National Institutes of Health Clinical Center (CC)

209 total trials 135 currently recruiting 67 completed

Trial Pipeline

RECRUITING

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

NCT06998134

RECRUITING NA

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

NCT05473429

RECRUITING

Blood Sampling Pre- and Post-Propofol Administration to Characterize the Blood Proteome Using Different Research Assays

NCT07295795

RECRUITING

Metagenomics Next-generation Sequencing Approach to Detect Microbial DNA/RNA Overtime in Individuals Undergoing Hematopoietic Stem Cell Transplant

NCT06904053

RECRUITING Phase 1

Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain

NCT05695339

RECRUITING

A Natural History Study of RYR1-Related Disorders

NCT06287762

RECRUITING

Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.

NCT06498596

RECRUITING

The Impact of Heavy Alcohol Use on Saliva and Oral Health

NCT06684483

RECRUITING NA

A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

NCT05909202

RECRUITING NA

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

NCT05726591

RECRUITING

Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease

NCT05170412

RECRUITING NA

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

NCT04305431

RECRUITING

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

NCT03253705

RECRUITING Phase 2

Spironolactone for Pulmonary Arterial Hypertension

NCT01712620

RECRUITING

Cerebral Palsy and the Study of Brain Activity During Motor Tasks

NCT01829724

RECRUITING

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

NCT01730092

RECRUITING Phase 4

Improving White Blood Cell Collection From Healthy Donors

NCT01553214

RECRUITING

Imaging Techniques in MRI

NCT01130545

RECRUITING

Study of Lung Proteins in Patients With Pneumonia

NCT00077909

RECRUITING

MRI Study of Musculoskeletal Function

NCT00051857

RECRUITING

Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use

NCT00001846

RECRUITING

Human Movement Database

NCT00001252

ACTIVE NOT RECRUITING

Cefiderocol vs Best Available Therapy for Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex Infections: A Target Trial Emulation

NCT07226557

ACTIVE NOT RECRUITING

Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals

NCT06651645

ACTIVE NOT RECRUITING Phase 1

COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE)

NCT04595773

ACTIVE NOT RECRUITING

Evaluation of Atherosclerotic Plaques in Abdominal CT Studies

NCT04652973

ACTIVE NOT RECRUITING

Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Existing Radiologic Images

NCT04579237

ACTIVE NOT RECRUITING

Assisted Suicide in Switzerland

NCT04261088

ACTIVE NOT RECRUITING Phase 2

Treatment of Hemochromatosis

NCT00007150

COMPLETED

Saliva as Source of Detection for SARS-CoV-2

NCT04424446

COMPLETED

Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research

NCT03709303

COMPLETED

Characteristics and Outcomes of a Capacity-to-Consent Assessment Service

NCT03258606

COMPLETED Phase 1

Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted With Cobicistat in Healthy Volunteers

NCT02771249

COMPLETED Phase 2

Integrated Imaging Strategy to Phenotype Progression of Liver Tumors During and After Chemoembolization

NCT02471313

COMPLETED Phase 2

Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

NCT02257853

COMPLETED

Web-based Patient Reported Outcome Measurement Information System (PROMIS ) to Explore Burden and Stress in Cancer Caregivers (BaSiC2)

NCT01981538

COMPLETED NA

Study of New Software Used During Ablations

NCT01906021

COMPLETED

Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain

NCT01862731

COMPLETED Phase 2

Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia

NCT01859312

COMPLETED

Estimating Brain Biomechanics Using MRI

NCT01633268

COMPLETED NA

Yoga as Self-Care for Arthritis in Minority Communities

NCT01617421

COMPLETED

Studying Childhood-Onset Hemidystonia

NCT01432899

COMPLETED

Long-Term Study of Liver Disease in People With Hepatitis B and/or Hepatitis C With or Without HIV Infection

NCT01350648

COMPLETED

Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection

NCT01150721

COMPLETED

Noninvasive Imaging of Heart Failure: A Pilot Study

NCT01160471

COMPLETED

X-Ray Mammography Standard of Care Protocol

NCT01052740

COMPLETED Phase 2

Problem-Solving Education for Caregivers and Patients During Stem Cell Transplant

NCT00766883

COMPLETED Phase 1

Positron Emission Tomography Using [18F]-Labeled Substance P Antagonist Receptor Quantifier in Finding Disease in Patients With Pancreatic Cancer

NCT00547612

COMPLETED

Molecular Changes and Biomarkers in Chronic Myeloproliferative Disorders

NCT00433862

COMPLETED Phase 1

Education Program to Manage Emotional Stress of Stem Cell Transplant Recipients and Their Caregivers

NCT00423774

COMPLETED

Development of Serologic Assays for Human Herpes Virus-8

NCT00395278

COMPLETED Phase 1

ABT-888 in Patients With Refractory Solid Tumors or Hematologic Cancer

NCT00387608

COMPLETED

Iron Replacement in Blood Donors

NCT00327067

COMPLETED

Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields

NCT00340054

COMPLETED

Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma

NCT00226304

COMPLETED

Heart Disease in Sickle Cell Anemia

NCT00113152

COMPLETED Phase 4

Drug Interactions of Echinacea, Ginseng, and Ginkgo Biloba Taken With Lopinavir/Ritonavir in Healthy Volunteers

