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Heroin Dependence clinical trials
All 12 indexed Heroin Dependence trials have closed enrollment.
12 US clinical trials ·
Heroin Dependence is the subject of 12 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 5 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute on Drug Abuse (NIDA), running 5 of these trials.
The research picture
Heroin Dependence has 12 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.
- 0
- recruiting participants now
- 0%
- of trials open to enrollment
- 5
- in Phase 3–4 (later-stage)
- 5
- top sponsor: National Institute on Drug Abuse (NIDA)
Active & Recent Trials
12 total, page 1 of 1
Buprenorphine/Naloxone Versus Clonidine for Outpatient Opiate Detoxification - 1
University of California, Los Angeles
NCT00032968
Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens
National Institute on Drug Abuse (NIDA)
NCT00218127
The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1
National Institute on Drug Abuse (NIDA)
NCT00158288
Directly Administered HIV Therapy in Methadone Clinics
Johns Hopkins University
NCT00279110
Behavioral Naltrexone Therapy for Promoting Adherence to Oral Naltrexone vs Extended Release Injectable Depot Naltrexone
New York State Psychiatric Institute
NCT00577408
Study of Computer-Based Treatment for Drug Dependence
Yale University
NCT01315184
Reinforcing Effects of Intranasal (IN) Buprenorphine Versus Buprenorphine/Naloxone
New York State Psychiatric Institute
NCT01760473
Opiate Dependence: Combined Naltrexone/Behavior Therapy - 1
New York State Psychiatric Institute
NCT00238914
A Laboratory Model for Heroin Abuse Medications - 8
New York State Psychiatric Institute
NCT00000273
Buprenorphine and Naloxone Combination Study - 10
National Institute on Drug Abuse (NIDA)
NCT00015288
Effects of Buspirone in Opiate Withdrawal
National Institute on Drug Abuse (NIDA)
NCT00326235
Study Comparing Liquid and Tablet Buprenorphine Formulations - 5
National Institute on Drug Abuse (NIDA)
NCT00000302
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 6 |
| Phase 3 | 4 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Heroin Dependence Trial Landscape
12 indexed Heroin Dependence studies · 0 recruiting (0%).
Phase mix: 5 late (III/IV) vs 7 early (I/II).
Top sponsor: National Institute on Drug Abuse (NIDA) (5 trials), 4 others listed. 12 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Heroin Dependence?
PlainTrial tracks 12 US clinical trials for Heroin Dependence, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Heroin Dependence?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.