Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cocaine-Related Disorders: early-phase trial registry
All 28 indexed Cocaine-Related Disorders trials have closed enrollment; the archived set skews early-phase.
Corpus placement: #577 of 28,707 conditions by registered trial count.
28 US clinical trials · none currently recruiting · #577 of 28,707 conditions by registered trial count
Cocaine-Related Disorders: 28 US clinical trials tracked, none currently recruiting.
Cocaine-Related Disorders is the subject of 28 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 4 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute on Drug Abuse (NIDA), running 17 of these trials.
Enrollment posture brief
Registry condition cocaine-related-disorders
OPEN 0 | RECR 0% | LATE 4 | EARLY 21 | RANK #577 | SPON 17
Volume-matched condition peers
Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)
Cocaine-Related Disorders has no open enrollment in this registry pull (28 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cocaine-Related Disorders on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cocaine-Related Disorders is recruiting below its size-band peers.
0 of 28 indexed trials (0%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Cocaine-Related Disorders research.
National Institute on Drug Abuse (NIDA) accounts for 17 of 28 trials (60.7%). 9 distinct sponsors appear on at least one study for this condition label.
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Most Cocaine-Related Disorders trials plan to enrol fewer than 100 people.
Median target enrolment is 41 among the 16 trials that report a genuine target (sentinel values excluded). 12 of those (75%) plan for fewer than 100 participants.
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Cocaine-Related Disorders research is mostly interventional.
27 interventional and 1 observational studies make up this index (96.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Indexed trials (enrollment closed)
28 total, page 1 of 1
Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1
University of Pennsylvania
NCT00142844
Venlafaxine to Reduce Cocaine Dependence in Depressed Individuals
New York State Psychiatric Institute
NCT00249483
Treatment of Heroin and Cocaine With Methadone Maintenance and Contingency Management
National Institute on Drug Abuse (NIDA)
NCT00292110
Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention
The University of Texas Health Science Center, Houston
NCT02896712
Progesterone for the Treatment of Cocaine Dependence - 1
University of Minnesota
NCT00218257
Ondansetron for the Treatment of Cocaine Dependence - 1
National Institute on Drug Abuse (NIDA)
NCT00033085
Quetiapine for Cocaine Use and Cravings
Seattle Institute for Biomedical and Clinical Research
NCT00232336
Gepirone vs Placebo in Treatment of Cocaine Dependence - 3
University of Pennsylvania
NCT00000189
Cocaine Abuse and Attention Deficit Disorder - 3
National Institute on Drug Abuse (NIDA)
NCT00000268
Atomoxetine for Treating Cocaine Abuse in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
New York State Psychiatric Institute
NCT00218543
Effectiveness of N-acetylcysteine in Treating Cocaine Dependent Individuals - 1
National Institute on Drug Abuse (NIDA)
NCT00136825
Cocaine Abuse and ADHD - 10
National Institute on Drug Abuse (NIDA)
NCT00000275
Therapeutic Potential of Kappa-Opioids Against Cocaine - 1
National Institute on Drug Abuse (NIDA)
NCT00000323
Open Label Pharmaco- Magnetic Resonance Spectrography (MRS) Study of Clavulanic Acid
Temple University
NCT03986762
Cocaethylene as a Treatment for Cocaine Dependence - 1
National Institute on Drug Abuse (NIDA)
NCT00124696
Cocaine-Methylphendidate Interaction Study - 4
National Institute on Drug Abuse (NIDA)
NCT00015067
Modeling Impaired Judgement in Cocaine Abusers - 6
National Institute on Drug Abuse (NIDA)
NCT00015236
Dose Response Trial of Pergolide for Cocaine Dependence - 1
Medical University of South Carolina
NCT00000248
Pharmacological Modulation of Cocaine Effects - 1
National Institute on Drug Abuse (NIDA)
NCT00000201
Risperidone Treatment in Dually-Diagnosed Individuals - 2
National Institute on Drug Abuse (NIDA)
NCT00000267
Evaluation of Benztropine for Cocaine Craving - 2
National Institute on Drug Abuse (NIDA)
NCT00000333
Disulfiram for Cocaine-Alcohol Abuse - 3
Yale University
NCT00000278
Effects of Labetalol on Human Cocaine Use - 8
National Institute on Drug Abuse (NIDA)
NCT00000291
Methylphenidate Raclopride Positron Emission Tomography (PET) Test - 11
National Institute on Drug Abuse (NIDA)
NCT00015301
Flupenthixol Treatment in Schizophrenic Cocaine Abusers - 1
National Institute on Drug Abuse (NIDA)
NCT00000266
IV Cocaine Abuse: A Laboratory Model - 1
New York State Psychiatric Institute
NCT00000212
Risperidone for the Treatment of Cocaine Dependence - 7
National Institute on Drug Abuse (NIDA)
NCT00000342
Prepulse Inhibition of Startle in Cocaine Dependence - 7
National Institute on Drug Abuse (NIDA)
NCT00015249
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 15 |
| Phase 3 | 1 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Cocaine-Related Disorders records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cocaine-Related Disorders trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cocaine-Related Disorders page
28 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- No Cocaine-Related Disorders trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
- National Institute on Drug Abuse (NIDA) sponsors the most Cocaine-Related Disorders trials on record, review their full trial history before evaluating a specific study. See National Institute on Drug Abuse (NIDA)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cocaine-Related Disorders condition card totals 28 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.