National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

490 total trials 50 currently recruiting 398 completed

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors 490 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 398 completed. 69 of these trials are in Phase 3-4 (later-stage) and 178 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 25 trials.

Trial Pipeline

490 total, page 7 of 10

COMPLETED Phase 1

Safety and Pharmacokinetics (PK) of hOKT3g1 (Ala-Ala) in Type 1 Diabetes Mellitus (T1DM)

NCT00073255

COMPLETED NA

Vermont Diabetes Information System

NCT00109369

COMPLETED Phase 2

The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children

NCT00108901

COMPLETED Phase 2

Testosterone and Physical Function in HIV+ Men

NCT00260143

COMPLETED Phase 2

Substrate Cycling in Energy Metabolism

NCT00361751

COMPLETED NA

Epidemiology of Gallbladder Sludge and Stones in Pregnancy

NCT00131131

COMPLETED

Hepatitis C: Grading and Staging by MR

NCT00059397

COMPLETED Phase 2

Treatment of Cholestatic Pruritus With Sertraline

NCT00058903

COMPLETED Phase 2

Type 2 Diabetes Primary Prevention for At Risk Girls

NCT00063674

COMPLETED Phase 1

Wise Mind: Environmental Approach for Obesity Prevention

NCT00065039

COMPLETED Phase 1

Improving Body Image in Middle Schoolers

NCT00067652

COMPLETED NA

Increasing Physical Activity Levels in Low-Income Women

NCT00065026

TERMINATED NA

Treatment of Diabetic Nephropathy

NCT00065559

COMPLETED

The Role of Connective Tissue Growth Factor in the Development of Kidney Disease After Organ Transplantation

NCT00056784

COMPLETED Phase 4

The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers

NCT00339833

COMPLETED NA

Increased Gluconeogenesis is One Cause of Cystic Fibrosis Related Diabetes (CFRD)

NCT00082238

COMPLETED Phase 4

Low-Dose Peginterferon and Ribavirin to Treat Chronic Hepatitis C in Patients Infected With HCV Genotype 2 or 3

NCT00056862

COMPLETED Phase 1

Adjuvant Nutrition for Critically Ill Trauma Patients

NCT00067132

COMPLETED NA

Factors Affecting Caloric Regulation in Human Feeding

NCT00108784

COMPLETED Phase 2

Study of Thyrotropin-Releasing Hormone in Normal Volunteers and in Patients With Thyroid or Pituitary Abnormalities

NCT00054756

COMPLETED NA

Obesity Prevention in African American School Children

NCT00061165

COMPLETED Phase 3

Clopidogrel Prevention of Early Arteriovenous (AV) Fistula Thrombosis

NCT03289520

COMPLETED Phase 3

Aggrenox Prevention of Access Stenosis

NCT00067119

COMPLETED

Quality of Life in Pediatric Inflammatory Bowel Disease

NCT00061737

COMPLETED Phase 2

Sirolimus Therapy for Idiopathic and Lupus Membranous Nephropathy

NCT00050713

COMPLETED Phase 1

Prevention of Type 2 Diabetes Mellitus in Children

NCT00073268

COMPLETED Phase 4

Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes

NCT00212290

COMPLETED NA

Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men

NCT00470990

COMPLETED NA

Breaking Down Barriers to Diabetes Self-Care

NCT00142922

COMPLETED NA

Impact of Non-Commercialism Policy in Seattle Schools

NCT00063700

COMPLETED NA

A Cafeteria Based Study of Weight Gain Prevention

NCT00573482

COMPLETED NA

Modifying the Home Television Watching Environment

NCT00065052

COMPLETED Phase 3

Hepatitis C Antiviral Resistance in African-Americans

NCT00038974

COMPLETED NA

Evaluation of Diabetes Self-Management Consultant Care

NCT00109720

COMPLETED NA

Treatment of Binge Eating Disorder

NCT00041743

TERMINATED Phase 2

Trial of High-dose Urso in Primary Sclerosing Cholangitis

NCT00059202

TERMINATED NA

Pre-ESRD Syndrome in High Risk African Americans

NCT00224939

COMPLETED Phase 2

Sirolimus for Focal Segmental Glomerulosclerosis

NCT00040508

COMPLETED Phase 2

Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)

NCT00064753

COMPLETED Phase 1

Detection and Cytotoxic T Lymphocyte Therapy of Post-Transplant Lymphoproliferative Disorder After Liver Transplant

NCT00063648

COMPLETED Phase 3

Prevention of Osteoporosis in Men With Prostate Cancer

NCT00048841

COMPLETED

Esophageal Motility and Airway Defenses Among Infants

NCT00062452

COMPLETED Phase 2

Strength Training for Obesity Prevention

NCT00030160

COMPLETED NA

Treatment of Binge Eating Disorder

NCT00039936

COMPLETED Phase 4

Effectiveness of Brief Counseling for Weight Management

NCT00212199

COMPLETED NA

Family-Centered Diabetes Project - Sharing Wisdom

NCT00438126

COMPLETED Phase 2

Gamma Interferon Therapy for Chronic Hepatitis C

NCT00028275

COMPLETED Phase 4

Pegylated Interferon and Ribavirin to Treat Chronic Hepatitis C With and Without Kidney Disease

NCT00028093

COMPLETED

Glucocorticoid-induced Osteopenia in Children

NCT00289328

COMPLETED Phase 2

Leptin to Treat Severe Insulin Resistance - Pilot Study

NCT00027456

← Previous Page 7 of 10 Next →

Phase Distribution

PhaseTrial count
Phase 1 42
Phase 2 136
Phase 3 55
Phase 4 14

What the Pipeline for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Shows

According to the ClinicalTrials.gov registry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is linked to 490 US clinical trials across every stage of research activity. Of those, 50 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 398 are already marked complete, representing roughly 81% of the total.

The phase mix for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reports 69 late-stage studies (Phase 3 and Phase 4 combined) and 178 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is Obesity with 25 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.