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NCT00218049 · ClinicalTrials.gov registry record · Phase 1

Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals

A Phase 1 study, sponsored by National Institute on Drug Abuse (NIDA).

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT00218049: Clinical Trial Phase 1 study, sponsored by National Institute on Drug Abuse (NIDA).

NCT00218049 is a Phase 1 study that was terminated before completion, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00218049, a Phase 1 study, was terminated before completion, sponsored by National Institute on Drug Abuse (NIDA).

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

Cocaine dependence is a major public health problem; an effective primary treatment for cocaine dependent individuals has yet to be found. The purpose of this study is to determine the safety and effects of vanoxerine (GBR 12909) in treating cocaine dependent individuals.

Interventions

  • DRUG GBR 12909

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2004-12
Est. Completion 2005-07
Phase Phase 1

Why NCT00218049 stopped before completion

NCT00218049 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 1 intervention - of which GBR 12909 is the first listed.

NCT00218049 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00218049 about?

NCT00218049 is a clinical study titled "Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals". Cocaine dependence is a major public health problem; an effective primary treatment for cocaine dependent individuals has yet to be found. The purpose of this study is to determine the safety and effects of vanoxerine (GBR 12909) in treating cocaine dependent individuals.

What is the current status of trial NCT00218049?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2004-12. Estimated completion is 2005-07.

What interventions are being tested in trial NCT00218049?

The interventions under investigation include: GBR 12909 (DRUG).

Who is sponsoring clinical trial NCT00218049?

This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00218049's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00218049, the US trial registry maintained by the National Library of Medicine. NCT00218049 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.