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NCT00253773 · ClinicalTrials.gov registry record · NA

Metabolic Effects of Chemical Interactions in Toxicity

A NA study of Oxidative Stress, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Completed
Registry status
NA
Development phase
15
Enrollment target
1
Study location

NCT00253773: Completed NA study of Oxidative Stress, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

NCT00253773 is a NA study of Oxidative Stress that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 15 participants, below the 86-participant average among 36 other Oxidative Stress trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00253773, a NA study of Oxidative Stress, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

This pilot study tests the feasibility of using GSH redox state and high resolution proton NMR spectroscopy (1H-NMR) to detect metabolic changes due to acetominophen and sulfur amino acid deficiency. Our central hypothesis is that the a 2-day sulfur amino acid deficiency will alter acetominophen metabolism, acetominophen will affect sulfur amino acid homeostasis, and the treatments together will alter the global metabolic profile, as measured by 1H-NMR spectroscopy.

Conditions Studied

Interventions

  • DRUG acetominophen, sulfer amino acids; cysteine and methionine

Study Locations (1)

Georgia

  • Emory University Hospital - Atlanta

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2005-01
Est. Completion 2007-11
Phase NA

What the finished NCT00253773 record still lists

NCT00253773 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 86-participant average among 36 other Oxidative Stress trials with a reported enrollment target (83% lower).

The record links to 1 condition, with Oxidative Stress appearing as the primary indexed condition, and to 1 intervention - of which acetominophen, sulfer amino acids; cysteine and methionine is the first listed.

NCT00253773 reports a single indexed study location in Georgia.

Frequently Asked Questions

What is clinical trial NCT00253773 about?

NCT00253773 is a clinical study titled "Metabolic Effects of Chemical Interactions in Toxicity". This pilot study tests the feasibility of using GSH redox state and high resolution proton NMR spectroscopy (1H-NMR) to detect metabolic changes due to acetominophen and sulfur amino acid deficiency. Our central hypothesis is that the a 2-day sulfur amino acid deficiency will alter acetominophen met...

What is the current status of trial NCT00253773?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2005-01. Estimated completion is 2007-11.

What conditions does trial NCT00253773 study?

This clinical trial studies the following conditions: Oxidative Stress.

What interventions are being tested in trial NCT00253773?

The interventions under investigation include: acetominophen, sulfer amino acids; cysteine and methionine (DRUG).

Who is sponsoring clinical trial NCT00253773?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00253773 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Oxidative Stress

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00253773's enrollment target sits among peer trials

15 32nd of 36 higher than 4 of 36 other Oxidative Stress trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Oxidative Stress trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00253773, the US trial registry maintained by the National Library of Medicine. NCT00253773 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.