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ClinicalTrials.gov 1 recruiting now official registry

Coronary Disease clinical trials

1 of 36 indexed Coronary Disease trials are currently recruiting.

36 US clinical trials · 1 currently recruiting

Coronary Disease is the subject of 36 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 10 of these trials.

The research picture

Coronary Disease has 36 registered US clinical trials, 1 of them open to new participants right now, about 3% of the total.

1
recruiting participants now
3%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
10
top sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Phase 26Phase 35

Active & Recent Trials

36 total, page 1 of 1

RECRUITING NA 5,000 participants

Evaluating New Radiation Techniques for Cardiovascular Imaging

National Heart, Lung, and Blood Institute (NHLBI)

NCT01621594

ACTIVE NOT RECRUITING 11,737 participants

Bogalusa Heart Study

Tulane University

NCT00005129

ACTIVE NOT RECRUITING 6,340 participants

University of North Carolina Alumni Heart Study

Duke University

NCT00005398

ACTIVE NOT RECRUITING 5,888 participants

Cardiovascular Health Study (CHS)

National Heart, Lung, and Blood Institute (NHLBI)

NCT00005133

ACTIVE NOT RECRUITING 5,306 participants

The Jackson Heart Study of Cardiovascular Disease Among African Americans

National Heart, Lung, and Blood Institute (NHLBI)

NCT00005485

ACTIVE NOT RECRUITING 2,314 participants

Mediators of Atherosclerosis in South Asians Living in America

University of California, San Francisco

NCT01207167

ACTIVE NOT RECRUITING 105 participants

Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy

Johns Hopkins University

NCT02694094

COMPLETED Phase 3 10,251 participants

Action to Control Cardiovascular Risk in Diabetes (ACCORD)

National Heart, Lung, and Blood Institute (NHLBI)

NCT00000620

COMPLETED NA 5,179 participants

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

NYU Langone Health

NCT01471522

COMPLETED 5,034 participants

XIENCE V® Everolimus Eluting Coronary Stent System USA Post-Approval Study (XIENCE V® USA Long Term Follow-up Cohort)

Abbott Medical Devices

NCT01120379

COMPLETED Phase 3 2,136 participants

Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease

Duke University

NCT00023595

COMPLETED NA 1,500 participants

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

Stanford University

NCT02100722

COMPLETED 1,395 participants

Examining How Heart Disease Risk Factors Affect Healthy Aging (The Chicago Healthy Aging Study [CHAS])

Northwestern University

NCT00626379

COMPLETED Phase 3 1,100 participants

A Coronary IVUS Study to Compare Torcetrapib/Atorvastatin to Atorvastatin Alone in Subjects With Coronary Heart Disease

Pfizer

NCT00134173

COMPLETED Phase 3 911 participants

IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium.

Tufts Medical Center

NCT00091507

COMPLETED 715 participants

Heart Rate Variability and Sudden Cardiac Death

Columbia University

NCT00005235

COMPLETED 650 participants

Comparison of Two Methods to Diagnose Coronary Artery Disease

Johns Hopkins University

NCT00063531

COMPLETED Phase 2 389 participants

Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery

Duke University

NCT00041392

COMPLETED Phase 2 360 participants

MRI Evaluation of Chest Pain

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001961

COMPLETED 324 participants

Plaque Inflammation and Dysfunctional HDL in AIM-HIGH

University of Washington

NCT00880178

COMPLETED Phase 2 309 participants

Estrogen, HDL, and Coronary Heart Disease in Women

Tufts University

NCT00083824

COMPLETED NA 287 participants

Collaborative Cardiac Care Project

US Department of Veterans Affairs

NCT00105664

COMPLETED NA 250 participants

Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation

Baylor Research Institute

NCT00224809

COMPLETED 213 participants

Detection of Coronary Artery Calcification: Comparison of Volumetric and Electron Beam Computed Tomography

National Institutes of Health Clinical Center (CC)

NCT00001836

COMPLETED 209 participants

Study of the Interaction Between the Cells Lining Blood Vessels and Angiotensin-Converting Enzyme

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001461

COMPLETED Phase 3 200 participants

Myocardial Contrast Echocardiography (MCE) to Check for Living and Working Heart Muscle

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001891

COMPLETED NA 170 participants

Sapphire 3 CTO Study

OrbusNeich

NCT06358508

COMPLETED 125 participants

Atherosclerosis in the Coronary and Carotid Arteries

National Heart, Lung, and Blood Institute (NHLBI)

NCT00080587

COMPLETED Phase 2 110 participants

Custodiol-HTK (Histidine-tryptophan-ketoglutarate) Solution as a Cardioplegic Agent

Marc Sakwa, MD

NCT01681095

COMPLETED 45 participants

Cardiac Computed Tomography In the Management of Patients With indeterminAte or inConclusive Stress Tests

Corewell Health East

NCT00541203

COMPLETED NA 31 participants

Time Restricted Feeding for Weight Loss and Cardio-protection

University of Illinois at Chicago

NCT02948517

COMPLETED Phase 2 25 participants

Effects of Angiotensin-Converting Enzyme Inhibitor (Ramipril) Therapy on Blood Vessel Inflammation

National Heart, Lung, and Blood Institute (NHLBI)

NCT00005928

COMPLETED Phase 2 25 participants

Nitric Oxide Inhalation Therapy to Relieve Chest Pain in Patients With Coronary Artery Disease

National Heart, Lung, and Blood Institute (NHLBI)

NCT00014040

COMPLETED NA 12 participants

Pharmacokinetics of Everolimus in Absorb BVS in Patients With Coronary Artery Lesions

Abbott Medical Devices

NCT02229864

COMPLETED 10 participants

Platelet Activation Markers in Pediatric Cardiac Surgery

Weill Medical College of Cornell University

NCT00450151

COMPLETED NA

Effects of Training Intensity on the CHD Risk Factors in Postmenopausal Women

National Center for Research Resources (NCRR)

NCT00000108

Phase Distribution

PhaseTrial count
Phase 2 6
Phase 3 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Coronary Disease Trial Landscape

36 indexed Coronary Disease studies · 1 recruiting (3%).

Phase mix: 5 late (III/IV) vs 6 early (I/II).

Top sponsor: National Heart, Lung, and Blood Institute (NHLBI) (10 trials), 9 others listed. 36 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Coronary Disease?

PlainTrial tracks 36 US clinical trials for Coronary Disease, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Coronary Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.