National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

490 total trials 50 currently recruiting 398 completed

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors 490 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 398 completed. 69 of these trials are in Phase 3-4 (later-stage) and 178 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 25 trials.

Trial Pipeline

490 total, page 5 of 10

COMPLETED Phase 1

A Test of Iron Malabsorption in Patients With Iron Deficiency Anemia

NCT00399191

COMPLETED NA

Middle-School Based Primary Prevention Trial of Type 2 Diabetes

NCT00458029

COMPLETED

Assessment of Beta Cell Mass in Type 1 Diabetes With 11C-Dihydrotetrabenazine and PET Scan

NCT00351650

COMPLETED Phase 1

Efficacy of Increasing Physical Activity to Reduce Children's Visceral Fat

NCT00359957

COMPLETED

Gene Expression and Inflammation in Overweight Subjects

NCT00344266

COMPLETED NA

Nutritional Intervention to Prevent Diabetes

NCT00333554

COMPLETED Phase 2

Statewide (Rhode Island and Neighboring States) Partnerships for Worksite Weight Management

NCT00288145

COMPLETED

Study of Effects From Gastric Bypass Weight Loss on Brain Tissue

NCT00357344

COMPLETED Phase 3

Cinacalcet to Treat Familial Primary Hyperparathyroidism

NCT00325104

COMPLETED NA

Low Magnitude Mechanical Stimuli Effects on Bone Structure in ESRD

NCT00364234

COMPLETED NA

Effects of Caffeinated and Decaffeinated Coffee on Body Weight and Glucose Tolerance

NCT00305097

TERMINATED

Stem Cell Collection

NCT00316069

COMPLETED

Thyroid and Fat Tissue Metabolism

NCT00312715

COMPLETED Phase 2

Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver

NCT00323414

COMPLETED Phase 3

Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

NCT00371033

COMPLETED Phase 2

Treatment of Uterine Fibroids With the Selective Progesterone Receptor Modulator CDB-2914

NCT00290251

COMPLETED

Body Weight Regulation in Patients With Narcolepsy

NCT00283894

COMPLETED Phase 2

Frequent Hemodialysis Network: Daily Trial

NCT00264758

COMPLETED Phase 3

HALT Progression of Polycystic Kidney Disease Study B

NCT01885559

COMPLETED Phase 3

HALT Progression of Polycystic Kidney Disease Study A

NCT00283686

COMPLETED

Kidney Disease Biomarkers

NCT00255398

COMPLETED Phase 2

Effect of Lithium Carbonate on Low-Dose Radioiodine Therapy in Early Thyroid Cancer

NCT00251316

COMPLETED NA

A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy

NCT00294684

TERMINATED Phase 2

Chronic Sleep Deprivation as a Risk Factor for Metabolic Syndrome and Obesity

NCT00261898

COMPLETED

Assessment of Insulin Production From Native Pancreas in Patients With Pancreas Transplants

NCT00246844

COMPLETED Phase 3

Treatment of Nonalcoholic Fatty Liver Disease in Children (TONIC)

NCT00063635

COMPLETED Phase 2

Iron Depletion Therapy for Type 2 DM and NAFLD

NCT00230087

COMPLETED Phase 2

Effect of Omega-3 PUFA Supplementation in NAFLD Patients

NCT00230113

COMPLETED

Mechanisms of Diabetes Control After Weight Loss Surgery

NCT00571220

COMPLETED

T Cell Validation Study Using Blood Samples From Subjects With Recent Onset Type 1 Diabetes Mellitus

NCT00212329

COMPLETED

Cognitive Effects of Bariatric Surgery

NCT00671775

COMPLETED Phase 1

Dietary Variety Versus Dietary Fat Effects in Energy Intake

NCT00285571

COMPLETED NA

Myocardial Function & FFA Metabolism in HIV Metabolic Syndrome

NCT00656851

COMPLETED

Does Metabolic Syndrome Exist in Anorexia Nervosa?

NCT00271921

COMPLETED Phase 2

Pre-Transplant Treatment to Prevent Recurrence of Hepatitis C After Liver Transplantation

NCT00135798

COMPLETED NA

The Diabetes TeleCare Study

NCT00288132

COMPLETED Phase 2

Rituximab in New Onset Type 1 Diabetes

NCT00279305

TERMINATED Phase 2

SAMe to Treat Biliary Cirrhosis Symptoms

NCT00125281

COMPLETED Phase 4

Long-Term Lamivudine Therapy for Chronic Hepatitis B

NCT00120354

COMPLETED Phase 2

Obesity Assessment and Education Through the Internet

NCT00149682

COMPLETED NA

A Trial of Two Diets for Weight and Diabetes Management

NCT00729196

TERMINATED Phase 2

Imuran Dosing in Crohn's Disease Study

NCT00113503

COMPLETED NA

Use of Midlevel Providers in Diabetes Management

NCT00237094

COMPLETED Phase 2

Thyroid and Glucose and Energy Metabolism

NCT00106119

COMPLETED Phase 3

Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)

NCT00124306

COMPLETED NA

Development of Limited Contact CBT Treatment for IBS

NCT00248586

COMPLETED Phase 3

Trial to Compare Alfuzosin Versus Placebo in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

NCT00103402

COMPLETED Phase 1

Internet Weight Control for Bingeing Adolescents

NCT00125112

TERMINATED

Clinical and Laboratory Investigation of Humans With Informative Iron or Erythroid Phenotypes

NCT00102245

COMPLETED NA

Exercise and Pioglitazone for HIV-Metabolic Syndromes

NCT00639457

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Phase Distribution

PhaseTrial count
Phase 1 42
Phase 2 136
Phase 3 55
Phase 4 14

What the Pipeline for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Shows

According to the ClinicalTrials.gov registry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is linked to 490 US clinical trials across every stage of research activity. Of those, 50 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 398 are already marked complete, representing roughly 81% of the total.

The phase mix for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reports 69 late-stage studies (Phase 3 and Phase 4 combined) and 178 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is Obesity with 25 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.