National Institutes of Health Clinical Center (CC)
Trial Pipeline
Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults
NCT06998134
Characterization of Nociception Phenotype in Individuals With Intellectual Disability
NCT05473429
Blood Sampling Pre- and Post-Propofol Administration to Characterize the Blood Proteome Using Different Research Assays
NCT07295795
Metagenomics Next-generation Sequencing Approach to Detect Microbial DNA/RNA Overtime in Individuals Undergoing Hematopoietic Stem Cell Transplant
NCT06904053
Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain
NCT05695339
A Natural History Study of RYR1-Related Disorders
NCT06287762
Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.
NCT06498596
The Impact of Heavy Alcohol Use on Saliva and Oral Health
NCT06684483
A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients
NCT05909202
Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders
NCT05726591
Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease
NCT05170412
Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease
NCT04305431
Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research
NCT03253705
Spironolactone for Pulmonary Arterial Hypertension
NCT01712620
Cerebral Palsy and the Study of Brain Activity During Motor Tasks
NCT01829724
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
NCT01730092
Improving White Blood Cell Collection From Healthy Donors
NCT01553214
Imaging Techniques in MRI
NCT01130545
Study of Lung Proteins in Patients With Pneumonia
NCT00077909
MRI Study of Musculoskeletal Function
NCT00051857
Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use
NCT00001846
Human Movement Database
NCT00001252
Cefiderocol vs Best Available Therapy for Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex Infections: A Target Trial Emulation
NCT07226557
Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals
NCT06651645
COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE)
NCT04595773
Evaluation of Atherosclerotic Plaques in Abdominal CT Studies
NCT04652973
Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Existing Radiologic Images
NCT04579237
Assisted Suicide in Switzerland
NCT04261088
Treatment of Hemochromatosis
NCT00007150
Saliva as Source of Detection for SARS-CoV-2
NCT04424446
Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research
NCT03709303
Characteristics and Outcomes of a Capacity-to-Consent Assessment Service
NCT03258606
Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted With Cobicistat in Healthy Volunteers
NCT02771249
Integrated Imaging Strategy to Phenotype Progression of Liver Tumors During and After Chemoembolization
NCT02471313
Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients
NCT02257853
Web-based Patient Reported Outcome Measurement Information System (PROMIS ) to Explore Burden and Stress in Cancer Caregivers (BaSiC2)
NCT01981538
Study of New Software Used During Ablations
NCT01906021
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
NCT01862731
Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia
NCT01859312
Estimating Brain Biomechanics Using MRI
NCT01633268
Yoga as Self-Care for Arthritis in Minority Communities
NCT01617421
Studying Childhood-Onset Hemidystonia
NCT01432899
Long-Term Study of Liver Disease in People With Hepatitis B and/or Hepatitis C With or Without HIV Infection
NCT01350648
Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection
NCT01150721
Noninvasive Imaging of Heart Failure: A Pilot Study
NCT01160471
X-Ray Mammography Standard of Care Protocol
NCT01052740
Problem-Solving Education for Caregivers and Patients During Stem Cell Transplant
NCT00766883
Positron Emission Tomography Using [18F]-Labeled Substance P Antagonist Receptor Quantifier in Finding Disease in Patients With Pancreatic Cancer
NCT00547612
Molecular Changes and Biomarkers in Chronic Myeloproliferative Disorders
NCT00433862
Education Program to Manage Emotional Stress of Stem Cell Transplant Recipients and Their Caregivers
NCT00423774
Development of Serologic Assays for Human Herpes Virus-8
NCT00395278
ABT-888 in Patients With Refractory Solid Tumors or Hematologic Cancer
NCT00387608
Iron Replacement in Blood Donors
NCT00327067
Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields
NCT00340054
Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma
NCT00226304
Heart Disease in Sickle Cell Anemia
NCT00113152
Drug Interactions of Echinacea, Ginseng, and Ginkgo Biloba Taken With Lopinavir/Ritonavir in Healthy Volunteers
