National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

490 total trials 50 currently recruiting 398 completed

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors 490 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 398 completed. 69 of these trials are in Phase 3-4 (later-stage) and 178 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 25 trials.

Trial Pipeline

490 total, page 6 of 10

COMPLETED Phase 1

Long-Term Exercise Maintenance Via Internet Support

NCT00260117

COMPLETED NA

Metabolic Effects of Chemical Interactions in Toxicity

NCT00253773

COMPLETED Phase 3

Pioglitazone vs Vitamin E vs Placebo for Treatment of Non-Diabetic Patients With Nonalcoholic Steatohepatitis (PIVENS)

NCT00063622

COMPLETED Phase 2

Weight Management in Nonalcoholic Steatohepatitis

NCT00266019

COMPLETED NA

The Effect of Ethanol on Overnight Glucose Regulation in Type 2

NCT00566592

COMPLETED

Donor Recipient Kidney Function Following Open Surgical vs. Laparoscopic Kidney Donation

NCT00100516

COMPLETED Phase 2

Effects of Hydrocortisone, Melatonin, and Placebo on Jet Lag

NCT00097474

COMPLETED Phase 3

PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis C

NCT00100659

COMPLETED Phase 2

Podocyte Retinoids

NCT00098020

COMPLETED

Adrenal Function in Critical Illness

NCT00156767

COMPLETED NA

Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials

NCT00105352

COMPLETED Phase 3

Focal Segmental Glomerulosclerosis Clinical Trial (FSGS-CT)

NCT00135811

COMPLETED

TEDDY - The Environmental Determinants of Diabetes in the Young

NCT00279318

COMPLETED Phase 2

Uric Acid in Essential Hypertension in Children

NCT00288184

COMPLETED

Insulin Resistance in Severely Obese Patients

NCT00275223

COMPLETED Phase 3

Randomized Trial of EUS Neurolysis in Pancreas Cancer

NCT00279292

COMPLETED

Infectious Agents in Pediatric Crohn's

NCT00237055

COMPLETED NA

Program to Reduce Incontinence by Diet and Exercise

NCT00091988

COMPLETED

Genetics of Interstitial Cystitis

NCT00237081

COMPLETED NA

Reimbursement Effects on Enrollment in Obesity Treatment

NCT00250510

COMPLETED Phase 2

New Onset of Type 1 Diabetes Mycophenolate Mofetil-Daclizumab Clinical Trial

NCT00100178

COMPLETED NA

Screening for Barrett's Esophagus in Otolaryngology Patients

NCT00695227

COMPLETED Phase 3

Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)

NCT00081328

COMPLETED Phase 4

Exercise Training in Type 2 Diabetes and Hypertension

NCT00212303

COMPLETED Phase 2

Effects of Tumor Necrosis Factor (TNF)-Alpha Antagonism in Patients With Metabolic Syndrome

NCT00111956

COMPLETED NA

Gender, Obesity, C-Reactive Protein, and Oxidative Stress

NCT00079963

COMPLETED Phase 2

The Effect of Thyroid Hormone on Drug Elimination in Cancer Patients

NCT00080574

TERMINATED Phase 3

Minimally Invasive Surgical Therapy for BPH

NCT00064649

COMPLETED

Events Preceding Interstitial Cystitis (EPIC)

NCT00248664

COMPLETED NA

Metabolic Analysis in Human Sulfur Amino Acid Deficiency

NCT00253760

COMPLETED Phase 2

Combination Drug Therapy Followed by Single Drug Steroid Free Therapy to Prevent Organ Rejection in Kidney Transplantation

NCT00076570

COMPLETED

Obesity and Fatty Acid Flux Comparison Trials

NCT00074945

COMPLETED

Kidney Transplantation in Patients With Cystinosis

NCT00074516

COMPLETED

Improving Diabetes in Primary Care (IMPACT)

NCT00108927

COMPLETED

The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

NCT00072917

COMPLETED

Fat Cell Size in Insulin Resistance

NCT00341406

COMPLETED NA

Enhanced Internet Behavior Therapy for Treating Obesity

NCT00212238

COMPLETED NA

Videoendoscopic Drainage of Infected Pancreatic Collections

NCT00061269

COMPLETED NA

Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly

NCT00212147

COMPLETED Phase 1

Islet Transplantation for Patients With Type 1 Diabetes

NCT00073281

COMPLETED NA

Conservative Treatment of Postprostatectomy Incontinence

NCT00212264

COMPLETED NA

Peer-enhanced Intervention to Support Teen Weight Loss

NCT00285558

COMPLETED Phase 2

The Effect of Vitamin D and Calcium on Bone in Pediatric HIV

NCT00724178

COMPLETED Phase 2

Improving Outcomes in Patients With Kidney Disease Due to Diabetes

NCT00381134

COMPLETED NA

Evaluation of California's SB 19 Pupil Nutrition Act

NCT00067847

COMPLETED Phase 3

Steroid Treatment for Kidney Disease

NCT00065611

COMPLETED

ORWH:SCOR on Sex and Gender Factors Affecting Women's Incontinence

NCT00069368

COMPLETED Phase 2

Evaluating the Use of Thymoglobulin, Sirolimus, and Donor Bone Marrow With Kidney Transplantation Patients

NCT00062712

COMPLETED Phase 2

Treating Nonalcoholic Steatohepatitis With Pioglitazone

NCT00062764

COMPLETED Phase 2

Treating Nonalcoholic Steatohepatitis (NASH) With Metformin

NCT00063232

← Previous Page 6 of 10 Next →

Phase Distribution

PhaseTrial count
Phase 1 42
Phase 2 136
Phase 3 55
Phase 4 14

What the Pipeline for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Shows

According to the ClinicalTrials.gov registry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is linked to 490 US clinical trials across every stage of research activity. Of those, 50 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 398 are already marked complete, representing roughly 81% of the total.

The phase mix for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reports 69 late-stage studies (Phase 3 and Phase 4 combined) and 178 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is Obesity with 25 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.