National Institute on Drug Abuse (NIDA)
National Institute on Drug Abuse (NIDA) sponsors 335 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 292 completed. 30 of these trials are in Phase 3-4 (later-stage) and 202 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cocaine-Related Disorders, with 17 trials.
Trial Pipeline
335 total, page 4 of 7
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
NCT00129272
Examining the Effectiveness of the Nicotine Patch in Male and Female Smokers - 2
NCT00135746
Buprenorphine as a Treatment for Individuals Dependent on Analgesic Opioids
NCT00218101
A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder
NCT00593099
Neurobiology and Pharmacokinets of Acute MDMA Administration
NCT01148342
Treatment of Heroin and Cocaine With Methadone Maintenance and Contingency Management
NCT00292110
Behavioral Smoking Cessation Treatment - 1
NCT00110825
Preventing Depression in Methadone Maintenance Patients Receiving Hepatitis C Treatment - 1
NCT00218556
Contingency Management for Attendance - 2
NCT00249639
Effect of Bupropion on Smoking Behavior in Smokers With Schizophrenia
NCT00218231
An Hepatitis B Vaccine Model for HIV Vaccine Trials in Drug Users
NCT00841477
Opioid Agonist and Antagonist Effects on Opioid Dependence
NCT00142727
Positive Choice: Prevention for Positive Health
NCT00447707
Methylphenidate Raclopride Positron Emission Tomography (PET) Test - 11
NCT00015301
A Transtheoretical Model Group Therapy for Cocaine
NCT00178776
Nicotine and Cotinine Levels in Smokers With Schizophrenia and Schizoaffective Disorder - 2
NCT00135772
Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals
NCT00218309
Chronic Hepatitis Intervention Project for Drug Users
NCT00596843
Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Study
NCT00292136
Automatic Versus Evaluative Components of Cue Reactivity
NCT01036126
Vouchers vs. Prizes for Methadone Patients - 1
NCT00249522
Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smokers and in Heavy and Light Situational Smokers
NCT01038245
Bupropion for the Treatment of Methamphetamine Dependence - 1
NCT00069251
Modifying Group Therapy for Bipolar Substance Abusers - 1
NCT00227838
Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1
NCT00067535
Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1
NCT00249574
Treatment of Acute Hepatitis C Virus Infection With Pegylated Interferon in Injection Drug Users
NCT00194480
Naltrexone as Adjunct in Alcoholic Cocaine Dependent Patients - 4
NCT00000307
Effectiveness of N-acetylcysteine in Treating Cocaine Dependent Individuals - 1
NCT00136825
Effectiveness of Naltrexone and Lofexidine in Treating Detoxified Heroin Addicts - 1
NCT00218530
Effectiveness of Self-Help for Dually-Diagnosed Persons - 1
NCT00218582
Comparison of Buprenorphine and Methadone - 3
NCT00000334
Cocaethylene as a Treatment for Cocaine Dependence - 1
NCT00124696
Effectiveness of Using Tobacco Free Snuff in Reducing Negative Effects of Smokeless Tobacco Use
NCT00218270
Maintaining Abstinence in Chronic Cigarette Smokers - 1
NCT00087880
Physician Focused Intervention to Improve Adherence With HIV Antiretrovirals
NCT00870792
Tiagabine for the Treatment of Cocaine Dependence - 1
NCT00086255
Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI
NCT01036711
Effects of Buprenorphine/Naloxone in Treating Opioid Dependent Individuals Who Are Maintained on Methadone
NCT00000243
Effects of Nicotine on Brain Activity as Measured by fMRI
NCT01037153
Reinforcement-Based Treatment and Abstinence-Contingent Housing for Drug Abusers
NCT00685620
Clonidine as Adjunct Therapy for the Treatment of Neonatal Abstinence Syndrome
NCT00510016
Combination Pharmacotherapy for Smoking Cessation Among Methadone Patients
NCT00060814
Study to Reduce Intravenous Exposures (STRIVE)
NCT00391482
Ondansetron for the Treatment of Methamphetamine Dependence - 1
NCT00040053
Effects of Transdermal Nicotine on Smoking, Craving and Withdrawal in People With Schizophrenia
NCT00218218
Nicotine Replacement Treatment for Pregnant Smokers - 1
NCT00115687
Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1
NCT00158171
Effects of Buspirone in Opiate Withdrawal
NCT00326235
Incentive Programs for Female Substance Abusers Who Smoke - 3
NCT00064922
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 81 |
| Phase 2 | 121 |
| Phase 3 | 14 |
| Phase 4 | 16 |
What the Pipeline for National Institute on Drug Abuse (NIDA) Shows
According to the ClinicalTrials.gov registry, National Institute on Drug Abuse (NIDA) is linked to 335 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 292 are already marked complete, representing roughly 87% of the total.
The phase mix for National Institute on Drug Abuse (NIDA) reports 30 late-stage studies (Phase 3 and Phase 4 combined) and 202 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute on Drug Abuse (NIDA) is Cocaine-Related Disorders with 17 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.