National Institute on Drug Abuse (NIDA)
National Institute on Drug Abuse (NIDA) sponsors 335 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 292 completed. 30 of these trials are in Phase 3-4 (later-stage) and 202 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cocaine-Related Disorders, with 17 trials.
Trial Pipeline
335 total, page 2 of 7
Understanding Drug Abuse Treatment Outcomes
NCT01678833
Health Outcomes by Neighborhood - Baltimore
NCT01571752
Individual Differences in Reward and Impulse Control
NCT01621607
Pexacerfont for Stress-induced Food Craving
NCT01656577
Stem Cell Study of Genetics and Drug Addiction
NCT01534624
Pioglitazone to Treat Opioid Withdrawal Symptoms
NCT01517165
Phase 1 Naltrexone-Bupropion-Methamphetamine Interaction Study
NCT01359930
Brain Functions Underlying Visuospatial Attention Deficits in Schizophrenia
NCT01399437
Brain Circuits in Schizophrenia and Smoking
NCT01369966
Neutral Correlates of Risk-taking in Adolescents Exposed to Drugs Prenatally
NCT01365988
Characterization of Phenotypic and Genotypic Regressors for Imaging
NCT01148381
Nicotinic Modulation of the Default Network of Resting Brain Function
NCT01240616
Automated Prize-based Contingency Management to Increase Counseling Attendance in Opiate-Replacement-Therapy Patients
NCT01229163
Effects of Antipsychotics on Eating and Food Craving in People With Schizophrenia
NCT01222793
Assessment of Cannabis Craving in Schizophrenia Using Virtual Reality
NCT01212081
Interactions Between Intravenous (IV) Cocaine and Lofexidine
NCT01148992
The Effects of Expectation on Natural and Drug -Induced Rewards
NCT01036230
Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic Polymorphisms
NCT01505725
Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis
NCT01071616
Assessing Top Down and Bottom Up Attention Mechanisms in Smokers Using Nicotine Nasal Spray
NCT01136642
Phase 1 Study to Evaluate RDC-0313 Coadministered With Buprenorphine to Opioid-Experienced Healthy Adults
NCT01046539
Measuring Distress Tolerance With Functional MRI
NCT01038232
Prenatal Drug Exposure: Effects on the Adolescent Brain and Behavior Development
NCT01020669
Risk Perception in Drug-Dependent Adults With and Without Schizophrenia
NCT01031563
Assessment of Craving in Nicotine-Dependent Patients With Schizophrenia Using Virtual Reality
NCT01031433
Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatient Treatment Population
NCT00787423
Brain Glutamate Receptors and Cocaine Dependence
NCT00951314
Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction
NCT01031693
Reinforcement-Based Treatment for Pregnant Drug Abusers
NCT01177982
Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From Nonsmokers
NCT01031121
Effects of Nicotine on Areas of Impaired and Preserved Functioning in Schizophrenia
NCT01034085
Screening Protocol for the Evaluation of Research Participants at the Maryland Psychiatric Research Center (MPRC)
NCT01030835
Effectiveness of Motivational Interviewing Supervision in Community Programs
NCT01586676
A Multi-Modal Investigation of the Smoking Cessation Medication Varenicline: Dopaminergic Modulation of Reward Processing and Cognitive Control
NCT00830739
Oxytocin and Cognitive Behavioral Therapy in Drug Dependence
NCT00975416
Buprenorphine Naltrexone-P1 A-Cocaine
NCT00733720
Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Adolescent Smokers
NCT01148355
Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients
NCT00780702
Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence
NCT00687713
Vigabatrin Ph 1 Cocaine Interaction Study
NCT00626834
Effects of Smoking on Opioid Receptor Binding: A PET Study
NCT00618631
Effects of Propranolol on Responses to Drug-Related Imagery Scripts
NCT00688805
Phase 2, Multi-Center Trial of Modafinil for Methamphetamine Dependence
NCT00520286
Preventing Substance Use and Risky Behavior Among Rural African American Youth
NCT00535704
The Discriminative Effects of Tramadol in Humans
NCT00499746
PET Imaging of Nicotinic Acetylcholine Receptors
NCT01046513
Optimizing Toxicological Screening in Drug Endangered Children
NCT01037569
Selegiline for Smoking Cessation - 1
NCT00439413
Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, Physiology and Brain Activation
NCT01037608
A Timeline Study of Alcohol Use and Its Relationship to Insomnia
NCT00580411
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 81 |
| Phase 2 | 121 |
| Phase 3 | 14 |
| Phase 4 | 16 |
What the Pipeline for National Institute on Drug Abuse (NIDA) Shows
According to the ClinicalTrials.gov registry, National Institute on Drug Abuse (NIDA) is linked to 335 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 292 are already marked complete, representing roughly 87% of the total.
The phase mix for National Institute on Drug Abuse (NIDA) reports 30 late-stage studies (Phase 3 and Phase 4 combined) and 202 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute on Drug Abuse (NIDA) is Cocaine-Related Disorders with 17 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.