NCT00103012

COMPLETED

Views of Cancer Patients Regarding Financial Conflicts of Interest

NCT00097682

COMPLETED Phase 1

Carbon Monoxide to Prevent Lung Inflammation

NCT00094406

COMPLETED

The Effect of Sildenafil Citrate (Viagra® (Registered Trademark)) on Brain Blood Flow in Multiple Sclerosis Patients

NCT00094068

COMPLETED Phase 1

Heat Activated Liposomal Doxorubicin and Radiofrequency Ablation in Treating Patients With Primary or Metastatic Liver Tumors

NCT00093444

COMPLETED Phase 3

Oral Care to Reduce Mouth and Throat Infections in Critically Ill Patients

NCT00078663

COMPLETED Phase 2

Monoclonal Antibody With or Without gp100 Peptides Plus Montanide ISA-51 in Treating Patients With Stage IV Melanoma

NCT00077532

COMPLETED NA

Sentinel Lymph Node Biopsy and Primary Tumor Gene Expression Profiling in Finding Axillary Lymph Node Metastases in Women Who Have Received Neoadjuvant Therapy for Stage II, Stage III, or Stage IV Breast Cancer

NCT00080860

COMPLETED

Clinical Evaluations and Laboratory Studies to Study the Disease Course in Patients With Cutaneous T-Cell Lymphoma

NCT00430053

COMPLETED Phase 1

Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease

NCT00072826

COMPLETED

MR Perfusion Imaging and Hypercapnia (Increased Carbon Dioxide) to Study New Blood Vessel Formation in Multiple Sclerosis

NCT00064909

COMPLETED Phase 1

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

NCT00064311

COMPLETED

Development of Computer-aided Detection and Diagnosis From Imaging Techniques

NCT00057252

COMPLETED Phase 2

Daclizumab to Treat Chronic Immune Thrombocytopenia

NCT00049725

COMPLETED

Ethical Dilemmas in Clinical Practice: A Survey of European Physicians

NCT00352573

COMPLETED Phase 1

Monoclonal Antibody Therapy in Treating Patients With Lymphoma or Colon Cancer That Has Not Responded to Vaccine Therapy

NCT00047164

COMPLETED Phase 1

Endothelial Dysfunction as a Risk Factor in HIV Study

NCT00039663

COMPLETED Phase 4

Valganciclovir to Prevent Cytomegalovirus Infection in Kidney and Kidney/Pancreas Transplant Recipients

NCT00034385

COMPLETED

Study of Transfusion-Transmitted Infections

NCT00023023

COMPLETED Phase 1

Tipifarnib in Treating Young Patients With Refractory Leukemia

NCT00022451

COMPLETED

Study of Tongue Pressures

NCT00013832

COMPLETED Phase 3

Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver

NCT00020501

COMPLETED Phase 1

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

NCT00020579

COMPLETED Phase 1

The Effect of Milk Thistle on the Pharmacokinetics of Indinavir

NCT00011635

COMPLETED

Platelet Function in Patients Treated With SSRI and Non-SSRI Antidepressants

NCT00009568

COMPLETED

Structure and Function of the Human Tongue

NCT00007137

COMPLETED

Magnetic Resonance Imaging for Evaluating Kidney Function

NCT00006173

COMPLETED

Study of Brain Blood Flow During Induced Hypercapnia (Excess Blood Carbon Dioxide)

NCT00001845

COMPLETED Phase 2

Monoclonal Antibody Plus Chemotherapy in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2

NCT00019812

COMPLETED

Magnetic Resonance Angiography (MRA) for the Diagnosis of Atherosclerosis

NCT00001841

COMPLETED

Evaluation of Treated and Untreated Stroke

NCT00001840

COMPLETED Phase 2

A Randomized Trial of Antithymocyte Globulin Versus Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome

NCT00001839

COMPLETED

Detection of Coronary Artery Calcification: Comparison of Volumetric and Electron Beam Computed Tomography

NCT00001836

COMPLETED

Evaluation of Patients With Blood Disorders

NCT00001715

COMPLETED Phase 2

Leucovorin for the Treatment of 5 q Minus Syndrome

NCT00004997

COMPLETED

Comparison of Asymptomatic Carotid Atherosclerosis Between Frequent and Infrequent Blood Donors

NCT00001589

COMPLETED Phase 4

The Early Reversibility of Rocuronium After Different Doses of Neostigmine

NCT00001520

COMPLETED

Screening Study for the Department of Rehabilitation Medicine

NCT00023088

COMPLETED

Ultrasound and Videofluoroscopy for Diagnosing Swallowing Disorders

NCT00001220

COMPLETED

Ultrasound Evaluation of Tongue Movements in Speech and Swallowing

NCT00001167

Phase Distribution

PhaseTrial count
Phase 1 43
Phase 2 11
Phase 3 2
Phase 4 4

What the Pipeline for National Institutes of Health Clinical Center (CC) Shows

According to the ClinicalTrials.gov registry, National Institutes of Health Clinical Center (CC) is linked to 209 US clinical trials across every stage of research activity. Of those, 135 studies are currently recruiting — about 65% of the sponsor's indexed portfolio — and 67 are already marked complete, representing roughly 32% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for National Institutes of Health Clinical Center (CC) reports 6 late-stage studies (Phase 3 and Phase 4 combined) and 54 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for National Institutes of Health Clinical Center (CC) is Healthy with 8 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial