National Heart, Lung, and Blood Institute (NHLBI)
National Heart, Lung, and Blood Institute (NHLBI) sponsors 501 registered US clinical trials on ClinicalTrials.gov, 62 of them currently recruiting, and 381 completed. 33 of these trials are in Phase 3-4 (later-stage) and 205 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atherosclerosis, with 12 trials.
Trial Pipeline
501 total, page 9 of 11
Effects of Miconazole on Blood Flow
NCT00004575
Vitamin Replacement in Abetalipoproteinemia
NCT00004574
Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon Angioplasty
NCT00004549
MRI Evaluation of Chest Pain
NCT00001961
Vascular Effects of Endothelium-Derived Versus Hemoglobin-Transported Nitric Oxide in Healthy Subjects
NCT00001963
Cyclosporine A to Treat Hypertrophic Cardiomyopathy (HCM)
NCT00001965
Studying the Effectiveness of Pacemaker Therapy in Children Who Have Thickened Heart Muscle
NCT00001960
A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow Failure
NCT00001962
Genetic Analysis of African-Americans With High Blood Pressure
NCT00353925
Modified Bone Marrow Stem Cell Transplantation for Chronic Myelogenous Leukemia
NCT00001144
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
NCT00000620
Study of TNFR:Fc (Enbrel) in the Treatment of Asthma
NCT00001893
Electromechanical Mapping to Evaluate Heart Muscle
NCT00001895
A Comparison of Two Treatments: Pacemaker and Percutaneous Transluminal Septal Ablation for Hypertrophic Cardiomyopathy
NCT00001894
Sample Collections From the Airways of Asthmatic Patients
NCT00001888
Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections
NCT00001890
Myocardial Contrast Echocardiography (MCE) to Check for Living and Working Heart Muscle
NCT00001891
Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow
NCT00003838
Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis
NCT00001885
Specimen Collection for Individuals With Lung Disease Associated With Rheumatoid Arthritis
NCT00001884
Stem Cell Transplantation for Metastatic Solid Tumors
NCT00001880
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease
NCT00001881
Collections of Blood and Stool Samples in Patients With Acute Hepatitis
NCT00001879
Quality Control of Cardiopulmonary Exercise Equipment
NCT00001883
Comparison of Echocardiographic Techniques in Diagnosis of Coronary Artery Disease
NCT00001889
Real Time 3-Dimensional Stress Echocardiography
NCT00001886
Factors Involved in Asthma and Airway Inflammation
NCT00001887
Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy
NCT00001874
The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers
NCT00001873
Cell Selection for Bone Marrow Transplants to Prevent Graft-Versus-Host-Disease
NCT00001872
Treatment of Pulmonary Sarcoidosis With Pentoxifylline
NCT00001877
Factors Contributing to Increased Left Ventricle Size in Patients With Abnormally Enlarged Hearts
NCT00001878
Study of Muscle Abnormalities in Patients With Specific Genetic Mutations
NCT00001871
Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia
NCT00029380
Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Melanoma
NCT00003552
Official Record of Patients Diagnosed With Lymphangioleiomyomatosis (LAM)
NCT00001869
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women
NCT00001752
Comparing Treatments for Multiple Myeloma
NCT00001750
Study of the Effects of Temperature on Metabolism in Human Muscle
NCT00001753
Medical Treatment for Diamond Blackfan Anemia
NCT00001749
HLA-Mismatched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematological Malignancies
NCT00001748
Racial Differences in Control of Blood Vessel Tone and Blood Flow
NCT00001747
Screening for Inherited Heart Disease
NCT00001746
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease
NCT00027196
Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa
NCT00027183
Peripheral Stem Cell Transplant in Treating Patients With Metastatic Kidney Cancer
NCT00003553
The Role of Cyclooxygenase Activity in the Endothelial Function of Hypertensive and Hypercholesterolemic Patients
NCT00001742
Study of Inherited Changes of Receptors Located on Blood Vessels
NCT00001741
Evaluation of Left Ventricular Volumes by Real-Time 3-Dimensional Echocardiography
NCT00001740
Magnetic Resonance Imaging of the Blood Vessels of the Heart
NCT00001638
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 87 |
| Phase 2 | 118 |
| Phase 3 | 29 |
| Phase 4 | 4 |
Therapeutic Areas
What the Pipeline for National Heart, Lung, and Blood Institute (NHLBI) Shows
According to the ClinicalTrials.gov registry, National Heart, Lung, and Blood Institute (NHLBI) is linked to 501 US clinical trials across every stage of research activity. Of those, 62 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 381 are already marked complete, representing roughly 76% of the total.
The phase mix for National Heart, Lung, and Blood Institute (NHLBI) reports 33 late-stage studies (Phase 3 and Phase 4 combined) and 205 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Heart, Lung, and Blood Institute (NHLBI) is Atherosclerosis with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.