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NCT01048957 · ClinicalTrials.gov registry record · NA
The Neural Basis of Cue-Elicited Cigarette Craving and Its Control
A NA study, sponsored by National Institute on Drug Abuse (NIDA).
- Completed
- Registry status
- NA
- Development phase
- 79
- Enrollment target
NCT01048957 is a NA study that has completed, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 79 participants.
The verdict
NCT01048957, a NA study, has completed, sponsored by National Institute on Drug Abuse (NIDA).
- COMPLETED
- Registry status
- NA
- Development phase
- 79 participants
- Enrollment target
Study Summary
Background: \- One kind of drug craving, known as cue-elicited craving, occurs when a drug user who sees a drug-related cue (such as an image of someone using the drug) begins to feel a craving for the drug. Researchers are interested in studying how cue-elicited craving affects brain activity using functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) data. Objectives: \- To determine which parts of the brain are associated with or involved in controlling cue-related craving in smokers. Eligibility: \- Individuals between 18 and 50 years of age who are current smokers (10 or more cigarettes per day) and agree to try to abstain from smoking for 1 week during the experiment. Design: * Participants will visit a clinical center for up to four scanning sessions, and will be asked to perform two or three outpatient tasks at home over the course of the study. * Scan 1: Training session with a mock fMRI scanner, followed by an actual fMRI scanning session and EEG in which participants respond to pictures. * Outpatient Task 1: Tolerance test with nicotine patch (worn for 8 hours, followed by 12 additional hours without cigarette use). * Scans 2 and 3: Training session and fMRI scan and testing with either nicotine patch or placebo. Tasks in fMRI involve looking at cues, reporting craving and suppressing craving. * Outpatient Task 2: Participants will keep an electronic diary for 10 to 14 days, responding to questions as directed by the researchers. * Scans 4 and 5: Training session, fMRI scan and EEG, and testing in which participants will be instructed on methods to attempt to control cravings. * Outpatient Task 3: Participants will keep an electronic diary for 14 days. For the first 7 days, participants will be asked to attempt to abstain from nicotine; participants may smoke normally on the second 7 days. * Participants will be contacted 1, 3, 6, and 12 months after the end of the study for follow-up questions on current smoking habits.
Interventions
- BEHAVIORAL Real Time Feedback Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 79 participants |
| Start Date | 2007-01-09 |
| Est. Completion | 2013-04-08 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01048957
The ClinicalTrials.gov registry entry for NCT01048957 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 79 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute on Drug Abuse (NIDA), which has 335 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Real Time Feedback Training is the first listed.
NCT01048957 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01048957 about?
NCT01048957 is a clinical study titled "The Neural Basis of Cue-Elicited Cigarette Craving and Its Control". Background: \- One kind of drug craving, known as cue-elicited craving, occurs when a drug user who sees a drug-related cue (such as an image of someone using the drug) begins to feel a craving for the drug. Researchers are interested in studying how cue-elicited craving affects brain activity usin...
What is the current status of trial NCT01048957?
This trial is currently completed. It is a NA study. The enrollment target is 79 participants. The study started on 2007-01-09. Estimated completion is 2013-04-08.
What interventions are being tested in trial NCT01048957?
The interventions under investigation include: Real Time Feedback Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT01048957?
This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.
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