National Institutes of Health Clinical Center (CC)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institutes of Health Clinical Center (CC) sits in the top decile of US sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count).

338 total trials 22 currently recruiting 272 completed early-phase tilt top decile by trial count

National Institutes of Health Clinical Center (CC): 338 sponsored US clinical trials, 22 recruiting.

National Institutes of Health Clinical Center (CC) sponsors 338 registered US clinical trials on ClinicalTrials.gov, 22 of them currently recruiting, and 272 completed. 17 of these trials are in Phase 3-4 (later-stage) and 121 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 8 trials.

Top-decile sponsor footprint

National Institutes of Health Clinical Center (CC) ranks in the top decile of sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

272 of 308 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

338 total, page 1 of 7

RECRUITING

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

NCT06998134

RECRUITING NA

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

NCT05473429

RECRUITING

Blood Sampling Pre- and Post-Propofol Administration to Characterize the Blood Proteome Using Different Research Assays

NCT07295795

RECRUITING

Metagenomics Next-generation Sequencing Approach to Detect Microbial DNA/RNA Overtime in Individuals Undergoing Hematopoietic Stem Cell Transplant

NCT06904053

RECRUITING Phase 1

Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain

NCT05695339

RECRUITING

A Natural History Study of RYR1-Related Disorders

NCT06287762

RECRUITING

Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.

NCT06498596

RECRUITING

The Impact of Heavy Alcohol Use on Saliva and Oral Health

NCT06684483

RECRUITING NA

A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

NCT05909202

RECRUITING NA

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

NCT05726591

RECRUITING

Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease

NCT05170412

RECRUITING NA

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

NCT04305431

RECRUITING

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

NCT03253705

RECRUITING Phase 2

Spironolactone for Pulmonary Arterial Hypertension

NCT01712620

RECRUITING

Cerebral Palsy and the Study of Brain Activity During Motor Tasks

NCT01829724

RECRUITING

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

NCT01730092

RECRUITING Phase 4

Improving White Blood Cell Collection From Healthy Donors

NCT01553214

RECRUITING

Imaging Techniques in MRI

NCT01130545

RECRUITING

Study of Lung Proteins in Patients With Pneumonia

NCT00077909

RECRUITING

MRI Study of Musculoskeletal Function

NCT00051857

RECRUITING

Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use

NCT00001846

RECRUITING

Human Movement Database

NCT00001252

ACTIVE NOT RECRUITING

Cefiderocol vs Best Available Therapy for Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex Infections: A Target Trial Emulation

NCT07226557

ACTIVE NOT RECRUITING

Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals

NCT06651645

ACTIVE NOT RECRUITING Phase 1

COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE)

NCT04595773

ACTIVE NOT RECRUITING

Evaluation of Atherosclerotic Plaques in Abdominal CT Studies

NCT04652973

ACTIVE NOT RECRUITING

Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Existing Radiologic Images

NCT04579237

ACTIVE NOT RECRUITING

Assisted Suicide in Switzerland

NCT04261088

ACTIVE NOT RECRUITING Phase 2

Treatment of Hemochromatosis

NCT00007150

NOT YET RECRUITING

Pulmonary Hypertension (PH) Biorepository for Translational Research

NCT07647549

COMPLETED NA

Feasibility of Measuring Volume of Inspiration Via Noninvasive Motion Sensors

NCT06609616

COMPLETED

Adolescents Seeking COVID Vaccination (Teen COVID Vax)

NCT05537103

COMPLETED NA

Mediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy Adults

NCT05411120

TERMINATED NA

Electromagnetic Tracking and Optical Imaging With ICG for Hepatic Biopsies

NCT04258566

COMPLETED NA

The Effect of a Combined Nature-based and Virtual Mindfulness Intervention on Perceived Stress in Healthcare Workers

NCT04846790

COMPLETED

Hospital COVID-19 Surge and Associated Mortality Risk

NCT04688372

COMPLETED

Trimethoprim-Sulfamethoxazole vs Levofloxacin as Targeted Therapy for Stenotrophomonas Maltophilia Infections: a Retrospective Cohort Study

NCT04639817

COMPLETED

Saliva as Source of Detection for SARS-CoV-2

NCT04424446

COMPLETED

Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons

NCT04401449

COMPLETED

Plasma Collection From Convalescent and/or Immunized Donors for the Treatment of COVID-19

NCT04360278

COMPLETED

Collecting Interval Timed Incisional Epidermal and Dermal Tissue Samples During Surgical Procedures to Profile Temporal Response of Tissue After Noxious Stimuli

NCT04224870

COMPLETED NA

Translational Development of Photon-counting CT Imaging

NCT03878134

COMPLETED Early Phase 1

A Dose-Finding Study of AG-348 in Sickle Cell Disease

NCT04000165

TERMINATED Phase 2

The SOLID Platelet Study

NCT03712618

COMPLETED Phase 1

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

NCT03864406

TERMINATED

Characterizing Fatigue Experienced by Registered Nurses

NCT03789188

COMPLETED NA

RCT of Web-Based Behavioral Sleep Intervention for Individuals With Alcohol Use Disorder

NCT03493958

COMPLETED Phase 1

The Influence of ANS-6637 on Midazolam Pharmacokinetics in Healthy Volunteers

NCT03831971

COMPLETED

Focus Groups to Determine Surrogates Views Regarding Patient Preference Predictors

NCT02898194

COMPLETED Phase 1

PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects

NCT03581305

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Phase Distribution

PhaseTrial count
Phase 1 74
Phase 2 47
Phase 3 6
Phase 4 11

What is open in the National Institutes of Health Clinical Center (CC) pipeline

22 recruiting of 338 indexed (7% open); 272 completed (80%).

Phase mix: 17 late (III/IV) vs 121 early (I/II) (early-phase heavy).

Top condition: Healthy (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institutes of Health Clinical Center (CC): open-pipeline peers nationwide

Peers matched on 338 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 0%5%10%15%20%25% Total trials Recruiting share National Institutes of Health Clinical Center (CC)Cedars-Sinai Medical CenterOhio State University Comprehensive Cancer CenterNational Institute on Drug Abuse (NIDA)Children's Oncology GroupAlliance for Clinical Trials in OncologyNICHD Neonatal Research NetworkInsmed IncorporatedBaylor Breast Care Center
National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 338 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this National Institutes of Health Clinical Center (CC) page

338 registered trials is a research-attention snapshot, not an endorsement of National Institutes of Health Clinical Center (CC) or any single study.

  • 22 of National Institutes of Health Clinical Center (CC)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition National Institutes of Health Clinical Center (CC) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institutes of Health Clinical Center (CC) pipeline card: 338 registered trials from official public datasets.Report a data error.