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NCT01036685 · ClinicalTrials.gov registry record

Cognitive Task Development and Implementation for Functional MRI Studies

A clinical trial, sponsored by National Institute on Drug Abuse (NIDA).

Completed
Registry status
525
Enrollment target

NCT01036685: Completed study, sponsored by National Institute on Drug Abuse (NIDA).

NCT01036685 is a clinical trial that has completed, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 525 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01036685 has completed, sponsored by National Institute on Drug Abuse (NIDA).

COMPLETED
Registry status
525 participants
Enrollment target

Study Summary

Background: * Drugs of abuse have effects on mood, behavior, thinking, and decision making that may encourage people to continue using them and make it difficult for them to stop. Researchers who study these effects are interested in developing new tests to evaluate how drugs and drug use affect different areas of the brain. * Magnetic resonance imaging (MRI) scans allow researchers to study brain activity and changes to brain function. When specific psychological tests are performed during functional MRI (fMRI) scans, researchers can examine the effects of drug use on the brain. By developing and testing new procedures for fMRI studies, more information can be obtained on brain function and activity in drug-using and non-drug-using individuals, and this information can help develop new treatments and therapies for substance abuse. Objectives: \- To develop, assess and refine of cognitive and affective tasks and determination of their practical feasibility and efficacy for both MRI and non-MRI application. Eligibility: * Healthy volunteers between 18 and 65 years of age who are willing to undergo MRI scanning. * Both drug-using and non-drug-using individuals will be selected for this study. Design: * Before the start of the study, participants may complete as assessment of medical and psychological history, and provide information about past or current drug use. Researchers will introduce the tasks to be performed and may have participants practice the tasks. * During the study, participants will be asked to do one or more tasks selected by the researchers. The tasks may be performed on a computer in an MRI machine, and may involve receiving rewards (such as money or sips of juice) for actions, memory and reaction-time tests, or other tests that involve responding to instructions on the screen. * Participants will receive compensation for their participation in the study, including hourly compensation for individual visits.

Primary Outcome

1\. To derive the parameters necessary to determine the reliability and validity of cognitive tasks.2. To determine the ability of various control and target populations to perform the tasks appropriately in and out of the MRI scanner.3. To determine the task parameters optimal for the activation of specific brain regions when employed during fMRI scanning.

Trial Details

FieldValue
Enrollment Target 525 participants
Start Date 2005-05-22

What the finished NCT01036685 record still lists

NCT01036685 is an observational study that tracks outcomes without assigning an intervention. The registered 525 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 0 interventions.

NCT01036685 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01036685 about?

NCT01036685 is a clinical study titled "Cognitive Task Development and Implementation for Functional MRI Studies". Background: * Drugs of abuse have effects on mood, behavior, thinking, and decision making that may encourage people to continue using them and make it difficult for them to stop. Researchers who study these effects are interested in developing new tests to evaluate how drugs and drug use affect di...

What is the current status of trial NCT01036685?

This trial is currently completed. The enrollment target is 525 participants. The study started on 2005-05-22.

Who is sponsoring clinical trial NCT01036685?

This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT01036685, the US trial registry maintained by the National Library of Medicine. NCT01036685 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.