National Heart, Lung, and Blood Institute (NHLBI)
National Heart, Lung, and Blood Institute (NHLBI) sponsors 501 registered US clinical trials on ClinicalTrials.gov, 62 of them currently recruiting, and 381 completed. 33 of these trials are in Phase 3-4 (later-stage) and 205 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atherosclerosis, with 12 trials.
Trial Pipeline
501 total, page 10 of 11
Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults
NCT00001637
Safety and Effectiveness of Coronary Magnetic Resonance Angiography (CMRA) Imaging
NCT00001633
Investigation Into the Use of Ultrasound Technique in the Evaluation of Heart Disease
NCT00001632
Study of Blood Flow in Heart Muscle
NCT00001631
Treatment of Autoimmune Thrombocytopenia (AITP)
NCT00001630
Collection of Blood and Bone Marrow From Healthy Volunteers and Patients for Research Purposes
NCT00001627
The Role of Angiotensin Type I Receptor in the Regulation of Human Peripheral Vascular Function
NCT00001628
The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function
NCT00001629
Comparing Therapies for the Treatment of Severe Aplastic Anemia
NCT00001626
Bone Marrow Transplant Studies for Safe and Effective Treatment of Leukemia
NCT00001623
Study of the Response of Human Small Blood Vessels
NCT00001622
Effect of Insulin on Endothelin-Dependent Vascular Tone in the Forearm Circulation
NCT00001624
Evaluation and Treatment of Patients With Lung Disease Not Participating in Research
NCT00001621
Segmental Bronchoalveolar Lavage
NCT00001618
Magnetic Resonance Imaging at Different Levels of Magnetic Intensity
NCT00001619
Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With Cyclosporine
NCT00001533
Long Term Effects of Enalapril and Losartan on Genetic Heart Disease
NCT00001534
Potential Role of CMV in Restenosis Following Angioplasty, in Atherosclerosis, and in Endothelial Dysfunction
NCT00001531
Long-Term Results of DDD Pacing in Obstructive Hypertrophic Cardiomyopathy
NCT00001530
Analysis of Heart Muscle Function Following Exercise in Patients With Heart Disease
NCT00001528
The Women's Health Initiative Memory Study (The WHIMS Study)
NCT00685009
Role of Endothelin in the Regulation of Vascular Tone in Patients With Essential Hypertension
NCT00001527
Effect of High Levels of Oxygen and Smoking on the Lungs in Human Volunteers
NCT00001464
Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals
NCT00001462
Study of the Interaction Between the Cells Lining Blood Vessels and Angiotensin-Converting Enzyme
NCT00001461
Evaluation of Patients With Heart Disease Not Eligible for Research Protocols
NCT00001458
Evaluation and Treatment of Heart Disease in Patients Not Participating in Research
NCT00001460
Analysis of Heart Muscle Function in Patients With Heart Disease and Normal Volunteers
NCT00001459
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)
NCT00000579
PET Scan to Determine Areas of Blood Flow and Activity in the Hearts of Patients With Heart Disease Taking Beta-Blockers
NCT00001402
Gene Therapy for the Treatment of Fanconi's Anemia Type C
NCT00001399
Outpatient Evaluation of Patients With Known or Suspected Heart Disease
NCT00001400
Evaluation, Treatment, and Training for Patients With Blood Disorders
NCT00001397
Natural History and Results of Dual Chamber (DDD) Pacemaker Therapy of Children With Obstructive Hypertrophic Cardiomyop...
NCT00001396
Stem Cell Factor Medication for Aplastic Anemia
NCT00001398
Evaluation of Patients With Known or Suspected Heart Disease
NCT00001313
Investigation of Heart Function in Patients With Heart Valve Defects
NCT00001314
Trial of Nonpharmacologic Interventions in Elderly (TONE)
NCT00000535
Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers
NCT00001204
Diagnosis and Treatment of Pheochromocytoma
NCT00001229
Lipoprotein Metabolism in Normal Volunteers and Patients With Abnormal Levels of Lipoproteins
NCT00001226
Family Studies of Inherited Heart Disease
NCT00001225
Collection of Blood From Patients With Pancytopenia
NCT00001214
Deferoxamine for the Treatment of Hemochromatosis
NCT00001203
Evaluating Electrocardiogram (ECG) Abnormalities From Young Adulthood Through Middle Age
NCT00556751
Evaluation of the Causes and Disease Processes of Chronic Lung Disease
NCT00001183
Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia
NCT00001197
Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure
NCT00001176
Evaluation of Lipoproteins
NCT00001168
Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of Lipoproteins
NCT00001154
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 87 |
| Phase 2 | 118 |
| Phase 3 | 29 |
| Phase 4 | 4 |
Therapeutic Areas
What the Pipeline for National Heart, Lung, and Blood Institute (NHLBI) Shows
According to the ClinicalTrials.gov registry, National Heart, Lung, and Blood Institute (NHLBI) is linked to 501 US clinical trials across every stage of research activity. Of those, 62 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 381 are already marked complete, representing roughly 76% of the total.
The phase mix for National Heart, Lung, and Blood Institute (NHLBI) reports 33 late-stage studies (Phase 3 and Phase 4 combined) and 205 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Heart, Lung, and Blood Institute (NHLBI) is Atherosclerosis with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.