Smith & Nephew

52 total trials 34 currently recruiting 9 completed

Trial Pipeline

RECRUITING

AETOS Shoulder System

NCT06319911

RECRUITING

Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry

NCT05915078

RECRUITING NA

Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears

NCT05444465

ACTIVE NOT RECRUITING

A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary Hip System

NCT06564636

ACTIVE NOT RECRUITING NA

To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System.

NCT04849884

ACTIVE NOT RECRUITING

A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis

NCT05197036

ACTIVE NOT RECRUITING

Safety and Effectiveness Study of OR3O™ Dual Mobility System in THA

NCT04325022

ACTIVE NOT RECRUITING

Safety and Performance Study of the Legion Porous System in Total Knee Arthroplasty

NCT03720782

ACTIVE NOT RECRUITING

Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial Inserts

NCT03687593

ACTIVE NOT RECRUITING

JOURNEY II XR Safety and Effectiveness PMCF

NCT03136887

ACTIVE NOT RECRUITING

JOURNEY™ II CR Total Knee System

NCT02440672

ACTIVE NOT RECRUITING

LEGION Hinge Safety and Efficacy Study

NCT02445443

COMPLETED

Safety and Performance of Journey II BCS Total Knee System Patient Reported Outcome Measures

NCT03903731

COMPLETED

R3 Delta Ceramic Acetabular System PAS U.S.

NCT03056534

COMPLETED NA

Evaluation Of An Advanced Borderless Dressing

NCT03146845

COMPLETED

Journey II Bi-Cruciate Stabilized (BCS) Total Knee System Retrospective Study

NCT03292003

COMPLETED NA

Achilles Tendon Repair With Bioinductive Implant

NCT02811003

COMPLETED NA

PICO Breast Reduction Clinical Study Looking at Incision Healing Complications

NCT01640366

COMPLETED NA

Trial of Versajet Compared With Conventional Treatment in Acute and Chronic Wounds

NCT01050673

COMPLETED

Ankle Joint Replacement Outcomes Study

NCT00503438

COMPLETED NA

A Safety and Efficacy Study of the Birmingham Hip Resurfacing System

NCT00611585

What the Pipeline for Smith & Nephew Shows

According to the ClinicalTrials.gov registry, Smith & Nephew is linked to 52 US clinical trials across every stage of research activity. Of those, 34 studies are currently recruiting — about 65% of the sponsor's indexed portfolio — and 9 are already marked complete, representing roughly 17% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Smith & Nephew reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 0 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Smith & Nephew is Total Knee Arthroplasty with 3 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial