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NCT00353925 · ClinicalTrials.gov registry record
Genetic Analysis of African-Americans With High Blood Pressure
A clinical trial, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Completed
- Registry status
- 1,000
- Enrollment target
NCT00353925: Completed study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT00353925 is a clinical trial that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 1,000 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00353925 has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- COMPLETED
- Registry status
- 1,000 participants
- Enrollment target
Study Summary
The purpose of this study is to learn if kinase, a protein found in the heart, contributes to thickening of the heart muscle in people with high blood pressure. A protein called myosin causes the heart to contract and relax. It is thought that kinase changes myosin to make it work better at different heart rates. This study will try to determine if, in some people with high blood pressure, the different forms of this protein cause changes in the heart. If the protein affects the size of the heart, it might be possible to use it to improve heart function after an injury, such as a heart attack. African-Americans with high blood pressure will be eligible for this study. Current data show that of almost 900 multi-ethnic individuals, the particular form of kinase under study in this project is found exclusively in the African-American population. Study participants will have two tubes of blood drawn for DNA testing to determine what form of kinase is present. An electrocardiogram will also be done if a recent one is not available. Some people may also have an echocardiogram, an ultrasound test to image the heart.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 1999-10-05 |
| Est. Completion | 2007-12-10 |
What the finished NCT00353925 record still lists
NCT00353925 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT00353925 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00353925 about?
NCT00353925 is a clinical study titled "Genetic Analysis of African-Americans With High Blood Pressure". The purpose of this study is to learn if kinase, a protein found in the heart, contributes to thickening of the heart muscle in people with high blood pressure. A protein called myosin causes the heart to contract and relax. It is thought that kinase changes myosin to make it work better at differe...
What is the current status of trial NCT00353925?
This trial is currently completed. The enrollment target is 1,000 participants. The study started on 1999-10-05. Estimated completion is 2007-12-10.
Who is sponsoring clinical trial NCT00353925?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
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