Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00438139 · ClinicalTrials.gov registry record · Phase 1

Ph1 Marinol Interaction Study - Part 1 - 1

A Phase 1 study, sponsored by National Institute on Drug Abuse (NIDA).

Terminated
Registry status
Phase 1
Development phase
6
Enrollment target

NCT00438139: Clinical Trial Phase 1 study, sponsored by National Institute on Drug Abuse (NIDA).

NCT00438139 is a Phase 1 study that was terminated before completion, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00438139, a Phase 1 study, was terminated before completion, sponsored by National Institute on Drug Abuse (NIDA).

TERMINATED
Registry status
Phase 1
Development phase
6 participants
Enrollment target

Study Summary

The purpose of this study is to examine the effects of oral dronabinol tetrahydrocannabinol (THC) on withdrawal symptoms in marijuana dependent volunteers, and evaluate the safety, pharmacokinetics (PK), and cardiovascular effects of the combination of oral dronabinol and smoked marijuana to determine if there are potential significant interactions before conducting outpatient studies.

Interventions

  • DRUG Dronabinol

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2007-03
Est. Completion 2007-03
Phase Phase 1

Why NCT00438139 stopped before completion

NCT00438139 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which Dronabinol is the first listed.

NCT00438139 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00438139 about?

NCT00438139 is a clinical study titled "Ph1 Marinol Interaction Study - Part 1 - 1". The purpose of this study is to examine the effects of oral dronabinol tetrahydrocannabinol (THC) on withdrawal symptoms in marijuana dependent volunteers, and evaluate the safety, pharmacokinetics (PK), and cardiovascular effects of the combination of oral dronabinol and smoked marijuana to determi...

What is the current status of trial NCT00438139?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2007-03. Estimated completion is 2007-03.

What interventions are being tested in trial NCT00438139?

The interventions under investigation include: Dronabinol (DRUG).

Who is sponsoring clinical trial NCT00438139?

This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00438139's enrollment target sits among peer trials

6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00438139, the US trial registry maintained by the National Library of Medicine. NCT00438139 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.