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NCT00253760 · ClinicalTrials.gov registry record · NA

Metabolic Analysis in Human Sulfur Amino Acid Deficiency

A NA study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Completed
Registry status
NA
Development phase
15
Enrollment target

NCT00253760: Completed NA study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

NCT00253760 is a NA study that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00253760, a NA study, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

Varied food intake, disease, and genetic differences result in complex diet-health interactions. In principle, information-rich metabolic analyses combined with bioinformatic tools provide an approach to explore these interactions. This project is a feasibility study of the use of high-resolution 1H-nuclear magnetic resonance (NMR) to study metabolic perturbations induced by a deficiency in sulfur amino acids (SAA). The investigators will 1) test the hypothesis that deficient dietary intake of SAA in humans results in oxidation of reduced glutathione (GSH)/oxidized glutathione (GSSG) redox and 2) determine whether 1H-NMR of blood and urine detects metabolic changes due to SAA deficiency.

Interventions

  • DRUG dietary amino acids; cysteine and methionine

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2004-02
Est. Completion 2007-02
Phase NA

What the finished NCT00253760 record still lists

NCT00253760 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which dietary amino acids; cysteine and methionine is the first listed.

NCT00253760 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00253760 about?

NCT00253760 is a clinical study titled "Metabolic Analysis in Human Sulfur Amino Acid Deficiency". Varied food intake, disease, and genetic differences result in complex diet-health interactions. In principle, information-rich metabolic analyses combined with bioinformatic tools provide an approach to explore these interactions. This project is a feasibility study of the use of high-resolution 1H...

What is the current status of trial NCT00253760?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2004-02. Estimated completion is 2007-02.

What interventions are being tested in trial NCT00253760?

The interventions under investigation include: dietary amino acids; cysteine and methionine (DRUG).

Who is sponsoring clinical trial NCT00253760?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00253760's enrollment target sits among peer trials

15 1881st of 2000 higher than 92 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00253760, the US trial registry maintained by the National Library of Medicine. NCT00253760 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.