPLETED

Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatient Treatment Population

NCT00787423

TERMINATED

Brain Glutamate Receptors and Cocaine Dependence

NCT00951314

COMPLETED Phase 1

Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction

NCT01031693

COMPLETED Phase 2

Reinforcement-Based Treatment for Pregnant Drug Abusers

NCT01177982

COMPLETED

Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From Nonsmokers

NCT01031121

COMPLETED

Effects of Nicotine on Areas of Impaired and Preserved Functioning in Schizophrenia

NCT01034085

COMPLETED

Screening Protocol for the Evaluation of Research Participants at the Maryland Psychiatric Research Center (MPRC)

NCT01030835

COMPLETED Phase 2

Effectiveness of Motivational Interviewing Supervision in Community Programs

NCT01586676

COMPLETED

A Multi-Modal Investigation of the Smoking Cessation Medication Varenicline: Dopaminergic Modulation of Reward Processing and Cognitive Control

NCT00830739

TERMINATED Phase 4

Oxytocin and Cognitive Behavioral Therapy in Drug Dependence

NCT00975416

COMPLETED Phase 1

Buprenorphine Naltrexone-P1 A-Cocaine

NCT00733720

COMPLETED

Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Adolescent Smokers

NCT01148355

COMPLETED Phase 1

Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients

NCT00780702

COMPLETED Phase 2

Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence

NCT00687713

COMPLETED Phase 1

Vigabatrin Ph 1 Cocaine Interaction Study

NCT00626834

COMPLETED Phase 1

Effects of Smoking on Opioid Receptor Binding: A PET Study

NCT00618631

TERMINATED Phase 1

Effects of Propranolol on Responses to Drug-Related Imagery Scripts

NCT00688805

COMPLETED Phase 2

Phase 2, Multi-Center Trial of Modafinil for Methamphetamine Dependence

NCT00520286

COMPLETED NA

Preventing Substance Use and Risky Behavior Among Rural African American Youth

NCT00535704

COMPLETED Phase 1

The Discriminative Effects of Tramadol in Humans

NCT00499746

COMPLETED

PET Imaging of Nicotinic Acetylcholine Receptors

NCT01046513

COMPLETED

Optimizing Toxicological Screening in Drug Endangered Children

NCT01037569

COMPLETED Phase 2

Selegiline for Smoking Cessation - 1

NCT00439413

COMPLETED Phase 1

Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, Physiology and Brain Activation

NCT01037608

COMPLETED

A Timeline Study of Alcohol Use and Its Relationship to Insomnia

NCT00580411

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What the Pipeline for National Institute on Drug Abuse (NIDA) Shows

According to the ClinicalTrials.gov registry, National Institute on Drug Abuse (NIDA) is linked to 335 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 292 are already marked complete, representing roughly 87% of the total.

The phase mix for National Institute on Drug Abuse (NIDA) reports 30 late-stage studies (Phase 3 and Phase 4 combined) and 202 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute on Drug Abuse (NIDA) is Cocaine-Related Disorders with 17 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.