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NCT00253773 · ClinicalTrials.gov registry record · NA

Metabolic Effects of Chemical Interactions in Toxicity

A NA study of Oxidative Stress, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Completed
Registry status
NA
Development phase
15
Enrollment target
1
Study location

NCT00253773 is a NA study of Oxidative Stress that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 15 participants, below the 86-participant average among 36 other Oxidative Stress trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00253773, a NA study of Oxidative Stress, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

This pilot study tests the feasibility of using GSH redox state and high resolution proton NMR spectroscopy (1H-NMR) to detect metabolic changes due to acetominophen and sulfur amino acid deficiency. Our central hypothesis is that the a 2-day sulfur amino acid deficiency will alter acetominophen metabolism, acetominophen will affect sulfur amino acid homeostasis, and the treatments together will alter the global metabolic profile, as measured by 1H-NMR spectroscopy.

Conditions Studied

Interventions

  • DRUG acetominophen, sulfer amino acids; cysteine and methionine

Study Locations (1)

Georgia

  • Emory University Hospital - Atlanta

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2005-01
Est. Completion 2007-11
Phase NA

What the Registry Record Tells You About NCT00253773

The ClinicalTrials.gov registry entry for NCT00253773 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 86-participant average among 36 other Oxidative Stress trials with a reported enrollment target (83% lower). The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Oxidative Stress appearing as the primary indexed condition, and to 1 intervention - of which acetominophen, sulfer amino acids; cysteine and methionine is the first listed.

NCT00253773 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.

Frequently Asked Questions

What is clinical trial NCT00253773 about?

NCT00253773 is a clinical study titled "Metabolic Effects of Chemical Interactions in Toxicity". This pilot study tests the feasibility of using GSH redox state and high resolution proton NMR spectroscopy (1H-NMR) to detect metabolic changes due to acetominophen and sulfur amino acid deficiency. Our central hypothesis is that the a 2-day sulfur amino acid deficiency will alter acetominophen met...

What is the current status of trial NCT00253773?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2005-01. Estimated completion is 2007-11.

What conditions does trial NCT00253773 study?

This clinical trial studies the following conditions: Oxidative Stress.

What interventions are being tested in trial NCT00253773?

The interventions under investigation include: acetominophen, sulfer amino acids; cysteine and methionine (DRUG).

Who is sponsoring clinical trial NCT00253773?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00253773 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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