National Heart, Lung, and Blood Institute (NHLBI)

501 total trials 62 currently recruiting 381 completed

National Heart, Lung, and Blood Institute (NHLBI) sponsors 501 registered US clinical trials on ClinicalTrials.gov, 62 of them currently recruiting, and 381 completed. 33 of these trials are in Phase 3-4 (later-stage) and 205 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atherosclerosis, with 12 trials.

Trial Pipeline

501 total, page 9 of 11

COMPLETED Phase 1

Effects of Miconazole on Blood Flow

NCT00004575

COMPLETED

Vitamin Replacement in Abetalipoproteinemia

NCT00004574

COMPLETED Phase 1

Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon Angioplasty

NCT00004549

COMPLETED Phase 2

MRI Evaluation of Chest Pain

NCT00001961

COMPLETED Phase 1

Vascular Effects of Endothelium-Derived Versus Hemoglobin-Transported Nitric Oxide in Healthy Subjects

NCT00001963

COMPLETED Phase 2

Cyclosporine A to Treat Hypertrophic Cardiomyopathy (HCM)

NCT00001965

COMPLETED Phase 2

Studying the Effectiveness of Pacemaker Therapy in Children Who Have Thickened Heart Muscle

NCT00001960

TERMINATED Phase 2

A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow Failure

NCT00001962

COMPLETED

Genetic Analysis of African-Americans With High Blood Pressure

NCT00353925

COMPLETED Phase 2

Modified Bone Marrow Stem Cell Transplantation for Chronic Myelogenous Leukemia

NCT00001144

COMPLETED Phase 3

Action to Control Cardiovascular Risk in Diabetes (ACCORD)

NCT00000620

COMPLETED Phase 2

Study of TNFR:Fc (Enbrel) in the Treatment of Asthma

NCT00001893

COMPLETED Phase 3

Electromechanical Mapping to Evaluate Heart Muscle

NCT00001895

COMPLETED Phase 2

A Comparison of Two Treatments: Pacemaker and Percutaneous Transluminal Septal Ablation for Hypertrophic Cardiomyopathy

NCT00001894

COMPLETED

Sample Collections From the Airways of Asthmatic Patients

NCT00001888

COMPLETED Phase 2

Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections

NCT00001890

COMPLETED Phase 3

Myocardial Contrast Echocardiography (MCE) to Check for Living and Working Heart Muscle

NCT00001891

COMPLETED Phase 2

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

NCT00003838

COMPLETED

Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis

NCT00001885

COMPLETED

Specimen Collection for Individuals With Lung Disease Associated With Rheumatoid Arthritis

NCT00001884

TERMINATED Phase 2

Stem Cell Transplantation for Metastatic Solid Tumors

NCT00001880

COMPLETED

Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease

NCT00001881

COMPLETED

Collections of Blood and Stool Samples in Patients With Acute Hepatitis

NCT00001879

COMPLETED

Quality Control of Cardiopulmonary Exercise Equipment

NCT00001883

COMPLETED Phase 2

Comparison of Echocardiographic Techniques in Diagnosis of Coronary Artery Disease

NCT00001889

COMPLETED Phase 2

Real Time 3-Dimensional Stress Echocardiography

NCT00001886

COMPLETED

Factors Involved in Asthma and Airway Inflammation

NCT00001887

COMPLETED

Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy

NCT00001874

COMPLETED Phase 2

The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers

NCT00001873

COMPLETED

Cell Selection for Bone Marrow Transplants to Prevent Graft-Versus-Host-Disease

NCT00001872

COMPLETED Phase 2

Treatment of Pulmonary Sarcoidosis With Pentoxifylline

NCT00001877

COMPLETED

Factors Contributing to Increased Left Ventricle Size in Patients With Abnormally Enlarged Hearts

NCT00001878

COMPLETED

Study of Muscle Abnormalities in Patients With Specific Genetic Mutations

NCT00001871

COMPLETED Phase 2

Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

NCT00029380

TERMINATED Phase 1

Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Melanoma

NCT00003552

COMPLETED

Official Record of Patients Diagnosed With Lymphangioleiomyomatosis (LAM)

NCT00001869

COMPLETED Phase 2

Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women

NCT00001752

COMPLETED Phase 2

Comparing Treatments for Multiple Myeloma

NCT00001750

COMPLETED Phase 1

Study of the Effects of Temperature on Metabolism in Human Muscle

NCT00001753

COMPLETED Phase 2

Medical Treatment for Diamond Blackfan Anemia

NCT00001749

COMPLETED Phase 1

HLA-Mismatched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematological Malignancies

NCT00001748

COMPLETED

Racial Differences in Control of Blood Vessel Tone and Blood Flow

NCT00001747

COMPLETED

Screening for Inherited Heart Disease

NCT00001746

COMPLETED

Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease

NCT00027196

COMPLETED

Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa

NCT00027183

COMPLETED Phase 2

Peripheral Stem Cell Transplant in Treating Patients With Metastatic Kidney Cancer

NCT00003553

COMPLETED

The Role of Cyclooxygenase Activity in the Endothelial Function of Hypertensive and Hypercholesterolemic Patients

NCT00001742

COMPLETED Phase 1

Study of Inherited Changes of Receptors Located on Blood Vessels

NCT00001741

COMPLETED

Evaluation of Left Ventricular Volumes by Real-Time 3-Dimensional Echocardiography

NCT00001740

COMPLETED

Magnetic Resonance Imaging of the Blood Vessels of the Heart

NCT00001638

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 118
Phase 3 29
Phase 4 4

What the Pipeline for National Heart, Lung, and Blood Institute (NHLBI) Shows

According to the ClinicalTrials.gov registry, National Heart, Lung, and Blood Institute (NHLBI) is linked to 501 US clinical trials across every stage of research activity. Of those, 62 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 381 are already marked complete, representing roughly 76% of the total.

The phase mix for National Heart, Lung, and Blood Institute (NHLBI) reports 33 late-stage studies (Phase 3 and Phase 4 combined) and 205 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Heart, Lung, and Blood Institute (NHLBI) is Atherosclerosis with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.