National Heart, Lung, and Blood Institute (NHLBI)

501 total trials 62 currently recruiting 381 completed

National Heart, Lung, and Blood Institute (NHLBI) sponsors 501 registered US clinical trials on ClinicalTrials.gov, 62 of them currently recruiting, and 381 completed. 33 of these trials are in Phase 3-4 (later-stage) and 205 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atherosclerosis, with 12 trials.

Trial Pipeline

501 total, page 10 of 11

COMPLETED Phase 2

Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults

NCT00001637

COMPLETED Phase 2

Safety and Effectiveness of Coronary Magnetic Resonance Angiography (CMRA) Imaging

NCT00001633

COMPLETED

Investigation Into the Use of Ultrasound Technique in the Evaluation of Heart Disease

NCT00001632

COMPLETED Phase 2

Study of Blood Flow in Heart Muscle

NCT00001631

COMPLETED Phase 1

Treatment of Autoimmune Thrombocytopenia (AITP)

NCT00001630

COMPLETED

Collection of Blood and Bone Marrow From Healthy Volunteers and Patients for Research Purposes

NCT00001627

COMPLETED Phase 3

The Role of Angiotensin Type I Receptor in the Regulation of Human Peripheral Vascular Function

NCT00001628

COMPLETED Phase 3

The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function

NCT00001629

COMPLETED Phase 2

Comparing Therapies for the Treatment of Severe Aplastic Anemia

NCT00001626

COMPLETED NA

Bone Marrow Transplant Studies for Safe and Effective Treatment of Leukemia

NCT00001623

COMPLETED Phase 1

Study of the Response of Human Small Blood Vessels

NCT00001622

COMPLETED Phase 1

Effect of Insulin on Endothelin-Dependent Vascular Tone in the Forearm Circulation

NCT00001624

COMPLETED

Evaluation and Treatment of Patients With Lung Disease Not Participating in Research

NCT00001621

COMPLETED

Segmental Bronchoalveolar Lavage

NCT00001618

COMPLETED

Magnetic Resonance Imaging at Different Levels of Magnetic Intensity

NCT00001619

COMPLETED Phase 1

Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With Cyclosporine

NCT00001533

COMPLETED

Long Term Effects of Enalapril and Losartan on Genetic Heart Disease

NCT00001534

COMPLETED

Potential Role of CMV in Restenosis Following Angioplasty, in Atherosclerosis, and in Endothelial Dysfunction

NCT00001531

COMPLETED

Long-Term Results of DDD Pacing in Obstructive Hypertrophic Cardiomyopathy

NCT00001530

COMPLETED

Analysis of Heart Muscle Function Following Exercise in Patients With Heart Disease

NCT00001528

COMPLETED

The Women's Health Initiative Memory Study (The WHIMS Study)

NCT00685009

COMPLETED

Role of Endothelin in the Regulation of Vascular Tone in Patients With Essential Hypertension

NCT00001527

COMPLETED

Effect of High Levels of Oxygen and Smoking on the Lungs in Human Volunteers

NCT00001464

COMPLETED

Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals

NCT00001462

COMPLETED

Study of the Interaction Between the Cells Lining Blood Vessels and Angiotensin-Converting Enzyme

NCT00001461

COMPLETED

Evaluation of Patients With Heart Disease Not Eligible for Research Protocols

NCT00001458

COMPLETED NA

Evaluation and Treatment of Heart Disease in Patients Not Participating in Research

NCT00001460

COMPLETED

Analysis of Heart Muscle Function in Patients With Heart Disease and Normal Volunteers

NCT00001459

COMPLETED Phase 3

Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)

NCT00000579

COMPLETED Phase 2

PET Scan to Determine Areas of Blood Flow and Activity in the Hearts of Patients With Heart Disease Taking Beta-Blockers

NCT00001402

COMPLETED Phase 1

Gene Therapy for the Treatment of Fanconi's Anemia Type C

NCT00001399

COMPLETED

Outpatient Evaluation of Patients With Known or Suspected Heart Disease

NCT00001400

COMPLETED

Evaluation, Treatment, and Training for Patients With Blood Disorders

NCT00001397

COMPLETED Phase 1

Natural History and Results of Dual Chamber (DDD) Pacemaker Therapy of Children With Obstructive Hypertrophic Cardiomyop...

NCT00001396

COMPLETED Phase 1

Stem Cell Factor Medication for Aplastic Anemia

NCT00001398

COMPLETED

Evaluation of Patients With Known or Suspected Heart Disease

NCT00001313

COMPLETED

Investigation of Heart Function in Patients With Heart Valve Defects

NCT00001314

COMPLETED Phase 3

Trial of Nonpharmacologic Interventions in Elderly (TONE)

NCT00000535

COMPLETED

Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers

NCT00001204

COMPLETED

Diagnosis and Treatment of Pheochromocytoma

NCT00001229

COMPLETED

Lipoprotein Metabolism in Normal Volunteers and Patients With Abnormal Levels of Lipoproteins

NCT00001226

COMPLETED

Family Studies of Inherited Heart Disease

NCT00001225

COMPLETED

Collection of Blood From Patients With Pancytopenia

NCT00001214

COMPLETED

Deferoxamine for the Treatment of Hemochromatosis

NCT00001203

COMPLETED

Evaluating Electrocardiogram (ECG) Abnormalities From Young Adulthood Through Middle Age

NCT00556751

COMPLETED

Evaluation of the Causes and Disease Processes of Chronic Lung Disease

NCT00001183

COMPLETED Phase 2

Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia

NCT00001197

COMPLETED

Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure

NCT00001176

COMPLETED

Evaluation of Lipoproteins

NCT00001168

COMPLETED

Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of Lipoproteins

NCT00001154

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 118
Phase 3 29
Phase 4 4

What the Pipeline for National Heart, Lung, and Blood Institute (NHLBI) Shows

According to the ClinicalTrials.gov registry, National Heart, Lung, and Blood Institute (NHLBI) is linked to 501 US clinical trials across every stage of research activity. Of those, 62 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 381 are already marked complete, representing roughly 76% of the total.

The phase mix for National Heart, Lung, and Blood Institute (NHLBI) reports 33 late-stage studies (Phase 3 and Phase 4 combined) and 205 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Heart, Lung, and Blood Institute (NHLBI) is Atherosclerosis with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.