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NCT00279292 · ClinicalTrials.gov registry record · Phase 3

Randomized Trial of EUS Neurolysis in Pancreas Cancer

A Phase 3 study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Completed
Registry status
Phase 3
Development phase
26
Enrollment target

NCT00279292: Completed Phase 3 study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

NCT00279292 is a Phase 3 study that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 26 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00279292, a Phase 3 study, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

COMPLETED
Registry status
Phase 3
Development phase
26 participants
Enrollment target

Study Summary

This is a clinical trial to determine more effective methods of controlling the pain in pancreatic cancer. Although narcotic pain medication are effective, they have many side effects and are underutilized due to social stigma and fear of addiction. Celiac plexus neurolysis is a nerve block procedure that has been shown to be effective in uncontrolled clinical trials. We hypothesized that celiac plexus neurolysis plus pain medication will be more effective and have fewer side effects than pain medication alone. We are evaluating the effectiveness of this standard pain medications with or without celiac plexus neurolysis in a randomized controlled trial. One half of the participants will receive pain medications only and the other half will receive pain medications plus neurolysis, delivered via an endoscopic ultrasound device placed in the stomach.

Interventions

  • PROCEDURE Celiac Plexus Neurolysis

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2004-08
Est. Completion 2007-01
Phase Phase 3

What the finished NCT00279292 record still lists

NCT00279292 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 1 intervention - of which Celiac Plexus Neurolysis is the first listed.

NCT00279292 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00279292 about?

NCT00279292 is a clinical study titled "Randomized Trial of EUS Neurolysis in Pancreas Cancer". This is a clinical trial to determine more effective methods of controlling the pain in pancreatic cancer. Although narcotic pain medication are effective, they have many side effects and are underutilized due to social stigma and fear of addiction. Celiac plexus neurolysis is a nerve block procedur...

What is the current status of trial NCT00279292?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 26 participants. The study started on 2004-08. Estimated completion is 2007-01.

What interventions are being tested in trial NCT00279292?

The interventions under investigation include: Celiac Plexus Neurolysis (PROCEDURE).

Who is sponsoring clinical trial NCT00279292?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00279292's enrollment target sits among peer trials

26 1937th of 2000 higher than 60 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00279292, the US trial registry maintained by the National Library of Medicine. NCT00279292 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.