NCT00103012
Views of Cancer Patients Regarding Financial Conflicts of Interest
NCT00097682
Carbon Monoxide to Prevent Lung Inflammation
NCT00094406
The Effect of Sildenafil Citrate (Viagra® (Registered Trademark)) on Brain Blood Flow in Multiple Sclerosis Patients
NCT00094068
Heat Activated Liposomal Doxorubicin and Radiofrequency Ablation in Treating Patients With Primary or Metastatic Liver Tumors
NCT00093444
Oral Care to Reduce Mouth and Throat Infections in Critically Ill Patients
NCT00078663
Monoclonal Antibody With or Without gp100 Peptides Plus Montanide ISA-51 in Treating Patients With Stage IV Melanoma
NCT00077532
Sentinel Lymph Node Biopsy and Primary Tumor Gene Expression Profiling in Finding Axillary Lymph Node Metastases in Women Who Have Received Neoadjuvant Therapy for Stage II, Stage III, or Stage IV Breast Cancer
NCT00080860
Clinical Evaluations and Laboratory Studies to Study the Disease Course in Patients With Cutaneous T-Cell Lymphoma
NCT00430053
Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease
NCT00072826
MR Perfusion Imaging and Hypercapnia (Increased Carbon Dioxide) to Study New Blood Vessel Formation in Multiple Sclerosis
NCT00064909
Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation
NCT00064311
Development of Computer-aided Detection and Diagnosis From Imaging Techniques
NCT00057252
Daclizumab to Treat Chronic Immune Thrombocytopenia
NCT00049725
Ethical Dilemmas in Clinical Practice: A Survey of European Physicians
NCT00352573
Monoclonal Antibody Therapy in Treating Patients With Lymphoma or Colon Cancer That Has Not Responded to Vaccine Therapy
NCT00047164
Endothelial Dysfunction as a Risk Factor in HIV Study
NCT00039663
Valganciclovir to Prevent Cytomegalovirus Infection in Kidney and Kidney/Pancreas Transplant Recipients
NCT00034385
Study of Transfusion-Transmitted Infections
NCT00023023
Tipifarnib in Treating Young Patients With Refractory Leukemia
NCT00022451
Study of Tongue Pressures
NCT00013832
Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver
NCT00020501
MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma
NCT00020579
The Effect of Milk Thistle on the Pharmacokinetics of Indinavir
NCT00011635
Platelet Function in Patients Treated With SSRI and Non-SSRI Antidepressants
NCT00009568
Structure and Function of the Human Tongue
NCT00007137
Magnetic Resonance Imaging for Evaluating Kidney Function
NCT00006173
Study of Brain Blood Flow During Induced Hypercapnia (Excess Blood Carbon Dioxide)
NCT00001845
Monoclonal Antibody Plus Chemotherapy in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2
NCT00019812
Magnetic Resonance Angiography (MRA) for the Diagnosis of Atherosclerosis
NCT00001841
Evaluation of Treated and Untreated Stroke
NCT00001840
A Randomized Trial of Antithymocyte Globulin Versus Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome
NCT00001839
Detection of Coronary Artery Calcification: Comparison of Volumetric and Electron Beam Computed Tomography
NCT00001836
Evaluation of Patients With Blood Disorders
NCT00001715
Leucovorin for the Treatment of 5 q Minus Syndrome
NCT00004997
Comparison of Asymptomatic Carotid Atherosclerosis Between Frequent and Infrequent Blood Donors
NCT00001589
The Early Reversibility of Rocuronium After Different Doses of Neostigmine
NCT00001520
Screening Study for the Department of Rehabilitation Medicine
NCT00023088
Ultrasound and Videofluoroscopy for Diagnosing Swallowing Disorders
NCT00001220
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing
NCT00001167
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 43 |
| Phase 2 | 11 |
| Phase 3 | 2 |
| Phase 4 | 4 |
Therapeutic Areas
What the Pipeline for National Institutes of Health Clinical Center (CC) Shows
According to the ClinicalTrials.gov registry, National Institutes of Health Clinical Center (CC) is linked to 209 US clinical trials across every stage of research activity. Of those, 135 studies are currently recruiting — about 65% of the sponsor's indexed portfolio — and 67 are already marked complete, representing roughly 32% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for National Institutes of Health Clinical Center (CC) reports 6 late-stage studies (Phase 3 and Phase 4 combined) and 54 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for National Institutes of Health Clinical Center (CC) is Healthy with 8 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.